Cell Dimensions Research Articles

Gaussian to flat-top beam shaping in an off-axis reflective scenario by a millimeter-wave metasurface.

In this paper, we present a metallic reflectarray for shaping the emitted Gaussian beam of a 100GHz horn antenna in reflective and off-axis mode. The proposed reflectarray is a compact planar surface consisting of a 2D array of unit cells with a thin Rogers 5880 substrate. This reflectarray offers advantages over other beam shapers in millimeter-wave (MMW) imaging, as it generates a flat-top beam in off-axis reflective mode and is straightforward to fabricate. To conduct a feasibility study, we first introduce the 1D reflectarray. The phase profile of the 1D reflectarray is a linear combination of a beam shaping phase profile based on geometrical optics (GO) and a compensating phase profile. The design of the 1D reflectarray involves tailoring the dimensions of the unit cells in one direction. We calculate the scattered field from the 1D reflectarray using the finite element method (FEM) and then determine the generated beam using the Fresnel diffraction integral. Subsequently, we design the 2D reflectarray following the same approach by using a 2D version of the proposed phase profile. The full-wave simulation is employed to calculate the generated beam at a certain distance from the reflectarray. The results reveal the successful generation of a high-quality flat-top beam, showcasing the proposed reflectarray as an evolutionary solution among beam shapers.

Rediscovery of Actinodontum lomaense: a range extension from Sierra Leone to southern Africa

The history of Actinodontum lomaense has been marked by taxonomic revisions since its initial discovery in samples from Sierra Leone during 1984. The reassignment from the genus Docidium to the genus Actinodontum primarily resulted from pronounced morphological differences, including variations in cell size and shape, ornamentations on the cell wall, and the presence of conical teeth-like structures at the isthmus. This article reports on the discovery of A. lomaense in two locations in southern Africa, marking a significant expansion of the geographical distribution range of the genus, from the tropical regions of Sierra Leone to sub-tropical environments in South Africa and the Kingdom of Lesotho. Additionally, the preference of Actinodontum species for relatively high altitudes, observed in this study, confirms a biogeographical pattern characterising this genus. Cell dimensions recorded in the southern African samples slightly exceeded dimensions previously reported in the literature. As a result, an extention of the dimension ranges for this species is proposed. Findings presented in this article, along with physico-chemical variables measured in their habitat, contribute to our understanding of the ecological preferences and distribution patterns of A. lomaense. It also provides valuable insights into the biogeography of desmid species on the African continent.

Reduced Pseudomonas aeruginosa Cell Size Observed on Planktonic Cultures Grown in the International Space Station.

Bacterial growth and behavior have been studied in microgravity in the past, but little focus has been directed to cell size despite its impact on a myriad of processes, including biofilm formation, which is impactful regarding crew health. To interrogate this characteristic, supernatant aliquots of P. aeruginosa cultured on different materials and media on board the International Space Station (ISS) as part of the Space Biofilms Project were analyzed. For that experiment, P. aeruginosa was grown in microgravity-with matching Earth controls-in modified artificial urine medium (mAUMg-high Pi) or LB Lennox supplemented with KNO3, and its formation of biofilms on six different materials was assessed. After one, two, and three days of incubation, the ISS crew terminated subsets of the experiment by fixation in paraformaldehyde, and aliquots of the supernatant were used for the planktonic cell size study presented here. The measurements were obtained post-flight through the use of phase contrast microscopy under oil immersion, a Moticam 10+ digital camera, and the FIJI image analysis program. Statistical comparisons were conducted to identify which treatments caused significant differences in cell dimensions using the Kruskal-Wallis and Dunn tests. There were statistically significant differences as a function of material present in the culture in both LBK and mAUMg-high Pi. Along with this, the data were also grouped by gravitational condition, media, and days of incubation. Comparison of planktonic cells cultured in microgravity showed reduced cell length (from 4% to 10% depending on the material) and diameter (from 1% to 10% depending on the material) with respect to their matching Earth controls, with the caveat that the cultures may have been at different points in their growth curve at a given time. In conclusion, smaller cells were observed on the cultures grown in microgravity, and cell size changed as a function of incubation time and the material upon which the culture grew. We describe these changes here and possible implications for human space travel in terms of crew health and potential applications.

