Low duty-cycle (LDC) algorithm is interference mitigation technique, which can reduce the average interference to the existing radio systems by lowering pulse repetition interval or pulse occupation time. In this paper, the coexistence environment between low data rate ultra wideband (UWB) communication system such as wireless sensor network and the existing wideband system using orthogonal frequency division multiplexing (OFDM) such as 4th generation mobile cellular system (4G), worldwide interoperability for microwave access (WiMAX), and field pickup unit (FPU) is considered. In order to analyze the interference mitigation capability of LDC algorithm with impulse based UWB (LDC-UWB) system, the frame error rate (FER) of wideband OFDM system is examined for two types of LDC-UWB system: the signal with random polarity such as binary pole signals and without random polarity such as mono pole signals. We present that LDC algorithm is an efficient interference mitigation technique for low data rate UWB communication via computer simulations regardless of definitions of transmitted energy of UWB communication system, and also that the signal with random polarity is suitable for LDC-UWB system to mitigate interference to the other radio systems. We further investigate the adequate duty-cycle of LDC-UWB system for each definition of transmitted power of UWB communication.