Central Administration Research Articles

Simulators for Conversing Power to Thermal on Green Data Centers: A Review

This paper aims to help data center administrators choose thermal simulation tools, which manage thermal conduction from power for energy savings. When evaluating and suggesting data center thermal simulators for users, questions such as “What are the simulator’s differences? Are they easy to use? Which is the best choice?” are frequently asked. To answer these questions, this paper reviews the thermal simulation works for data centers in the last ten years. After that, it proposes the versatility and dexterity metrics for these simulators and discovers that it is difficult to choose them despite their similar design purpose and functions. Empowered by the survey, we claim that the widespread practice simulators still need more enhancement in data center scenarios. We back up our claim by comparing typical simulators and propose improvements to thermal simulators for future studies.

Central treatment of neuropeptide-S attenuates cognitive dysfunction and hippocampal synaptic plasticity impairment by increasing CaMKII/GluR1 in hemiparkinsonian rats.

Neuropeptide-S (NPS) has been demonstrated to mitigate learning and memory deficits in experimental models of Parkinson's Disease (PD). Despite this, the precise mechanisms through which NPS exerts its influence on cognitive functions remain to be fully unknown. This study aims to elucidate the effects of central administration of NPS on learning and memory deficits associated with an experimental rat hemiparkinsonian model, examining both electrophysiological and molecular parameters. The hemiparkinsonian model was established via stereotactic injection of 6-hydroxydopamine (6-OHDA) into the right medial forebrain bundle. Central NPS (1 nmol, icv) was administered into the lateral ventricle via a cannula for seven consecutive days following the 6-OHDA lesion. The Morris water maze and object recognition tests were used to evaluate the rat's learning and memory abilities. Long-term potentiation (LTP) recordings were conducted to assess hippocampal synaptic plasticity. Immunohistochemistry was employed to determine the expression levels of phosphorylated CaMKII (pCaMKII), GluR1, and GluR2 in the hippocampus. The 6-OHDA-induced decline in cognitive performance was significantly (p < 0.05) improved in rats that received central NPS. In 6-OHDA-lesioned rats, NPS treatment significantly (p < 0.05) enhanced the amplitude of LTP at the dentate gyrus/perforant path synapses. Furthermore, NPS significantly (p < 0.05) increased the number of pCaMKII and GluR1 immunoreactive cells in the hippocampus, which had been diminished due to 6-OHDA, except for GluR2 levels. These findings provide insight into the mechanisms by which central NPS administration enhances cognitive functions in an experimental model of PD, highlighting its potential therapeutic benefits for addressing cognitive deficits in PD.

Central administration of galanin-like peptide (GALP) causes short-term orexigenic effects in broilers: Mediatory role of NPY1 and D1 receptors

Central administration of galanin-like peptide (GALP) causes short-term orexigenic effects in broilers: Mediatory role of NPY1 and D1 receptors

DBPR116, a Prodrug of BPRMU191, in Combination with Naltrexone as a Safer Opioid Analgesic Than Morphine via Peripheral Administration.

The development of opioid analgesics with reduced adverse effects is an unmet need. In a previous study, we discovered a unique combination of BPRMU191 and morphinan antagonists that produced potent antinociception with reduced adverse effects after central administration (intrathecal or intracerebroventricular). BPRMU191/naltrexone exhibits notable in vitro and in vivo pharmacological properties. However, the poor blood-brain barrier penetrative ability of BPRMU191 restricts its clinical application. In this study, we utilized a prodrug strategy to deliver sufficient brain concentrations of BPRMU191 and selected compound 2 (DBPR116) with the best physicochemical and pharmacological properties among other in vivo active prodrugs. The in vivo pharmacological studies of compound 2/naltrexone, including thermally stimulated pain, cancer pain, constipation, sedation, psychological dependence, heart rate, and respiratory frequency measurements, demonstrated that it was a safer opioid analgesic than morphine in pain control.

