Central Regions Of Clusters Research Articles

Properties of star-forming galaxies in a cluster and its surrounding structure at

We conduct a narrow-band imaging survey of [OII] emitters over a 32'x23' area in and around the XMMXCS J2215.9-1738 cluster at z=1.46 with Subaru/Suprime-Cam, and select 380 [OII] emitting galaxies down to 1.4E-17 erg/s/cm2. Among them, 16 [OII] emitters in the cluster central region are confirmed by NIR spectroscopy with Subaru/MOIRCS. We find that [OII] emitters are distributed along filamentary large-scale structures around the cluster. The z'-K vs K colour-magnitude diagram shows that a significantly higher fraction of [OII] emitters is seen on the red sequence in the cluster core than in other environments we define in this paper. It is likely that these red galaxies are nearly passively evolving galaxies which host [OII] emitting AGNs, rather than dust-reddened star-forming galaxies. We argue therefore that AGN feedback may be one of the critical processes to quench star formation in massive galaxies in high density regions. We also find that the cluster has experienced high star formation activities at rates comparable to that in the field at z=1.46. In addition, a mass-metallicity relation exists in the cluster at z=1.46, which is similar to that of star-forming galaxies in the field at z~2. These results all suggest that at z~1.5 star formation activity in the cluster core becomes as high as those in low density environments and there is apparently not yet a strong environmental dependence, except for the red emitters.

RED STAR-FORMING GALAXIES AND THEIR ENVIRONMENT ATz= 0.4 REVEALED BY PANORAMIC Hα IMAGING

We present a wide-field H-alpha imaging survey of the rich cluster CL0939+4713 (Abell 851) at z=0.41 with Suprime-Cam on the Subaru Telescope, using the narrow-band filter NB921. The survey is sensitive to active galaxies with star formation rates down to ~0.3Msun/yr throughout the 27'x27' field, and we identified 445 H-alpha emitters along the large-scale structures around the cluster. Using this sample, we find that (1) the fraction of H-alpha emitters is a strong function of environment and shows a clear decline toward the cluster central region. We also find that (2) the color of H-alpha emitters is clearly dependent on environment. The majority of the H-alpha emitters have blue colors with B-I<2, but we find H-alpha emitters with red colors as well. Such red emitters are very rare in the cluster center or its immediate surrounding regions, while they are most frequently found in groups located far away from the cluster center. These groups coincide with the environment where a sharp transition in galaxy color distribution is seen. This may suggest that dusty star formation activity tends to be involved in galaxy truncation processes that are effective in groups, and it is probably related to the "pre-processing" that generates present-day cluster S0 galaxies. Finally, we confirm that (3) the mass-normalized integrated star formation rate in clusters (i.e. the total star formation rate within 0.5xR200 from the cluster center divided by the cluster dynamical mass) rapidly increases with look-back time following approximately ~(1+z)^6, and it is also correlated with the cluster mass.

Quantifying galactic morphological transformations in the cluster environment

We study the effects of the cluster environment on galactic morphology by defining a dimensionless angular momentum parameter $\lambda_{d}$, to obtain a quantitative and objective measure of galaxy type. The use of this physical parameter allows us to take the study of morphological transformations in clusters beyond the measurements of merely qualitative parameters, e.g. S/E ratios, to a more physical footing. To this end, we employ an extensive Sloan Digital Sky Survey sample (Data Release 7), with galaxies associated with Abell galaxy clusters. The sample contains 121 relaxed Abell clusters and over 51,000 individual galaxies, which guarantees a thorough statistical coverage over a wide range of physical parameters. We find that the median $\lambda_{d}$ value tends to decrease as we approach the cluster center, with different dependences according to the mass of the galaxies and the hosting cluster; low and intermediate mass galaxies showing a strong dependence, while massive galaxies seems to show, at all radii, low $\lambda_{d}$ values. By analysing trends in $\lambda_{d}$ as functions of the nearest neighbour environment, clustercentric radius and velocity dispersion of clusters, we can identify clearly the leading physical processes at work. We find that in massive clusters ($\sigma>700$ km/s), the interaction with the cluster central region dominates, whilst in smaller clusters galaxy-galaxy interactions are chiefly responsible for driving galactic morphological transformations.