Triple band frequency selective surface design for 5G mm‐wave communication with artificial neural networks

AbstractHigh‐performance frequency selective surfaces (FSSs) have gained attention for their spatial filtering characteristics in 5G communication systems. In this work, we propose an efficient and accurate design methodology for the FSS. Three different artificial neural network methods (ANN) are employed, and their performances are compared for analysis and synthesis purposes. Results show that GRNN has the highest performance for both training and test phase of ANN based FSS analysis and synthesis. A novel, compact, low‐profile triple band FSS unit cell is introduced, and the working mechanism is described. By applying ANN based design procedure, the unit cell dimensions to resonate at the 5G mm‐wave frequency band is extracted. A unit cell with the extracted physical dimensions is simulated with a full‐wave analysis tool. The simulation results show that the FSS has the filtering feature at the predetermined mm‐wave frequencies of the 5G communication. The prototype of the FSS is fabricated, as well. The simulations are verified experimentally with measurement results. The results show that proposed ANN based analysis and synthesis method can be an effective tool for the design of FSS band‐pass filter for 5G applications.

Design of a binary programmable transmitarray based on phase change material for beam steering applications in D-band

This paper introduces the design of a reconfigurable transmitarray operating within the D-band frequency range (110–170 GHz). The transmitarray unit cell is composed of three metal layers and two quartz dielectric substrates. It achieves a 1-bit phase shift resolution through the alternating states of two innovative switches integrated into the active transmitting patch of the unit cell. To address the challenge of miniaturization in the D-band, compact switches compatible with the proposed unit cell dimensions are introduced. These switches are constructed using phase change materials (PCM) that change between amorphous and crystalline states when exposed to heat. The paper includes a full-wave simulation of the unit cell, demonstrating an insertion loss below 1.5 dB across a wide frequency band of 27%. Additionally, a 10 ×\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$\ imes $$\\end{document} 10 elements transmitarray is synthesized using a numerical tool and its theoretical results are compared to full-wave electromagnetic simulations for validation purposes. The results indicate that by incorporating the proposed switches into the unit cell, the transmitarray achieves promising reconfiguration capabilities within the D-band. Moreover, the paper presents the architecture of a command line designed to bias the PCM switches. Notably, this command line represents a novel approach, as it enables individual biasing of each PCM switch using direct current (DC). The influence of these command lines on the transmitarray’s performance is thoroughly investigated. Although there is a compromise in the 1-dB gain bandwidth, the overall behavior of the transmitarray remains encouraging.

The Impact of 3D Nichoids and Matrix Stiffness on Primary Malignant Mesothelioma Cells.

Malignant mesothelioma is a type of cancer that affects the mesothelium. It is an aggressive and deadly form of cancer that is often caused by exposure to asbestos. At the molecular level, it is characterized by a low number of genetic mutations and high heterogeneity among patients. In this work, we analyzed the plasticity of gene expression of primary mesothelial cancer cells by comparing their properties on 2D versus 3D surfaces. First, we derived from primary human samples four independent primary cancer cells. Then, we used Nichoids, which are micro-engineered 3D substrates, as three-dimensional structures. Nichoids limit the dimension of adhering cells during expansion by counteracting cell migration between adjacent units of a substrate with their microarchitecture. Tumor cells grow effectively on Nichoids, where they show enhanced proliferation. We performed RNAseq analyses on all the samples and compared the gene expression pattern of Nichoid-grown tumor cells to that of cells grown in a 2D culture. The PCA analysis showed that 3D samples were more transcriptionally similar compared to the 2D ones. The 3D Nichoids induced a transcriptional remodeling that affected mainly genes involved in extracellular matrix assembly. Among these genes responsible for collagen formation, COL1A1 and COL5A1 exhibited elevated expression, suggesting changes in matrix stiffness. Overall, our data show that primary mesothelioma cells can be effectively expanded in Nichoids and that 3D growth affects the cells' tensegrity or the mechanical stability of their structure.

