Challenges In Care Of Patients Research Articles

Implementation of evidence-based practice and its correlates among nurses working in southern Ethiopia

BackgroundEvidence-based utilization is crucial for improving overall patient care quality, nursing practice, and building trust in decision-making with patient preferences to solve clinical challenges in patient care, but its practice is relatively low. ObjectiveTo assess the implementation of evidence-based practice (IEBP) and its correlates among nurses working in west Arsi zone public hospitals, Ethiopia. MethodAn institutional-based cross-sectional study design was employed using structured, interviewer-administered, pretested data from June 1 to July 30, 2022 and entered into epidata version 4.4.1 statistical software and exported to SPSS version 25 for further analysis. ResultsA total of 385 nurses responded the questionnaire, with 100 % response rate. Majority of participants 194 (50.4 %) were females with mean age of 32.02 (SD ± 6.8) years. The overall mean implementation of EBP among nurses was found to be 11.4 ± 8.53. Attitude, self-efficacy, working in referral hospital, being diploma in the level of education (β: −3.925; 95 % CI:(-6.399- (-1.451), knowledge of nurses toward EBP (β: 1.213; 95 % CI: 0.989–1.438) and availability of job rotation (β: 3.475; 95 % CI: 1.20–3.750) were significantly associated with the mean score of EBP utilization at a p-value ≤ 0.001. ConclusionA significant proportion of nurses use evidence-based practice infrequently. Knowledge, Attitude, self-efficacy, hospital level, level of education, and availability of job rotation, were the variables that contributed to the low utilization of evidence-based practice. It is recommended that integrating EBP training into nursing education curricula, establishing EBP training workshops, and research mentorship programs at the workplace are needed.

Implementing integrated care in ophthalmology: a community case study.

In 2017, in a context of financial and patient care challenges, Moorfields Eye Hospital in the borough of Croydon launched the first Ophthalmology Integrated Care Contract in the United Kingdom. A realistic, systematic approach is presented for an efficient implementation of an integrated care ophthalmology contract under a lead provider. The main elements of the new contract are portrayed. A new healthcare contract that would lead to system-wide transformation requires significant time commitment, vision, shared narrative, leadership, multi-functional working culture, shared accountability of all participating parties and education and support of all parties involved. Key levers to elevate the quality of care are collaborative relationships between health professionals, investing in information and technology and facilitating bottom-up innovation. System-wide changes such, as integrated care contracts are possible, although the interplay between context, design and implementation is more complex than expected.

Anti-inflammatory and Antioxidative Potential of Herbs and Fruits in the Management of Inflammatory Bowel Disease Beyond Medications

Inflammatory Bowel Disease (IBD), a chronic inflammatory condition of the gastrointestinal tract, primarily encompasses ulcerative colitis and Crohn's disease. Characterized by recurring inflammation, IBD is marked by its unpredictability and complexity. Crohn's disease may impact any part of the digestive system, causing significant ulcerations, whereas ulcerative colitis is mainly restricted to the colon, leading to persistent damage and ulcers. The intermittent nature of IBD, alternating between remission and active flare-ups, presents continuous challenges in patient care and treatment. Its etiology is multifaceted, involving a combination of genetic susceptibility, environmental triggers, and immune system malfunctions. Symptomatically diverse, IBD can manifest as abdominal discomfort, diarrhea, weight loss, and fatigue, complicating the establishment of uniform treatment protocols. Traditional pharmacological treatments often offer limited relief and may introduce side effects, necessitating frequent adjustments in therapy. This disease profoundly impacts not only the physical well-being of individuals but also their overall quality of life, calling for a comprehensive and individualized management approach. This review delves into the potential of herbs and fruits in IBD management, examining their proximate composition and the roles their anti-inflammatory and antioxidant properties play in enhancing gut health.

