According to the literature, marginal gaps below 120μm are recommended for conventionally cemented crown restorations. Therefore, the null hypothesis tested was as follows: the upper bound of the 95% confidence interval of the marginal accuracy of chair-side generated lithium disilicate crowns lies below 120μm. Prior to definite insertion, the accuracy of 20 lithium disilicate crowns (e.max CAD LT) was evaluated by a replica technique. A light-body silicone was used to document the gap between crown and abutment. The thickness of the light-body silicone layer was examined under microscope (MM40, Nikon Corp., Tokyo, Japan; magnification, ×50) at four different landmarks (LM): LM1 = marginal discrepancy, LM2 = mid-axial discrepancy of the inner crown surface, LM3 = axio-occlusal discrepancy, and LM4 = mid-occlusal discrepancy. At LM1, the mean marginal discrepancy revealed 100μm (SD, ±61μm); the median was 81μm. The lower bound of the 95% confidence interval was 90μm, and the upper bound was 110μm. The means of internal gaps at LM2, LM3, and LM4 showed 148μm (SD, ±61μm), 227μm (SD, ±83μm), and 284μm (SD, ±95μm), respectively. The lower bounds of the 95% confidence interval revealed values between 137μm (LM2) and 269μm (LM4). The upper bounds were between 158μm (LM2) and 300μm (LM4). The null hypothesis was not rejected. Within the limits of the study, the chair-side generated lithium disilicate crowns exhibited a sufficient clinical accuracy.