Psychological consequences of the COVID-19 pandemic are increasingly being reported in the scientific literature. The purpose — to assess the level of anxiety and depression in patients with cardiological complaints with concomitant cardiovascular pathology during the acute period of COVID-19 and after discharge from the Infectious Diseases Hospital. Material and methods.An observational cross-sectional study of 129 patients with concomitant cardiological pathology was conducted. All patients completed the Spielberg — Hanin questionnaire and the Beck scale. Results.Personal and situational anxiety was statistically significantly more often registered among patients in hospital with COVID-19 than in those hospitalized in the Cardiology Department (p=0.002; p=0.001). The chances of depression in patients hospitalized in the Cardiology department were 2.82 times lower compared to patients with COVID-19, p=0.045. Among hospitalized patients with COVID-19 and discharged from the Infectious Diseases Hospital, increased situational anxiety was registered in almost all patients from the two groups (92.5; 95.92%), which may be due to the presence of COVID-19. Conclusions.Anxiety (personal and situational) and depression were statistically significantly more often registered among hospitalized patients with COVID-19 with cardiovascular complaints, compared with patients hospitalized in a Cardiology Hospital without COVID-19. In patients with cardiological pathology who had had COVID-19, increased anxiety and depression persist for six months after discharge.