Near Net Shape Manufacturing of Sheets from Al-Cu-Li-Mg-Sc-Zr Alloy.

Thin twin-roll cast strips from a model Al-Cu-Mg-Li-Zr alloy with a small addition of Sc were prepared. A combination of a fast solidification rate and a favorable effect of Sc microalloying refines the grain size and the size of primary phase particles and reduces eutectic cell dimensions to 10-15 μm. Long-term homogenization annealings used in conventionally cast materials lasting several tens of hours followed by a necessary dimension reduction through rolling/extruding could be substituted by energy and material-saving procedure. It consists of two-step short annealings at 300 °C/30 min and 450 °C/30 min, followed by the refinement and hardening of the structure using constrained groove pressing. A dense dispersion of 10-20 nm spherical Al3(Sc,Zr) precipitates intensively forms during this treatment and effectively stabilizes the structure and inhibits the grain growth during subsequent solution treatment at 530 °C/30 min. Small (3%) pre-straining after quenching assures more uniform precipitation of strengthening Al2Cu (θ'), Al2CuMg (S'), and Al2CuLi (T1) particles during subsequent age-hardening annealing at 180 °C/14 h. The material does not contain a directional and anisotropic structure unavoidable in rolled or extruded sheets. The proposed procedure thus represents a model near net shape processing strategy for manufacturing lightweight high-strength sheets for cryogenic applications in aeronautics.

Tight coupling of cell width to nucleoid structure in Escherichia coli

Cell dimensions of rod-shaped bacteria such as Escherichia coli are connected to mass growth and chromosome replication. During their interdivision cycle (τ min), cells enlarge by elongation only, but at faster growth in richer media, they are also wider. Changes in width W upon nutritional shift-up (shortening τ) occur during the division process. The elusive signal directing the mechanism for W determination is likely related to the tightly linked duplications of the nucleoid (DNA) and the sacculus (peptidoglycan), the only two structures (macromolecules) existing in a single copy that are coupled, temporally and spatially. Six known parameters related to the nucleoid structure and replication are reasonable candidates to convey such a signal, all simple functions of the key number of replication positions n(=C/τ), the ratio between the rates of growth (τ−1) and of replication (C−1). The current analysis of available literature-recorded data discovered that, of these, nucleoid complexity NC[=(2n−1)/(n×ln2)] is by far the most likely parameter affecting cell width W. The exceedingly high correlations found between these two seemingly unrelated measures (NC and W) indicate that coupling between them is of major importance to the species’ survival. As an exciting corollary, to the best of our knowledge, a new, indirect approach to estimate DNA replication rate is revealed. Potential involvement of DNA topoisomerases in W determination is also proposed and discussed.

A Quad-Band Highly Selective Frequency Selective Surface with Ultra-Wideband Rejection.

In this paper, a highly selective quad-band frequency selective surface (FSS) with ultra-wideband rejection is presented. The proposed FSS structure was developed by cascading five metallic layers by three thin dielectric substrates. The five metallic layers are composed of two bent slot layers, two metallic square rings, and a metal patch. The dimensions of the unit cell are 0.13λ0× 0.13λ0× 0.18λ0 (λ0 is the free-space wavelength at the first operating frequency). The proposed structure achieves four transmission bands and has two wide stop-bands located at 1 to 5.5 GHz and 14 to 40 GHz, with a suppressed transmission coefficient below -20 dB. In order to verify the simulation results, an FSS prototype was fabricated and measured. It can be observed that the measured results are in favorable agreement with the simulation results. Its multiple narrow passbands and highly selective and ultra-wideband rejection properties ensure that our design can play a significant role in narrowband antennas, spatial filters, and many other fields.