The multi-dimensionality of citizen satisfaction: A conjoint experimental approach

Current research demonstrated that many factors affect public satisfaction of government services. One central challenge for scholars is that citizen satisfaction is a multi-dimensional concept, yet most empirical tests focus on a small number of factors, and do not account for the simultaneous effects of the many factors. In this study, we present a comprehensive approach that accounts for this multi-dimensionality, and views satisfaction as dependent on two categories of factors: service-specific attributes, and performance comparisons. We assess the multi-dimensional nature of citizen satisfaction with a conjoint experiment, a methodological tool that allows us to test the causal effect of multiple factors operating at the same time. We use the conjoint design to investigate citizen satisfaction from every-day government services. The findings suggest that citizen satisfaction is driven by both groups of variables. Also, we find evidence for a negativity bias in public evaluations when service-specific attributes are involved: individuals' reported satisfaction is more sensitive to negative information like higher costs or unprofessional behavior by service providers compared to positive description of these factors. At the same time, we find that factors in the performance comparisons category create more balanced effects on satisfaction with respect to the information valence. The analysis reveals the drivers of public satisfaction of government services and the importance of key factors. The use of a conjoint design provides a more appropriate tool to tackle the multi-dimensional nature of a central public administration concept of citizen satisfaction.

The shift from inpatient to outpatient settings of a surgical DRG for pediatric patients in Portugal

Abstract Background The shift of selected surgical procedures from inpatient to outpatient settings has been seen as a solution to improve health care provision. These shifts often occur under pay-for-performance schemes, pay-for-efficiency schemes, or other forms of financial incentives. For this study, we aimed to assess the effect of Decree 132/2009, implemented on February 1, 2009, which increased the relative weights of DRG 60 (“tonsillectomy and/or adenoidectomy, age &amp;lt;18”) performed in outpatient settings, thus acting as a financial incentive. Methods We performed a quasi-experimental study and employed interrupted time series (ITS) and controlled interrupted time series (CITS) designs, using monthly pediatric data provided by The Central Administration of the Health System (ACSS), with discharges between January 2006 and February 2012 (having 37 months pre- and post-decree implementation) of inpatient and outpatient episodes for DRG 60 (affected group) and DRG 163 (“hernia procedures age &amp;lt;18”, the selected control group). We used as study outcomes proportions (number of outpatient episodes divided by the sum of outpatient and inpatient episodes) to quantify increases in outpatient episodes and ratios (number of outpatient episodes divided by the number of inpatient episodes) to quantify decreases in inpatient episodes. Fourier terms were included to adjust for seasonality. Results We obtained statistically significant results only at the trend level for ratios when using the ITS model (0.01574) and for proportions only when using the CITS model (0.00310), although small non-statistically significant increases were obtained for the employed ITS as well as for the CITS design. Conclusions Decree 132/2009, which created financial incentives for the shift from inpatient to outpatient for DRG 60, showed low and non-statistically significant increases using both ITS and CITS models. Key messages • We analyzed the impact of Decree 132/2009 on the pediatric surgeries under DRG 60 performed in outpatient settings in Portugal using interrupted time series and control interrupted time series. • The decree had a small effect at the national level for DRG 60.

Mental health support for healthcare workers: what is it about governance and policy implementation

Abstract Background We adopt a health system and governance perspective to address the mental health needs of healthcare workers, considering the nature of interventions and the levels and actors involved in governance. The aim is to move the debate forward by identifying governance gaps hampering the implementation of health workforce policies and exploring strategies to effectively increase mental health support. Methods A qualitative comparative methodology is applied based on a case study design utilising a multi-level intersectoral governance matrix. The assessment matrix comprises four key categories: health policy and data, social policy and psycho-social conditions, organisation of work, and job and professional conditions. We conducted a rapid assessment of healthcare workforce developments in the European context, drawing on secondary sources and country experts. The country sample comprises Germany, Portugal, Romania, Switzerland and the United Kingdom. Results Awareness of mental health threats among healthcare workers increased, but policy discourse is driven by service delivery and labour market demands. The attention to healthcare workers’ needs is stronger on the international level especially supported by WHO action, and weakest at national/regional levels. Although organisations and professions demonstrate varying degrees of activity, their efforts are scattered and lack sustainability. Similar challenges were identified across healthcare systems, including limited action, disconnected actors, missing coordination, and a lack of attention to governance gaps and system weaknesses. Conclusions There are similar problems across countries. Mental health policy is driven by labour market needs and ignores research evidence and the individual needs. Successful mental health policy implementation needs multi-level governance and coherent coordination mechanisms, and generally greater attention to the ‘human side’ of the healthcare workforce. Speakers/Panelists Sara Alidina Central Administration of the Health System, Lisbon, Portugal Tomas Zapata WHO/Europe, Copenhagen, Denmark

The Influence of the Estrous Cycle on Neuropeptide S Receptor-Mediated Behaviors.