Nuclei of early-type dwarf galaxies: insights from stellar populations★

We present a comprehensive analysis of the spatially resolved stellar population properties of 26 early-type dwarf galaxies (dEs) in the Virgo cluster. Using Lick/IDS absorption line indices we derive simple stellar population (SSP) equivalent age, metallicity and [α/Fe] abundance ratio. In particular, we focus on the comparison of the stellar populations between the central nucleus and the surrounding galactic main body. The stellar populations of the nuclei are, for most dEs, significantly younger than those of the respective galactic main bodies, with an average difference of 3.5 Gyr. We find only five dEs with significantly older nuclei than their galactic main bodies. Furthermore, we observe most dE nuclei to be more metal rich compared to their host galaxies. These age and metallicity behaviours are shown by almost all dEs brighter than Mr=−17 mag. The metallicity of both nuclei and galactic main bodies correlates with the total luminosity of the dEs. However, the metallicity of the nuclei covers a larger range (+0.18 to −1.22 dex) than that of the galactic main bodies, which all have subsolar metallicity. The ages of dE nuclei show a statistically significant correlation with the local projected galaxy density within the cluster, such that younger ages are predominantly observed outside of the high-density central cluster region. The α-element abundance ratios are consistent with solar for both nuclei and galactic main bodies. We also examine the presence of radial gradients in the SSP parameters for a subset of 13 dEs (up to 1.2 kpc or 15 arcsec radius). We notice two different types of gradients, namely smooth profiles that include the nucleus, and profiles where a break occurs between the nucleus and the rest of the galaxy. Nevertheless, an overall trend of increasing age and decreasing metallicity with radius exists, consistent with earlier studies. The α-abundance ratio as function of radius is consistent with no gradient. Possible formation scenarios for the nuclei of dEs are discussed. The young and metal-enhanced population of nuclei suggests that these might have formed at later epochs, or the termination of star formation activity in the nuclei might have occurred relatively late, perhaps due to continuous infall of gas into the central potential well. Our stellar population analysis suggests that the merging of globular clusters is not an appropriate scenario for the formation of most dE nuclei, at least not for the brighter dEs. We speculate that there might be different formation processes which are responsible for the formation of dEs and their nuclei depending on their luminosity.

Searching for the missing baryons in clusters

Observations of clusters of galaxies suggest that they contain fewer baryons (gas plus stars) than the cosmic baryon fraction. This "missing baryon" puzzle is especially surprising for the most massive clusters, which are expected to be representative of the cosmic matter content of the universe (baryons and dark matter). Here we show that the baryons may not actually be missing from clusters, but rather are extended to larger radii than typically observed. The baryon deficiency is typically observed in the central regions of clusters (∼0.5 the virial radius). However, the observed gas-density profile is significantly shallower than the mass-density profile, implying that the gas is more extended than the mass and that the gas fraction increases with radius. We use the observed density profiles of gas and mass in clusters to extrapolate the measured baryon fraction as a function of radius and as a function of cluster mass. We find that the baryon fraction reaches the cosmic value near the virial radius for all groups and clusters above ∼5 x 10(13)h(-1)(72)M. This suggests that the baryons are not missing, they are simply located in cluster outskirts. Heating processes (such as shock-heating of the intracluster gas, supernovae, and Active Galactic Nuclei feedback) likely contribute to this expanded distribution. Upcoming observations should be able to detect these baryons.