Socio-economic and environmental factors associated with community-acquired pressure injuries: A mixed method study

AimsTo: (1) report on the prevalence of community-acquired pressure injuries (CAPIs) in patients admitted into the acute care setting; (2) examine the socio-economic and home environment associated with CAPIs; and (3) understand the challenges of caring for patients with CAPIs at home. MethodsThis mixed-method study recruited patients admitted with CAPIs in the acute care hospital between March 2021 to June 2022. The hospital's pressure injury (PI) database was used to screen patients admitted with CAPIs. A purposive sample of CAPI patients and their caregivers participated in this study. A cross-sectional survey study was first performed to examine the prevalence of CAPIs and the socio-economic and home environment factors. Semi-structured interviews were conducted to understand the caregivers' challenges in caring for patients with CAPIs at home. ResultsThe CAPI prevalence was reported at 1.1 % during the study period (1039 had CAPIs out of 97 912 patients admitted to the hospital). A total of 70 caregivers and patients consented to participate in the study. The mean age of patients was 84.2 (SD = 10.4) years old; 68.6 % (n = 48) were females. Majority presented with a deep tissue injury (DTI) (37.1 %; n = 26) or unstageable PI (31.4 %; n = 22). More than half of the patients had alternating air mattresses at home (54.3 %; n = 38), and only 10 % (n = 7) had positioning wedges and used a sliding sheet for turning. The mean age of the caregivers was 43.4 years old (SD = 13.1), and 84.3 % (n = 59) were female. Continuous data were summarised using means and standard deviations, and categorical data were summarised using frequencies and percentages. Logistic regression found no significant socio-demographic and clinical predictors of patients having PI stages 2, 3, and 4 compared to patients with DTI and unstageable PI. Challenges to caring for PI at home included high financial burden, physical limitations, and personal challenges in CAPIs management. ConclusionCAPIs are prevalent among older patients admitted to the acute care setting. Understanding the influence of socio-economic factors is crucial for developing comprehensive strategies to mitigate the occurrence and impact of PIs. Ongoing support and education to the caregivers in the community is essential to address the reported challenges in PI care.

Primary care needs to rise to the challenge of caring for patients during climate disasters

Primary care needs to rise to the challenge of caring for patients during climate disasters

Determinants of Bone-Modifying Agent Prescribing for Metastatic Castration-Resistant Prostate Cancer in a National Health Care Delivery System.

Despite guidelines recommending bone-modifying agents (BMAs) to decrease skeletal-related events (SREs) in men with metastatic castration-resistant prostate cancer (mCRPC), BMAs are underutilized. In this retrospective cohort study, we report the factors associated with BMA use in a national health care delivery system. We used the Veterans Affairs Corporate Data Warehouse to identify men with mCRPC between 2010 and 2017. BMA prescribing frequency was evaluated, and the association between patient- and disease-specific factors with BMA use was assessed using multivariable logistic regression. Among 3,980 men identified with mCRPC (mean age 73.5 years, 29% Black), 47% received a BMA; median time to BMA from start of mCRPC treatment was 102 days. Factors associated with BMA use included previous BMA use (adjusted odds ratio [aOR], 7.81 [95% CI, 6.48 to 9.47]), diagnosis code for bone metastases (aOR, 1.26 [95% CI, 1.08 to 1.46]), and concomitant corticosteroid use (aOR, 1.53 [95% CI, 1.29 to 1.82]). Decreased BMA use was associated with advancing age (aOR, 0.85 per 10 years [95% CI, 0.78 to 0.92]), Charlson comorbidity index ≥2 (aOR, 0.76 [95% CI, 0.63 to 0.93]), Black race (aOR, 0.83 [95% CI, 0.70 to 0.98]), and decreased estimated glomerular filtration rate (eGFR; aOR, 0.19 [95% CI, 0.11 to 0.32] for eGFR 0-29 mL/minutes; aOR, 0.76 [95% CI, 0.64 to 0.91] for 30-59 mL/minutes). Patients who are older, Black, or have more comorbidities are less likely to receive guideline concordant care to prevent SREs. These observations highlight the unique challenges of caring for patients with mCRPC and the need for future studies to increase BMA use in these populations.