The Neuropeptide S receptor (NPSR) has been identified as a potential therapeutic target for anxiety and post-traumatic stress disorder. Central administration of Neuropeptide S (NPS) in male mice produces anxiolytic-like effects, hyperlocomotion, and memory enhancement. Currently, the literature is limited in the number of studies investigating the effects of NPS in female test subjects despite females facing a higher prevalence of anxiety-related pathology, as well as greater risk for adverse effects while taking psychoactive drugs. Moreover, no previous studies have considered the influence of estrous cycle on the effects of NPS. The current study investigates whether NPS-mediated behavioral phenotypes seen in males translate to females, and whether they are affected by estrous cycle stage. Female C57BL/6NCr mice were intracerebroventricularly (ICV) cannulated and underwent behavioral paradigms to test locomotion, anxiety, and memory. Estrous cycle stage was determined through examination of vaginal cytology. Our results provide evidence that NPS-mediated behaviors are influenced by the estrous cycle. Administration of NPS decreased anxiety-like behaviors more robustly when the female mice were in high estrogen stages of the estrous cycle. Therefore, the desired anxiolytic-like effects of targeting the NPSR are intact in female mice. However, these effects may to be influenced by the stage of the estrous cycle. The NPSR remains a strong potential drug target for new anxiolytic compounds and based on our initial observations further studies exploring the interaction of estrous cycle and the NPS-system are warranted. Significance Statement The neuropeptide S (NPS) receptor has been identified as a potential target for treating anxiety, a condition that is most prevalent in females. Therefore, the potential interaction of estrous cycle with the NPS-system described in the current study is an important first step in understanding the function of the NPS-system in females.

Features of the methodological views of Rizaetdin Fakhretdinov (1859-1936) on the concept of ijma‘

This article is devoted to the study of the nature and essence of one of the fundamental sources of Islamic Law - ijma‘ in the methodological views of the Qadi and the Mufti of the Central Spiritual Administration of Muslims of Russia Rizaetdin Fakhretdinov (1859-1936). The conceptual features of Fakhretdinov’s characteristic views on the nature of ijma‘, its essence, the conditions of its emergence and the specifics of its practical adaptation allowed him to raise important questions regarding the competence of participants making a consolidated decision, the categoricalness and duration of the legal force of such decisions. His views on the institutionalization of ijma‘ may indicate the presence of regional competence of ijma‘ representatives. The study of ijma‘ was carried out on the basis of an analysis of Fakhretdinov’s views with the views of classical methodologists (usuliyyun), during which the author attempts to substantiate them within the framework of Hanafi methodological thought. The article is intended to make a modest contribution to the study of the nature of ijma‘ and its role in the religious and legal life of Muslims. The nature of the article is also on rethinking the assessment of the classical heritage of fiqh, the development of a critical and practice-oriented approach in individual and collegial forms of the methodology of fatwa creation. Moreover, the paper means to attract the attention of modern researchers in the field of methodology to these issues within the Islamic Law.

China’s marine eco-environment law enforcement from the perspective of the responsibility system: Dilemmas and solutions

As the final link in promoting the construction of marine ecological civilization, the marine eco-environment law enforcement is crucial to realize the Chinese-style modernization which concerns the harmonious coexistence of humans and nature. This study examined the current state of the responsibility system of China’s marine eco-environment law enforcement through legal doctrinal analysis. Three deficiencies that are hindering the improvement of the effectiveness and efficiency of China’s marine eco-environment law enforcement were identified. Firstly, at central level, the allocation of law enforcement powers fails to reflect the principle of integrated land-sea management. There is also insufficient coordination between marine environmental law enforcement and marine resources law enforcement. Secondly, at local level, there is a lack of cross-departmental and cross-regional law enforcement collaboration mechanisms. Thirdly, regarding central-local relations, the allocation of law enforcement powers and resources is unreasonable, and there are conflicts in the management modes of law enforcement agencies. To enhance the effectiveness and efficiency of China’s marine eco-environment law enforcement, it is necessary to: (i) coordinate central law enforcement powers among different maritime-related administrations based on the principle of integrated land-sea management, and the principle of environment-resources integration; (ii) establish cross-departmental and cross-regional law enforcement collaboration mechanisms; (iii) and appropriately allocate marine eco-environment law enforcement powers between the central and local maritime-related administrations.

