The Cenozoic alkaline basalts of northern and western Bohemia are part of the Central European Volcanic Province (CEVP) which extends from the Rhineland (Eifel, Germany) to Moravia (Czechoslovakia) and the Lover Silesia (Poland). Seven samlpes from locations within Czechoslovakia have been analyzed isotopically for the Rb-Sr and the Sm-Nd systems. Present-day, normalised 87Sr/86Sr ratios range from 0.7031 to 0.7036, and the corresponding 143Nd/144Nd ratios range from 0.51279 to 0.51286. An eigth sample from the Silurian basalts of the ‘St. Jan’ type (K-Ar age: 420 Ma) occuring in the Barrandian basin in Central Bohemia is also analysed. Its Present-day, normalised, 87Sr/86Sr ratio is 0.7031, and the corresponding 143Nd/144Nd ratio 0.51288.