Making in the Midst of a Pandemic

The COVID-19 pandemic posed unprecedented challenges in patient care, prompting frontline clinicians globally to devise novel solutions. This article highlights the creativity of clinicians who adapted to meet the evolving standards of care. The researchers explored the scale of clinician awareness of the novel devices and protocols that were being made. A thematic analysis revealed rapid team coordination, supportive management, acknowledgment of practice-based medicine, and just-in-time fabrication as drivers behind the design, fabrication, and scaling of clinician-made solutions throughout the hospital. Results show that the presence of the Makerspace significantly contributed to the hospital’s nimble and proactive response to the pandemic, emphasizing the need for transformative approaches that embrace innovation, collaboration, knowledge-sharing, and recognition of clinician-led innovations to advance patient care.

PERIODONTITIS AND CARDIOVASCULAR DISEASE AS A SHARED CLINICAL CHALLENGE IN PATIENT CARE

Cardiovascular disease (CVD) remains the leading cause of death, accounting for approximately one-third of all deaths worldwide. The primary aim of the study is to find the link between periodontitis and cardiovascular disease as a shared clinical challenge in patient care. This retrospective observational cohort study was conducted in Jinnah Medical and Dental College Karachi from May 2023 to August 2023. The study included a total of 230 patients from a diverse patient population. Patient data were collected meticulously through a comprehensive dental and medical records review. A total of 230 patients were included in this retrospective observational cohort study. Patient demographics, including age and gender, were documented to provide an overview of the study population. The study included 230 patients with a mean age of 45. 55% of the participants were male, and 45% were female. Based on clinical measurements, 35% of patients showed mild periodontitis, 45% moderate periodontitis, and 20% severe periodontitis. Radiographic evidence of bone loss was observed in 60% of the patients. 40% of the patients had a documented history of cardiovascular diseases, including coronary artery disease, myocardial infarction, stroke, or hypertension.It is concluded that a significant association between periodontitis and cardiovascular diseases has been found. While the precise mechanisms remain fully understood, these findings underscore the importance of comprehensive healthcare that considers both oral and cardiovascular health.

Prediction of stress-related gastrointestinal bleeding in patients with aneurysmal subarachnoid hemorrhage using caudate Hounsfield unit value in ASPECT score.

Stress-related gastrointestinal bleeding (SRGB) is one of the major complications after aneurysmal subarachnoid hemorrhage (aSAH), and it can present challenges in patient care and treatment. The aim of this study was to explore the clinical significance of the caudate Hounsfield unit (HU) value in the Alberta Stroke Program Early CT (ASPECT) score for predicting SRGB in patients with aSAH. We retrospectively analyzed the data of 531 aSAH patients admitted to our institution between 2019 and 2022. Potential predictors of SRGB were identified using multivariate Cox regression analysis. We used a restricted cubic spline (RCS) to evaluate whether there is a nonlinear relationship between the right caudate HU value and SRGB. MaxStat analysis (titled as maximally selected rank statistics) was performed to identify the optimal cutoff point for the right caudate HU value. Another Kaplan-Meier method with the log-rank test was used to analyze the right caudate HU value in predicting the occurrence of SRGB. The incidence rate of SRGB was 17.9%. In the multivariate Cox regression analysis, the right caudate HU value was an independent predictor of SRGB [Hazard ratio (HR) = 0.913; 95% confidence interval (CI): 0.847-0.983, and p = 0.016]. The RCS indicated that the incidence of developing SRGB reduces with increasing right caudate HU values (nonlinear p = 0.78). The optimal cut-off value of the right caudate HU was 25.1. Among aSAH patients, lower right caudate HU values indicated a higher risk of developing SRGB. Our findings provide further evidence for the relationship between the gastrointestinal system and the brain.