Digital platform work reinforcing performativity: teacher responses to work intensification explored through trace ethnography

ABSTRACT This paper critically explores how teachers’ everyday work is reconfigured through work on and around different digital platforms. In particular, it demonstrates teacher experiences of workload and work intensification and the different workarounds and adaptions to platforms done by teachers, conditioned by demands of performativity, e.g. discourses of optimising work, making visible and caring for school performances as part of a market-competitive and increasingly digitalised school system. By ethnographically tracing the digital work of six teachers in public and private upper-secondary schools through logs, follow-up interviews, observations and digital ‘go-alongs’, we show how central tasks, administration, communication and teaching are reconfigured through the distribution of work onto local-domestic and global platforms and relatively local school and national regulations. Our contribution to the discussion on platforms in education is how platforms and aligning devices and procedures reinforce performativity demands in teacher work. This reconfiguration produces tensions, interruptions and intensity peaks, often seen as work-time conflicts, but which nonetheless relate to wider, critical issues of the changing nature of teacher digital work being established in relation to the marketised and highly digitalised school.

Collecting empires: Dominik Bilimek and early subterranean zoology between politics and field research

The Moravian Cistercian monk and collector Dominik Bilimek (1813–1884) is considered one of the earliest European naturalists to conduct zoological research on subterranean fauna in Latin America. During the second French invasion of Mexico, from 1861 to 1867, he accompanied Maximilian of Habsburg, the newly enthroned emperor of Mexico, to the region. There, he explored the Grutas de Cacahuamilpa near Taxco de Alarcón, comparing its fauna to his earlier discoveries in Postojnska jama in Carniola (Slovenia). After the victory of the Mexican republican forces and Maximilian’s execution, Bilimek retained his role as curator of the emperor’s collections, which he took back with him to Europe and exhibited at Miramare Castle near Trieste. Prior to his Mexican venture, Bilimek had embraced the imperial goals and intellectual agendas of the Viennese central administration while teaching at the monarchy’s military institutes. Following the revolutions of 1848/49, extensive research undertakings—including geoscientific, biological, and archaeological surveys—were initiated to preserve the Habsburg monarchy as a supranational entity amidst internal and external crises, and to legitimize its territorial framework as both a natural and cultural unit. These developments coincided with the initial surge of zoological interest in Carniolan caves, which spurred efforts to gather similar findings in other karst regions of the monarchy. Drawing on historical sources, this article explores the intersection of political concepts and fieldwork practices in the early study of cave biology. Special attention is given to the sites, networks, and modes of collecting during this transformative period.

Interleukin-2 improves insulin sensitivity through hypothalamic sympathetic activation in obese mice

BackgroundIL-2 regulates T cell differentiation: low-dose IL-2 induces immunoregulatory Treg differentiation, while high-dose IL-2 acts as a potent activator of cytotoxic T cells and NK cells. Therefore, high-dose IL-2 has been studied for use in cancer immunotherapy. We aimed to utilize low-dose IL-2 to treat inflammatory diseases such as obesity and insulin resistance, which involve low-grade chronic inflammation.Main bodySystemic administration of low-dose IL-2 increased Treg cells and decreased inflammation in gonadal white adipose tissue (gWAT), leading to improved insulin sensitivity in high-fat diet-fed obese mice. Additionally, central administration of IL-2 significantly enhanced insulin sensitivity through the activation of the sympathetic nervous system. The sympathetic signaling induced by central IL-2 administration not only decreased interferon γ (IFNγ) + Th1 cells and the expression of pro-inflammatory cytokines, including Il-1β, Il-6, and Il-8, but also increased CD4 + CD25 + FoxP3 + Treg cells and Tgfβ expression in the gWAT of obese mice. These phenomena were accompanied by hypothalamic microgliosis and activation of pro-opiomelanocortin neurons. Furthermore, sympathetic denervation in gWAT reversed the enhanced insulin sensitivity and immune cell polarization induced by central IL-2 administration.ConclusionOverall, we demonstrated that IL-2 improves insulin sensitivity through two mechanisms: direct action on CD4 + T cells and via the neuro-immune axis triggered by hypothalamic microgliosis.