Cluster galaxies in XMMU J2235-2557: galaxy population properties in most massive environments atz ~ 1.4

We present a multi-wavelength study of galaxy populations in the core of the massive, X-ray luminous cluster XMMU J2235 at z=1.39, based on VLT and HST optical and near-infrared photometry. Luminosity functions in the z, H, and Ks bands show a faint-end slope consistent with being flat, and a characteristic magnitude M* close to passive evolution predictions of M* of local massive clusters, with a formation redshift z>2. The color-magnitude and color-mass diagrams show evidence of a tight red sequence of massive galaxies, with overall old stellar populations, generally early-type morphology, typically showing early-type spectral features and rest-frame far-UV emission consistent with very low star formation rates (SFR<0.2Msun/yr). Star forming spectroscopic members, with SFRs of up to ~100Msun/yr, are all located at clustercentric distances >~250kpc, with the central cluster region already appearing effectively quenched. Massive galaxies in the core of this cluster appear to be in an advanced evolutionary stage in terms of both star formation and mass assembly. The high-mass end of the galaxy stellar mass function is essentially already in place, and the stellar mass fraction estimated within r500 (~1%, Kroupa IMF) is already similar to that of local massive clusters. On the other hand, morphological analysis of the massive red sequence galaxies suggests that they are smaller than similarly massive local early-types. While possibly affected by systematics and biases, this result might imply that, in spite of the overall early assembly of these sources, their evolution is not complete, and processes like minor (and likely dry) merging might still shape their structural properties to resemble those of their local counterparts, without substantially affecting their stellar mass or host stellar populations.[abridged]

Biases in hydrostatic mass profiles introduced by hot gas substructures: Chandra study of four galaxy clusters

By analyzing the azimuthal variations of total gravitating mass profiles in the central 300 h−171 kpc regions of four galaxy clusters with Chandra data, we find that the azimuthally-averaged mass profiles may have been systematically underestimated by 16+9−8% at 1σ significance in the 50–100 h−171 kpc regions, probably due to the prevailing existence of 2-D hot gas substructures in 100–300 h−171 kpc. The mass biases become negligible (−7+11−9%) at > 150 h−171 kpc. We confirm the results that the gas temperature maps can be used to probe the departure from hydrostatic equilibrium and help quantify the systematic biases in X-ray mass measurements in the central regions of clusters.

Ram pressure stripping in a galaxy formation model - I. A novel numerical approach

We develop a new numerical approach to describe the action of ram pressure stripping (RPS) within a semi-analytic model of galaxy formation and evolution which works in combination with non-radiative hydrodynamical simulations of galaxy clusters. The new feature in our method is the use of the gas particles to obtain the kinematical and thermodynamical properties of the intragroup and intracluster medium (ICM). This allows a self-consistent estimation of the RPS experienced by satellite galaxies. We find that the ram pressure (RP) in the central regions of clusters increases approximately one order of magnitude between z = 1 and 0, consistent with the increase in the density of the ICM. The mean RP experienced by galaxies within the virial radius increases with decreasing redshift. In clusters with virial masses M_vir ~10^15 h^-1 M_Sun, over 50 per cent of satellite galaxies have experienced RP ~10^(-11) h^2 dyn cm^-2 or higher for z <= 0.5. In smaller clusters (M_vir ~10^14 h^-1 M_Sun) the mean RP are approximately one order of magnitude lower at all redshifts. RPS has a strong effect on the cold gas content of galaxies for all cluster masses. At z = 0, over 70 per cent of satellite galaxies within the virial radius are completely depleted of cold gas. For the more massive clusters the fraction of depleted galaxies is already established at z ~ 1, whereas for the smaller clusters this fraction increases appreciably between z = 1 and 0. This indicates that the rate at which the cold gas is stripped depends on the virial mass of the host cluster. Compared to our new approach, the use of an analytic profile to describe the ICM results in an overestimation of the RP larger than 50 per cent for z >= 0.5.