Facilitating and Preventing Factors of Tracheostomy Patient Care by Home Caregivers: A Qualitative Study

Background: The unstable condition of tracheostomy patients and the lack of support resources for patients and their families during discharge is the biggest challenge, especially for their home and non-professional caregivers. The present study aimed to identify the factors affecting the care of tracheostomy patients provided by home caregivers. Materials and Methods: This qualitative research was conducted from September 2018 to December 2019 using the content analysis method and interviews with nine home caregivers and one professional caregiver in Lorestan Province, Iran. The required data were collected by holding in-depth semi-structured interviews and continued until reaching data saturation. Simultaneously, the gathered data were analyzed using the 5-step approach of Graneheim and Lundman (2004). Results: The results led to the extraction of 2 themes of preventing and facilitating care factors, 7 categories, and 21 subcategories. The categories related to the theme (preventing factors) of patient care challenges included neglecting the caring role of informal caregivers by the healthcare system, interaction challenges, the high pressure of caregiving, and lack of trust. The categories related to the facilitating factors theme were the experience of the care facilitating over time, the intensification of care with the aim of prevention, and hope and inner satisfaction underlying the care. Conclusion: The challenges of the family's lack of readiness to accept the new role, the exhausting nature of caregiving, and the caregivers’ lack of skills, and as a result, the imposition of a burden of caregiving, and the emergence of harmful consequences for them in various dimensions, the existence of non-governmental organizations that aim to continue to care for these patients and support their families seems necessary. With support systems and gaining experience over time, the care transition process is facilitated.

Revising Reflection Assignments to Align With Clinical Judgment Measurement Model Language: Maximizing Critical Thinking, Feedback, and Measurement in Simulation.

Student reflection stimulates self-awareness, deep learning, insight into patient care challenges, and professional role development. As such, reflection assignments are an ideal target for revision using language associated with the steps of the clinical judgment measurement model (CJMM) to maximize critical thinking. Tanner's clinical judgment model aligns with the CJMM and underpins the curriculum in many nursing programs. Faculty used the model to update a simulation reflection assignment template, incorporating CJMM language and facilitating improved measurement of clinical judgment. Substantially improved student responses resulted during an initial quality improvement pilot study.

A Multiaxial Rehabilitation Programme for Workers with COVID-19 Sequelae Using a Conventional and Technological-Robotic Approach: The Proposal of INAIL and Fondazione Don Carlo Gnocchi.

The COVID-19 sequelae have been shown to affect respiratory and cardiological functions as well as neuro-psychological functions, and, in some cases, metabolic/nutritional aspects. The Italian National Institute for Insurance against Accidents at Work (Istituto Nazionale Assicurazione Infortuni sul Lavoro, INAIL) recorded that, until December 2022, 315,055 workers were affected by COVID-19; therefore, there is a need to identify an effective approach to treat such patients. Robotic and technological devices could be integrated into the rehabilitation programme of people with long COVID conditions. A review of the literature showed that telerehabilitation may improve functional capacity, dyspnoea, performance, and quality of life in these patients, but no studies were found evaluating the effects of robot-mediated therapy or virtual reality systems. Considering the above, Fondazione Don Carlo Gnocchi and INAIL propose a multi-axial rehabilitation for workers with COVID-19 sequelae. To accomplish this goal, the two institutions merged the epidemiological information gathered by INAIL, the expertise in robotic and technological rehabilitation of Fondazione Don Carlo Gnocchi, and the literature review. Our proposal aims to facilitate a multi-axial rehabilitation approach customized to meet the unique needs of each individual, with a particular emphasis on utilizing advanced technologies to address the current and future challenges of patient care.