Implementation of Spiritual Therapy for Mental Disorders in Purbalingga Indonesia Mental Rehabilitation Centers

In the era of materialism, the pressures and demands in life increase various kinds of physical and psychological suffering. Mental disorders are a phenomenon that is increasing from year to year. This study describes the practice of applying spiritual therapy for mental disorders in rehabilitation homes. This research uses a qualitative approach with a case study method. The research subjects were one assistant therapist, two rehabilitation center administrators, and two patients with mental disorders. The results showed that a Kyai carried out spiritual therapy with prayer therapy methods, dhikr, rukyah syar'iyah, and drinking karomah water. Spiritual therapy is proven to heal patients and make them more independent and able to socialize with the environment.

Chronic central nervous system leptin administration attenuates kidney dysfunction and injury in a model of ischemia/reperfusion-induced acute kidney injury.

In the present study we examined whether chronic intracerebroventricular (ICV) leptin administration protects against ischemia/reperfusion (I/R)-induced acute kidney injury (AKI). Twelve-week-old male rats were implanted with an ICV cannula into the right lateral ventricle and 8-10 days after surgery, leptin (0.021 mg/hr, n=8) or saline vehicle (0.5 ml/h, n=8) was infused via osmotic minipump connected to the ICV cannula for 12 days. On day 8 of leptin or vehicle infusion, rats were submitted to unilateral ischemia/reperfusion (UIR) by clamping the left pedicle for 30 min. To control for leptin-induced reductions in food intake, the vehicle-treated group was pair-fed (UIR-PF) to match the same amount of food consumed by leptin-treated (UIR-Leptin) rats. On the 12th day of leptin or vehicle infusion (4th day after AKI), single-left kidney glomerular filtration rate (GFR) was measured, blood samples were collected to quantify white blood cells, and kidneys were collected for histological assessment of injury. UIR-Leptin treated rats showed reduced right and left kidney weights (right: 1040±24 vs. 1281±36 mg; left: 1127±71 vs. 1707±45 mg, for UIR-Leptin and UIR-PF, respectively). ICV leptin infusion improved GFR (0.50±0.06 vs. 0.13±0.03 ml/min/g KW) and reduced kidney injury scores. ICV leptin treatment also attenuated the reduction in circulating adiponectin levels that was observed in UIR-PF rats, and increased circulating white blood cells count compared to UIR-PF rats (16.3±1.3 vs. 9.8±0.6 k/mL). Therefore, we show that leptin, via its actions on the central nervous system, confers significant protection against major kidney dysfunction and injury in a model of ischemia/reperfusion-induced AKI.

Centrally administered growth hormone secretagogue receptor antagonist DLys decreases alcohol intake and preference in male mice.

Alcohol use disorder (AUD) is a highly prevalent public health problem. The ghrelin system has been identified as a potential target for therapeutic intervention for AUD. Previous work showed that systemic administration of the growth hormone secretagogue receptor (GHSR) antagonist DLys reduced alcohol intake and preference in male mice. Yet, it is unclear whether central or peripheral GHSRs mediated these effects. We hypothesized that alcohol consumption is driven by central GHSRs and addressed this hypothesis by testing the effects of central administration of DLys. Male C57BL/6J mice consumed alcohol in a two-bottle choice procedure (10% ethanol versus water). DLys (2 nmol) was administered intracerebroventricularly for 7 days to examine alcohol intake and preference. DLys decreased alcohol intake and preference but had no effect on food intake. The effects on alcohol intake and preference persisted after several administrations, indicating lack of tolerance to DLys' effects. These results suggest that central administration of DLys is sufficient to reduce alcohol drinking and that DLys remains effective after several administrations when given intracerebroventricularly. Moreover, this work suggests that the effects of intracerebroventricularly administered DLys are specific to alcohol and do not generalize to other calorie-driven behaviors.

Use of Technology in the Delivery of College Mental Health Services: Opportunities and Challenges

ABSTRACT This article will examine the seismic impact that technology currently has and is likely to increasingly have on college mental health services, both direct and indirect. Numerous resources and suggestions are offered to assist college counseling center administrators and clinical staff make decisions aligned with best clinical, ethical, regulatory, and legal practice. The field is changing in truly profound ways and the future is highly uncertain.