The observed growth of massive galaxy clusters - II. X-ray scaling relations

(Abridged) This is the second in a series of papers in which we derive simultaneous constraints on cosmology and X-ray scaling relations using observations of massive, X-ray flux-selected galaxy clusters. The data set consists of 238 clusters drawn from the ROSAT All-Sky Survey with 0.1-2.4 keV luminosities >2.5e44 erg/second, and incorporates extensive follow-up observations using the Chandra X-ray Observatory. Our analysis accounts self-consistently for all selection effects, covariances and systematic uncertainties. Here we describe the reduction of the follow-up X-ray observations, present results on the cluster scaling relations, and discuss their implications. Our constraints on the luminosity-mass and temperature-mass relations, measured within r_500, lead to three important results. First, the data support the conclusion that excess heating of the intracluster medium has altered its thermodynamic state from that expected in a simple, gravitationally dominated system; however, this excess heating is primarily limited to the central regions of clusters (r<0.15r_500). Second, the intrinsic scatter in the center-excised luminosity-mass relation is remarkably small, being undetected at the <10% level in current data; for the hot, massive clusters under investigation, this scatter is smaller than in either the temperature-mass or Y_X-mass relations (10-15%). Third, the evolution with redshift of the scaling relations is consistent with the predictions of simple, self-similar models of gravitational collapse, indicating that the mechanism responsible for heating the central regions of clusters was in operation before redshift 0.5 (the limit of our data) and that its effects on global cluster properties have not evolved strongly since then.

REMOVING COOL CORES AND CENTRAL METALLICITY PEAKS IN GALAXY CLUSTERS WITH POWERFUL ACTIVE GALACTIC NUCLEUS OUTBURSTS

Recent X-ray observations of galaxy clusters suggest that cluster populations are bimodally distributed according to central gas entropy and are separated into two distinct classes: cool core (CC) and non-cool core (NCC) clusters. While it is widely accepted that active galactic nucleus (AGN) feedback plays a key role in offsetting radiative losses and maintaining many clusters in the CC state, the origin of NCC clusters is much less clear. At the same time, a handful of extremely powerful AGN outbursts have recently been detected in clusters, with a total energy ∼1061–1062 erg. Using two-dimensional hydrodynamic simulations, we show that if a large fraction of this energy is deposited near the centers of CC clusters, which is likely common due to dense cores, these AGN outbursts can completely remove CCs, transforming them to NCC clusters. Our model also has interesting implications for cluster abundance profiles, which usually show a central peak in CC systems. Our calculations indicate that during the CC to NCC transformation, AGN outbursts efficiently mix metals in cluster central regions and may even remove central abundance peaks if they are not broad enough. For CC clusters with broad central abundance peaks, AGN outbursts decrease peak abundances, but cannot effectively destroy the peaks. Our model may simultaneously explain the contradictory (possibly bimodal) results of abundance profiles in NCC clusters, some of which are nearly flat, while others have strong central peaks similar to those in CC clusters. A statistical analysis of the sizes of central abundance peaks and their redshift evolution may shed interesting insights on the origin of both types of NCC clusters and the evolution history of thermodynamics and AGN activity in clusters.

HYDRODYNAMICAL SIMULATIONS OF GALAXY CLUSTERS WITHGALCONS

We present our recently developed {\em galcon} approach to hydrodynamical cosmological simulations of galaxy clusters - a subgrid model added to the {\em Enzo} adaptive mesh refinement code - which is capable of tracking galaxies within the cluster potential and following the feedback of their main baryonic processes. Galcons are physically extended galactic constructs within which baryonic processes are modeled analytically. By identifying galaxy halos and initializing galcons at high redshift ($z \sim 3$, well before most clusters virialize), we are able to follow the evolution of star formation, galactic winds, and ram-pressure stripping of interstellar media, along with their associated mass, metals and energy feedback into intracluster (IC) gas, which are deposited through a well-resolved spherical interface layer. Our approach is fully described and all results from initial simulations with the enhanced {\em Enzo-Galcon} code are presented. With a galactic star formation rate derived from the observed cosmic star formation density, our galcon simulation better reproduces the observed properties of IC gas, including the density, temperature, metallicity, and entropy profiles. By following the impact of a large number of galaxies on IC gas we explicitly demonstrate the advantages of this approach in producing a lower stellar fraction, a larger gas core radius, an isothermal temperature profile in the central cluster region, and a flatter metallicity gradient than in a standard simulation.

