IntroductionLarge-diameter femoral heads (≥36 mm) were introduced to decrease instability and improve the range of motion of the hip. We hypothesized regarding the clinical outcome and complications (dislocation, implant survivorship, and functional scores) following total hip replacement (THR) surgery in an Indian population who have smaller acetabulum compared to the western population.MethodologyA prospective study was conducted at a tertiary hospital from November 2011 to July 2013. A total of 70 patients with hip pathology were operated by a senior surgeon for THR using the anterolateral approach. The Harris Hip Scores were recorded pre and postoperatively in all patients. Postoperatively, radiographs were taken to check for evidence of implant loosening or osteolysis. The patients were followed up till a mean follow-up of 86.52 months (range: 74 to 108 months) in our cohort. Detailed clinical and radiographic results were available for 59 patients, while six died (three died of myocardial infarction (MI), two had cerebrovascular accident (CVA), and one patient died of pulmonary embolism) and five patients were lost to follow-up.ResultsOf the 59 hips, majority (76%) had acetabular inclination of 46-55 degrees. Ninety percent of the stems were in the central position and 10% were in the varus position. The average preoperative Harris Hip Score was 38.8 ± 5.7 (range: 24-46), which increased to 90.4 ± 7.3 (range: 78-94) at the last follow-up. A total of six patients died (four died of MI and two of CVA) and two patients had infection which was treated with antibiotics. Three cases of dislocation were observed; one following a fall one year after surgery and revision total hip arthroplasty was done and two cases while getting up from the bed which were managed with closed reduction and abduction brace for six weeks. Two cases of periprosthetic fracture were observed which were managed with plating.ConclusionLower dislocation rate and better range of movement reinforces the advantage of large-diameter femoral head during THR in the Indian population.