European Trends in Local Public Administration: Adapting to Globalization

The trend of globalization, accompanied by the dynamic development of social systems, places national states in a completely new position, in which institutions and administrative systems must be adapted. Any intervention in the field of public administration reform implies changes in major components, including central administration, local administration and public services. On the other hand, the development of democracy calls for the establishment of a new relationship between citizens and the administration, increasing and strengthening the role of local authorities and reconsidering the partnership with civil society. There are numerous reasons for the structural and functional modernization of the public administration in Romania, starting from the need for more efficient functioning of government institutions to the aspiration to become a member of the European Union. The present study aims to address these aspects, taking into account the impact of the reform measures at the public administration level that have been undertaken recently. Through the coherent and continuous development of the decentralization process in the next period, we will be able to witness the increase in the quality and efficiency of public services, and local administrations will respond to the demands of citizens and local development in an improved way. Keywords: development, Europe, municipalities, public administration

Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of OT-elicited reductions of body weight gain and adiposity in male diet-induced obese rats.

Recent studies indicate that central administration of oxytocin (OT) reduces body weight (BW) in high fat diet-induced obese (DIO) rodents by reducing energy intake and increasing energy expenditure (EE). Previous studies in our lab have shown that administration of OT into the fourth ventricle (4V; hindbrain) elicits weight loss and stimulates interscapular brown adipose tissue temperature (TIBAT) in DIO rats. We hypothesized that OT-elicited stimulation of sympathetic nervous system (SNS) activation of IBAT contributes to its ability to activate BAT and reduce BW in DIO rats. To test this, we determined the effect of disrupting SNS activation of IBAT on OT-elicited stimulation of TIBAT and reduction of BW in DIO rats. We first confirmed that bilateral surgical SNS denervation to IBAT was successful based on having achieved ≥ 60% reduction in IBAT norepinephrine (NE) content from DIO rats. NE content was selectively reduced in IBAT by 94.7 ± 2.7, 96.8 ± 1.8 and 85.9 ± 6.1% (P<0.05) at 1, 6 and 7-weeks post-denervation, respectively, and was unchanged in liver or inguinal white adipose tissue. We then measured the impact of bilateral surgical SNS denervation to IBAT on the ability of acute 4V OT (1, 5 μg) to stimulate TIBAT in DIO rats. We found that the high dose of 4V OT (5 μg) stimulated TIBAT similarly between sham and denervated rats (P=NS) and that the effects of 4V OT to stimulate TIBAT did not require beta-3 adrenergic receptor signaling. We subsequently measured the effect of bilateral surgical denervation of IBAT on the effect of chronic 4V OT (16 nmol/day) or vehicle infusion to reduce BW, adiposity and energy intake in DIO rats. Chronic 4V OT reduced BW gain by -7.2 ± 9.6 g and -14.1 ± 8.8 g in sham and denervated rats (P<0.05 vs vehicle treatment), respectively, and this effect was similar between groups (P=NS). These effects were associated with reductions in adiposity and energy intake (P<0.05). Collectively, these findings support the hypothesis that sympathetic innervation of IBAT is not required for central OT to increase BAT thermogenesis and reduce BW gain and adiposity in male DIO rats.

The Idea of ‘Loosening the Bond Between Ground and Structure’ in Antiquity and Archaeological Evidence on Antiseismic Foundations

Antiseismic structures in antiquity are often overlooked or disputed by those working in the field, even though they are not mentioned in written sources. At the very least, it should be recognized that some of the traditional structures and building techniques of ancient cultures in Anatolia and surrounding regions were antiseismic before today’s concrete structures. In fact, these techniques were sometimes applied over a wide geographical area and sometimes in a narrower region, as if under the control of a central government, administration or idea, and continue to be used for a long time. Archaeological studies reveal that some construction methods were widely used to support structures affected by dynamic loads. Such methods were applied and developed by engineers, architects and artisans who were fully aware of the effects of earthquakes on structures. Therefore, antiseismic structures must have emerged due to awareness of earthquake hazards. Wood in foundations and walls in Anatolia in the Bronze Ages, sand in Mesopotamia and Egypt, sand, ash, coal and lime in Greek architecture, and opus caementicum in Rome were applied in and under the foundation in more durable or long-lasting building construction techniques. Undoubtedly, wood and wood foundations have been known and used since the Bronze Age. Unfortunately, with the emergence of new materials and technologies, the traditional architectural understanding of Anatolia was almost wholly removed from construction practice. As in modern constructions, in archaeological studies, attention is paid to the structures’ above- ground units, while the underground foundation sections are overlooked. Data about the use of wood in the groundwork is sometimes discovered by chance. This article demonstrates that the idea of loosening the bond between structure and ground was known in ancient times. Although the technical solutions used in the past match the principles of base insulation, it is arguable whether they are genuinely antiseismic as they are today.