ABSTRACT Coalbed methane, also known as coalbed methane gas, is a natural gas formed by the biogeochemical and pyrolysis processes during the formation and evolution of coal and stored in coal seams. Compared with conventional coalbed methane, deep coalbed methane has a rich resource and is an important substitute for natural gas increase, storage, and production. During the process of coalbed methane extraction, the inability of coal rock to bond well with cement slurry leads to a decrease in the quality of cementing, which has become one of the main problems affecting the extraction of deep coalbed methane. To address this issue, this paper first analyzes the microstructure of the coal rock-cement interface to reveal the mechanism of strengthening the coal rock-cement interface bonding. Then, using the wettability of coal rock as an evaluation index and the surfactant wetting modification method, the paper modified the surface of coal rock to enhance its hydrophilicity, optimized the suitable coal rock wetting modification agent, and finally evaluated the enhancement effect of the coal rock wetting modification agent on the quality of the coal rock-cement interface bonding through interface bonding experiments. The research results indicate that the hydrophobicity of coal rock surface is the main reason for the poor bonding between coal rock and cement. The three primary surfactants can improve the water wettability of coal and rock surfaces by 41.57%–52.95%, among which AES surfactant has the best improvement effect. After soaking in 0.5% AES solution at 85°C for 8 min, the hydrophilicity of coal rock can be increased by 72.3%. There are no obvious cracks between the coal rock-cement interface, and the bonding quality of the coal rock-cement interface has increased 2.69 times. Coal rock surface wetting modification can effectively enhance the interface bonding effect, which is conducive to improving the quality of cementing of deep coalbed methane.