This paper discusses the balance between artistry and science in the landscape design of memorial gardens, which relies on visual quality prediction. This paper introduces the theoretical basis of vision quality prediction, including the definition, evaluation method and prediction model of vision quality. This paper analyzes the artistry and scientificity of memorial garden landscape design. It expounds that artistry emphasizes the designer’s innovation and aesthetic expression, while scientificity focuses on the feasibility and practicability of design. Finding a balance between the two, so that the design can meet aesthetic and practical needs is an essential challenge for designers. The application of visual quality prediction in memorial garden landscape design and its influence on the balance between artistic and scientific design are discussed in detail. It is found that visual quality prediction can provide a scientific basis for designers to make decisions and help them create high-quality visual effects while meeting practical needs. The research results are summarized, and the future research direction is prospected. With the development of computer technology and artificial intelligence technology, visual quality prediction will play an increasingly important role in landscape design.