A NEW MEASUREMENT OF THE BULK FLOW OF X-RAY LUMINOUS CLUSTERS OF GALAXIES

We present new measurements of the large-scale bulk flows of galaxy clusters based on 5-year WMAP data and a significantly expanded X-ray cluster catalogue. Our method probes the flow via measurements of the kinematic Sunyaev-Zeldovich (SZ) effect produced by the hot gas in moving clusters. It computes the dipole in the cosmic microwave background (CMB) data at cluster pixels, which preserves the SZ component while integrating down other contributions. Our improved catalog of over 1,000 clusters enables us to further investigate possible systematic effects and, thanks to a higher median cluster redshift, allows us to measure the bulk flow to larger scales. We present a corrected error treatment and demonstrate that the more X-ray luminous clusters, while fewer in number, have much larger optical depth, resulting in a higher dipole and thus a more accurate flow measurement. This results in the observed correlation of the dipole derived at the aperture of zero monopole with the monopole measured over the cluster central regions. This correlation is expected if the dipole is produced by the SZ effect and cannot be caused by unidentified systematics (or primary cosmic microwave background anisotropies). We measure that the flow is consistent with approximately constant velocity out to at least 800 Mpc. The significance of the measured signal peaks around 500 Mpc, most likely because the contribution from more distant clusters becomes progressively more diluted by the WMAP beam. We can, however, at present not rule out that these more distant clusters simply contribute less to the overall motion.

High star formation activity in the central region of a distant cluster atz= 1.46

We present an unbiased deep [OII] emission survey of a cluster XMMXCS J2215.9-1738 at z=1.46, the most distant cluster to date with a detection of extended X-ray emission. With wide-field optical and near-infrared cameras (Suprime-Cam and MOIRCS, respectively) on Subaru telescope, we performed deep imaging with a narrow-band filter NB912 (lambda_c=9139A, Delta_lambda=134A) as well as broad-band filters (B, z', J and Ks). From the photometric catalogues, we have identified 44 [OII] emitters in the cluster central region of 6'x6' down to a dust-free star formation rate of 2.6 Msun/yr (3 sigma). Interestingly, it is found that there are many [OII] emitters even in the central high density region. In fact, the fraction of [OII] emitters to the cluster members as well as their star formation rates and equivalent widths stay almost constant with decreasing cluster-centric distance up to the cluster core. Unlike clusters at lower redshifts (z<1) where star formation activity is mostly quenched in their central regions, this higher redshift 2215 cluster shows its high star formation activity even at its centre, suggesting that we are beginning to enter the formation epoch of some galaxies in the cluster core eventually. Moreover, we find a deficit of galaxies on the red sequence at magnitudes fainter than ~M*+0.5 on the colour-magnitude diagram. This break magnitude is brighter than that of lower redshift clusters, and it is likely that we are seeing the formation phase of more massive red galaxies in the cluster core at z~1. These results may indicate inside-out and down-sizing propagation of star formation activity in the course of cluster evolution.