Urology 2030: Why it is key to promote digitisation in urology today to maintain medical care in the future - an expert consensus

Due to demographic change associated with an increase in patient numbers as well as the existing shortage of medical personnel, the German healthcare system will face a major challenge in patient care. In order to maintain high-quality patient care at a high level, the digitisation of urology should be driven forward promptly and forcefully as digital applications such as online appointment scheduling, video consultations, digital health applications (DiGAs) and others could significantly improve treatment efficiency. The long-planned introduction of the electronic patient record (ePA) will hopefully accelerate this process, and medical online platforms could also become a permanent part of new treatment methods, which could emerge from the urgently needed structural change towards more digital medicine, including questionnaire-based telemedicine. This transformation, which, already today, is urgently needed in the healthcare system, must be demanded and promoted by service providers, but also by policymakers and administration, in order to achieve the positive development of digitisation in (urological) medicine.

Use of big data from health insurance for assessment of cardiovascular outcomes.

Outcome research that supports guideline recommendations for primary and secondary preventions largely depends on the data obtained from clinical trials or selected hospital populations. The exponentially growing amount of real-world medical data could enable fundamental improvements in cardiovascular disease (CVD) prediction, prevention, and care. In this review we summarize how data from health insurance claims (HIC) may improve our understanding of current health provision and identify challenges of patient care by implementing the perspective of patients (providing data and contributing to society), physicians (identifying at-risk patients, optimizing diagnosis and therapy), health insurers (preventive education and economic aspects), and policy makers (data-driven legislation). HIC data has the potential to inform relevant aspects of the healthcare systems. Although HIC data inherit limitations, large sample sizes and long-term follow-up provides enormous predictive power. Herein, we highlight the benefits and limitations of HIC data and provide examples from the cardiovascular field, i.e. how HIC data is supporting healthcare, focusing on the demographical and epidemiological differences, pharmacotherapy, healthcare utilization, cost-effectiveness and outcomes of different treatments. As an outlook we discuss the potential of using HIC-based big data and modern artificial intelligence (AI) algorithms to guide patient education and care, which could lead to the development of a learning healthcare system and support a medically relevant legislation in the future.

Pharmacogenetics of pain management in Zimbabwean patients with sickle cell disease.

Background: Pain is a common cause of hospitalization in sickle cell disease (SCD) patients. Failure to effectively control pain remains a challenge in patient care. Materials & methods: The authors conducted a cross-sectional study to determine the effect of CYP2D6 and UGT2B7 polymorphisms on pain management in 106 Zimbabwean SCD patients. Participant information was collected on a questionnaire. Genotyping was conducted using the GenoPharm® pharmacogenomics open array panel containing CYP2D6 and UGT genetic variants implicated in opioid response. Results: The reduced function alleles CYP2D6*17 and *29 had high frequencies of 15.9% and 12.9%, respectively. UGT2B7 rs73823859 showed a statistically significant correlation with pain levels (p=0.0454). Conclusion: This study demonstrated the role of UGT2B7 polymorphism in SCD patient pain management.

Abstract 5370: New oncology target identification and validation platform combining artificial intelligence and preclinical pharmacology

