[ILLUSTRATION OMITTED] The son of peasants, Professor Zhou Yiqing was born in 1929. He joined the Eighth Route Army (later part of the People's Liberation Army) at the age of 16. During the Sino-Japanese War and the War of Liberation (Chinese Civil War) he served as a nurse, head of a nursing squad, assistant physician and eventually doctor-in-charge. In 1960, he graduated from the Shanghai No. 2 Military Medical University and later became a researcher at the Institute of Microbiology and Epidemiology (IME) of the Chinese Academy of Military Medical Sciences (AMMS). In April this year, Zhou Yiqing and his team won the 2009 European Inventors of the Year award (in the non-European countries category) for developing the first artemisinin-based combination therapy (ACT) for known as Coartem. He talks to reporter Cui Weiyuan about this achievement. Q: Did malaria ever affect people in China? A: Malaria was an epidemic disease in China for more than 3000 years. The symptoms were described in ancient writings. For example, Nei Jing (the Canon of Internal Medicine) described them as early as 270 BC. When the People's Republic of China was founded in 1949, malaria was endemic in two-thirds of Chinese counties, but it has not been a major public health problem since the 1980s. Q: What was your first experience of malaria? A: In the battle to cross the Yangtze River in 1949, I contracted the disease for the first time and suffered recurring bouts. No effective medicine was available. The pain left a sharp impression on me. I received an arsenic injection and, later, Atabrine (quinacrine) pills. The pills made me turn bright yellow. Although the side-effects were serious, I survived. Some female comrades suffered psychosis from drug toxicity after being treated. Q: Is that what spurred you to do research to find antimalarial drugs? A: While I worked as a battlefield doctor, one thing bothered me most: wounded soldiers begging me to save their lives because sometimes I just could not help them. I had only four years' primary school education. I vowed to improve myself. In 1960, I graduated from medical school and was assigned to become a researcher at the Chinese AMMS but was first sent to the Soviet Union for further study. Contracting malaria made me realize how bad the disease can be. However, my official participation in the research project stemmed from the Viet Nam War. When I returned from the Soviet Union in 1964, the war had broken out. I was ordered to conduct field research on tropical diseases in Viet Nam. China was supporting North Viet Nam and providing it with medical aid. Following orders, my comrades and I travelled along the Beibu (Tonkin) Gulf and through the Ho Chi Minh Trail in the jungle--it was the only way to maintain supplies for North Viet Nam because the United States of America had bombed it so intensely. We were accompanied by showers of bombs during the trip. There, I witnessed rampant malaria that reduced the combat strength by half, sometimes by up to 90% when the soldiers became ill. There was a saying, We're not afraid of American imperialists, but we are afraid of malaria, although in fact the disease took a huge toll on both sides. Later, we submitted a report to Chinas Central Military Committee, stressing the importance of developing Chinas own antimalarials. Taking our advice, the central government set up a panel of more than 500 medical military and civilian experts to develop new anti-malarial treatment for stricken soldiers. This was classified as a top secret state mission named Project 523, after the date, 23 May 1967, it was established. Q: What made you and your team think of using artemisinin to treat malaria? A: Project 523 included two groups engaged in antimalarial drug development: one to devise chemical medicines, another to examine traditional Chinese medicines. The latter group included researchers as well as traditional Chinese medicine doctors, who, as part of Chairman Mao's barefoot scheme, scoured the nation to collect folk remedies. …
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