Stellar interactions in dense and sparse star clusters

Stellar encounters potentially affect the evolution of the protoplanetary discs in the Orion Nebula Cluster (ONC). However, the role of encounters in other cluster environments is less known. We investigate the effect of the encounter-induced disc-mass loss in different cluster environments. Starting from an ONC-like cluster we vary the cluster size and density to determine the correlation of collision time scale and disc-mass loss. We use the NBODY6++ code to model the dynamics of these clusters and analyze the effect of star-disc encounters. We find that the disc-mass loss depends strongly on the cluster density but remains rather unaffected by the size of the stellar population. The essential outcome of the simulations are: i) Even in clusters four times sparser than the ONC the effect of encounters is still apparent. ii) The density of the ONC itself marks a threshold: in less dense and less massive clusters it is the massive stars that dominate the encounter-induced disc-mass loss whereas in denser and more massive clusters the low-mass stars play the major role for the disc mass removal. It seems that in the central regions of young dense star clusters -- the common sites of star formation -- stellar encounters do affect the evolution of the protoplanetary discs. With higher cluster density low-mass stars become more heavily involved in this process. This finding allows for the extrapolation towards extreme stellar systems: in case of the Arches cluster one would expect stellar encounters to destroy the discs of most of the low- and high-mass stars in several hundred thousand years, whereas intermediate mass stars are able to retain to some extant their discs even under these harsh environmental conditions.

Methionine oxidation stabilizes non-toxic oligomers of α-synuclein through strengthening the auto-inhibitory intra-molecular long-range interactions

Oxidative stress and aggregation of the presynaptic protein α-synuclein (α-Syn) are implied in the pathogenesis of Parkinson's disease and several other neurodegenerative diseases. Various posttranslational modifications, such as oxidation, nitration and truncation, have significant effects on the kinetics of α-Syn fibrillation in vitro. α-Syn is a typical natively unfolded protein, which possesses some residual structure. The existence of long-range intra-molecular interactions between the C-terminal tail (residues 120–140) and the central part of α-Syn (residues 30–100) was recently established (Bertoncini et al. (2005) Proc Natl Acad Sci U S A 102, 1430–1435). Since α-Syn has four methionines, two of which (Met 1 and 5) are at the N-terminus and the other two (Met 116 and 127) are in the hydrophobic cluster at the C-terminus of protein, the perturbation of these residues via their oxidation represents a good model for studying the effect of long-range interaction on α-Syn fibril formation. In this paper we show that Met 1, 116, and 127 are more protected from the oxidation than Met 5 likely due to the residual structure in the natively unfolded α-Syn. In addition to the hydrophobic interactions between the C-terminal hydrophobic cluster and hydrophobic central region of α-Syn, there are some long-range electrostatic interactions in this protein. Both of these interactions likely serve as auto-inhibitors of α-Syn fibrillation. Methionine oxidation affects both electrostatic and hydrophobic long-range interactions in α-Syn. Finally, oxidation of methionines by H 2O 2 greatly inhibited α-Syn fibrillation in vitro, leading to the formation of relatively stable oligomers, which are not toxic to dopaminergic and GABAergic neurons.

Models of particle acceleration in galaxy clusters by MHD turbulence

AbstractPresent radio data provide indirect evidence that diffuse radio emission in the central cluster regions may originate from turbulent-acceleration of relativistic particles. I was invited to discuss models of particle acceleration by MHD turbulence in clusters and in these pages I briefly touch the main points of my talk.

Constraining relativistic protons and magnetic fields in galaxy clusters through radio and γ-ray observations: the case of A2256

Giant radio halos are the most relevant examples of diffuse synchrotron emission from galaxy clusters. A number of these sources have very steep spectrum, with spectral index $\alpha \geq 1.5-1.6$ ($F(\nu) \propto \nu^{-\alpha}$), and are ideal targets to test current models for the origin of the relativistic particles. A2256 hosts the nearest radio halo with very steep spectrum, with $\alpha =1.61$, and a very large population of relativistic protons in the cluster would be necessary to explain the halo as due to synchrotron emission from secondary particles. In this case the 0.1-1 GeV $\gamma$--ray luminosity is expected 10-20 times larger than that of clusters hosting radio halos with similar radio power at GHz frequencies but with spectra more typical of the presently observed halo population, $\alpha \sim 1.2$. Under these assumptions incoming FERMI/GLAST observations are expected to detect A2256, provided that the magnetic field in the central cluster region is $\leq$10-15 $\mu$G. We show that this will allow for a prompt test of hadronic models for the origin of radio halos, and for complementary constraints on both the cluster magnetic field and the physics of particle acceleration mechanisms.