Abstract Despite major advances in cancer therapy in the last decades, treatment resistance can develop over time. Precision medicine allows for the successful implementation of targeted therapies and stratification of patients, but treatment resistance remains a major obstacle in patient management. The identification and validation of new targets associated with cancer resistance remains a major challenge. The great diversity of molecular mechanisms involved in treatment resistance phenomena, whether intrinsic (de novo or primary) or acquired (secondary), constitutes a real therapeutic challenge for patient care. A better understanding of resistance mechanisms would allow to explore new therapeutic strategies to circumvent these phenomena in different types of cancer. The OncoSNIPE® project was developed in this context as part of a multicenter and collaborative clinical study (NCT04548960) in more than 800 chemo-naive adult patients. The objective of this project was to identify early and/or late markers of treatment resistance in three different pathologies for which resistance problems are encountered: triple negative breast cancer (TNBC) or luminal B, locally advanced or metastatic non-small cell lung cancer (NSCLC) and pancreatic ductal adenocarcinoma (PDAC). The program included traditional clinical and whole exome sequencing (WES) monitoring of patient biopsies (Exom-seq and RNA-seq) at diagnosis and relapse, monitoring of blood markers (RNA-seq and Proteomics – Cytokine) at diagnosis, and the evaluation of best therapeutic responses and relapse. The program used bioinformatics, artificial intelligence, statistical learning and semantic enrichment approaches to discover the diversity of mechanisms involved in these resistances and to identify new therapeutic targets, through hetero-modal data including clinical, genomic, transcriptomic, immunological and radiomic dimensions. Subsequently, a specific flowchart for target validation was applied to the resulting list, considering the target's developmental potential, its essentiality, prior knowledge (database mining) and home-made score of the link between the target and the disease. Finally, new targets were prioritized using weighting parameter and heuristic approximation based on the Crank algorithm. Experimental work on multiple targets began in the laboratory, initially in vitro, using 2D and 3D cell culture (including cells from patient-derived xenografts) and molecular interference. A wide variety of intrinsic or acquired molecular mechanisms involved in treatment resistance are being evaluated as candidates for diagnostic and therapeutic development. Citation Format: Sebastien Vachenc, Nicolas Ancellin, Didier Grillot, Kenji Shoji, Joanna Giemza, Nathalie Jeanray, Leila Outemzabet, Salvatore Raieli, Lamine Toure, Olivier Duchamp, Fabrice Viviani, Philippe Genne, Jan Hoflack, Stéphane Gerart. New oncology target identification and validation platform combining artificial intelligence and preclinical pharmacology. [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 5370.

Exploring the Experiences of Nurses in Providing Care to Patients with COVID-19: A Qualitative Study in Iran.

This study aimed to explore the experiences of nurses in providing care to COVID-19 patients. This qualitative study was conducted with the content analysis approach between June and Agust 2020 in Iran. Fourteen nurses working in COVID-19 wards were selected via purposive sampling. The data were collected via semi-structured interviews and the Graneheim and Lundman content analysis method was adopted for the data analysis. The experiences of nurses in providing care to COVID-19 patients were divided into four categories "a scarcity of knowledge about COVID-19 patient care," "changes in daily life," "patient care challenges," and "occupational burnout." The results of this study can be used by managers when facing crises similar to COVID-19 so that by paying attention to the challenges of caring for patients identified in this study, they can make the necessary preparations for caring for patients during other pandemic crises and plan the necessary measures accordingly. Also, to maintain and promote the quality of nursing care, it is crucial to ensure the adequate provision of resources for patient care, such as utilizing personal protective equipment and mechanisms that offer financial and emotional support to nurses.

"More Spiritual Health Professionals Provide Different Care": A Qualitative Study in the Field of Mental Health.

In recent years, there has been an exponential increase in studies demonstrating the positive effects of the religiosity/spirituality (R/S) approach on patients' physical and mental health. In mental health units, patients want professionals to be sensitive to their spiritual and/or religious needs, which is a fundamental aspect of a holistic approach to patients. Qualitative research with an exploratory and descriptive design with an ethnographic-phenomenological approach through in-depth interviews with sixteen professionals from Spanish mental health units. There is no consensus on the definition of spirituality; however, all of them believe that R/S has a positive influence on the health of patients in coping with illness. They believe that their own R/S may interfere with the professional-patient relationship and their attention to spiritual needs. Few professionals address these needs, citing limitations such as lack of time and lack of specific training in spiritual care. More research is needed on the spiritual care of mental health professionals to define the framework, professional training, and associated challenges in the spiritual care of patients.

Genomic insights of Leclercia adecarboxylata strains linked to an outbreak in public hospitals in Mexico.