On the evolution of giant radio halos and their connection with cluster mergers

Giant radio halos are diffuse, Mpc-scale, synchrotron sources located in the central regions of galaxy clusters and provide the most relevant example of cluster non-thermal activity. Radio and X-ray surveys allow to investigate the statistics of halos and may contribute to constrain their origin and evolution. We investigate the distribution of clusters in the plane X-ray (thermal, L_X) vs synchrotron (P_{1.4})luminosity, where clusters hosting giant radio halos trace the P_{1.4}--L_X correlation and clusters without radio halos populate a region that is well separated from that spanned by the above correlation. The connection between radio halos and cluster mergers suggests that the cluster Mpc-scale synchrotron emission is amplified during these mergers and then suppressed when clusters become more dynamically relaxed. In this context, by analysing the distribution in the P_{1.4}--L_X plane of clusters from X-ray selected samples with adequate radio follow up, we constrain the typical time-scale of evolution of diffuse radio emission in clusters and discuss the implications for the origin of radio halos. We conclude that cluster synchrotron emission is suppressed (and amplified) in a time-scale significantly smaller than 1 Gyr. We show that this constraint appears difficult to reconcile with the hypothesis that the halo's radio power is suppressed due to dissipation of magnetic field in galaxy clusters. On the other hand, in agreement with models where turbulent acceleration plays a role, present constraints suggest that relativistic electrons are accelerated in Mpc-scale regions, in connection with cluster mergers and for a time-interval of about 1 Gyr, and then they cool in a relatively small time-scale, when the hosting cluster becomes more dynamically relaxed.

Genetic diversity of capsular polysaccharide biosynthesis in Klebsiella pneumoniae clinical isolates

Klebsiella pneumoniae is an enteric pathogen causing community-acquired and hospital-acquired infections in humans. Epidemiological studies have revealed significant diversity in capsular polysaccharide (CPS) type and clinical manifestation of K. pneumoniae infection in different geographical areas of the world. We have sequenced the capsular polysaccharide synthesis (cps) region of seven clinical isolates and compared the sequences with the publicly available cps sequence data of five strains: NTUH-K2044 (K1 serotype), Chedid (K2 serotype), MGH78578 (K52 serotype), A1142 (K57 serotype) and A1517. Among all strains, six genes at the 5' end of the cps clusters that encode proteins for CPS transportation and processing at the bacterial surface are highly similar to each other. The central region of the cps gene clusters, which encodes proteins for polymerization and assembly of the CPS subunits, is highly divergent. Based on the collected sequence, we found that either the wbaP gene or the wcaJ gene exists in a given K. pneumoniae strain, suggesting that there is a major difference in the CPS biosynthesis pathway and that the K. pneumoniae strains can be classified into at least two distinct groups. All isolates contain gnd, encoding gluconate-6-phosphate dehydrogenase, at the 3' end of the cps gene clusters. The rmlBADC genes were found in CPS K9-positive, K14-positive and K52-positive strains, while manC and manB were found in K1, K2, K5, K14, K62 and two undefined strains. Our data indicate that, while overall genomic organization is similar between different pathogenic K. pneumoniae strains, the genetic variation of the sugar moiety and polysaccharide linkage generate the diversity in CPS molecules that could help evade host immune attack.

FUV Emission in Cool-Core Clusters

AbstractFar ultraviolet (FUV) emission is observed in the central regions of cool-core clusters with the Hubble Space Telescope (HST). It is traced out to 20 kpc from the nuclei of the brightest cluster galaxies and found to be distributed in clumps and filaments, as shown in Figure 1. The FUV emission matches the global structure of the ionized gas nebulae. If produced by stars, this emission can account for the ionization but not the temperature of the gas (Voit &amp; Donahue 1997; Oonk et al. in preparation).