Leclercia adecarboxylata is a bacteria closely related to Escherichia coli according to its biochemical characteristics and is commonly considered non-pathogenic although a growing number of publications classify it as an emerging pathogen. Fosfomycin resistance is a common trait for L. adecarboxylata encoded by fosALA gene. To analyze genomic traits of sixteen L. adecarboxylata strains isolated from blood culture and a bottle of total parenteral nutrition. Twenty-eight L. adecarboxylata strains isolated from blood culture and a bottle of total parenteral nutrition were identified biochemically with a Vitek ® automated system. The strains were phenotyped by their growth on Eosin Methylene Blue agar or MacConkey agar plates. Additionally, Pulsed field gel electrophoresis (PFGE) was performed to establish the clonal relationship. The genomic DNA of sixteen strains was obtained using a Qubit ® dsDNA HS Assay Kit and sequenced on an Illumina ® MiSeq instrument. Draft genomes were assembled using PROKKA and Rast. Assemblies were submitted to Resfinder and PathogenFinder from the Center for Genomic Epidemiology in order to find resistance genes and pathogenic potential. IslandViewer4 was also used to find Pathogenicity and Phage Islands. For identification of the fosA gene, manual curation and Clustal analysis was performed. A novel FosA variant was identified. Finally, phylogenetic analysis was performed using VAMPhyRE software and Mega X. In this paper, we report the genomes of sixteen strains of Leclercia adecarboxylata causing an outbreak associated with parenteral nutrition in public hospitals in Mexico. The genomes were analyzed for genetic determinants of virulence and resistance. A high pathogenic potential (pathogenicity index 0.82) as well as multiple resistance genes including carbapenemics, colistin and efflux pumps were determined. Based on sequence analysis, a new variant of the fosALA gene was described. Finally, the outbreak was confirmed by establishing the clonal relationship among the sixteen genomes obtained. Commensal strains of L. adecarboxylata may acquire genetic determinants that provide mechanisms of host damage and go unnoticed in clinical diagnosis. L. adecarboxylata can evolve in a variety of ways including the acquisition of resistance and virulence genes representing a therapeutic challenge in patient care.

Ethical Dimensions in Contemporary Medical Practices: A Systematic Review and Analysis of Diverse Perspectives

Objective: This systematic review and analysis aim to comprehensively explore diverse ethical perspectives within contemporary medical practices. Acknowledging the complexity of ethical considerations in medicine influenced by cultural, socio-economic, and legal factors, the objective is to synthesize insights from various studies and delve into key themes such as patient autonomy, informed consent, healthcare equity, and the ethical implications of emerging technologies. Methodology: Adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines 2020, this analysis systematically reviewed scholarly articles focusing on ethical considerations within modern medical practices from 2020 to 2023. A thorough screening process, based on specific Medical Subject Headings (MeSH) terms, was conducted in major databases (PubMed, Scopus, Web of Knowledge, and Google Scholar). Eleven relevant studies were included, representing diverse perspectives and ethical frameworks. Result: The systematic study selection process identified 11 relevant studies from an initial pool of 297 records. These studies covered a range of topics, including parental decision-making for adolescents with mental health issues, the legalization of medical cannabis, challenges in patient care during the COVID-19 pandemic and medical education ethics. The included studies were subjected to a meticulous evaluation of their characteristics, outcomes, and limitations. The findings contribute valuable insights into the multifaceted ethical dimensions of contemporary medical practices. Conclusion: This systematic review and analysis provide a comprehensive overview of diverse ethical perspectives inherent in contemporary medical practices. While recognizing the complexity of medical ethics, influenced by various factors, the study identifies patterns, gaps and divergent viewpoints within the selected studies. The analysis aims to inform practitioners, policymakers, and scholars engaged in ethical decision-making in healthcare, fostering a more informed and ethically robust approach to modern medical practices. Despite the limitations in some studies, the findings contribute to the ongoing discourse on medical ethics and highlight the need for further research and dialogue to address evolving ethical challenges in healthcare.