Symmetrically structured epsilon negative metamaterial for antenna gain enhancement

An epsilon negative metamaterial (MTM) is presented in this article that bears a symmetrical structure and shows a transmission coefficient (S21) resonance at 2.78 GHz. The proposed MTM unit cell comprises an outer square ring with horizontally oriented splits, connected along the vertical axis to a circular inner ring featuring vertically oriented splits, forming an interconnected structure. The electrical dimension of the MTM cell is 0.08λ × 0.084λ, and here wavelength, λ is determined at 2.4 GHz. The MTM shows negative permittivity, near zero permeability as well as refractive index. The electric field, Magnetic field, and current distribution have been analyzed to realize resonance behavior. The compactness of the MTM is identified through an effective medium ratio (EMR) of 12.2. Moreover, an equivalent circuit is modeled and Advanced Design Systems (ADS) is utilized to confirm its performance. The prototype of the metamaterial is developed and a measured result is taken that exhibits a well-matching with the simulation result. Application of this metamaterial is checked through designing and developing an antenna and MTM is used as a superstrate over the antenna. Both the simulation and measured results reveal that as a superstrate, MTM helps to increase the antenna gain by more than 100% with less effect on the bandwidth. Thus, this new metamaterial can be a good candidate as an antenna element for increasing performance. Moreover, the proposed antenna-MTM system can be utilized for wireless power transmission as it provides an adequate gain in a compact 3D structure.

Swastika-shaped rotationally symmetric quadruple-structured near-infrared metamaterial absorber for absorbing solar energy

In this work, silicon dioxide based four-fold swastika shaped metamaterial nano structure absorber for solar radiation absorption in the near infrared (NIR) regime is proposed. The dimension of the unit cell is 648.50 × 648.50 nm2 which is designed on dielectric silicon dioxide and metallic conductor aluminum. The proposed structure is investigated by the finite-deference time domain (FDTD) method based software CST microwave studio. The metamaterial absorber (MMA) unit cell is simulated within the frequency range (200–398) THz that yielded dual resonance peaks at 260 THz and 378.0 THz with 95.50 % and 97.32 % of absorbance of solar energy, respectively. Additionally, the proposed nano design structure of unit cell was boosted up to attain the dual absorption band by engineering the design parameters. The electromagnetic response of the MMA was theoretically inspected and the excellent properties of the proposed designed absorber have promising applications in plasma-enhanced photovoltaic, optical absorption switching and infrared modulator optical communication.

Rheological investigations on frequency selective surface carbon composite microwave absorber.

A high-performance stealth platform is one of the crucial requirements in defence technology that could practically be realized by building effective microwave frequency selective surface (FSS) absorbers. Herein, we report the design and manufacturing of an absorber by tuning the rheology of cell architecture. Initially, a fan-shaped cell (10.4 mm2) was designed for its surface and bulk rheology. The FSS overlayer composition was investigated using SEM, EDX, and XRD and tuned for 0.25% carbon: 1.5% silver to achieve the ink resistivity ∼255 Ω □-1. The bulk rheology was optimized for air (Roha) spacer (thickness ∼2.8 mm), interlayer dielectrics (0.2 mm each), carbon composition (5%), and cell dimension (10.2 mm). Analyses are presented for absorption loss (RC, dB), bandwidth (GHz), resonance dispersion, and constitutive (ε, μ) parameters, compounded with an equivalent circuit model with the settings R = 273.55 Ω, L = 2.25 nH, C = 0.057 pF and the Fabry-Perot reactance mode@10 GHz. The bi-modal response was investigated for induced polarization, electromagnetic fields, volume power distribution, and angular (Θ = 0°-50°) and rotational stability (Φ = 0°-90°) against TE/TM incidences. The FSS pattern was implemented using a screen printing technique to fabricate a prototype absorber and subjected to the free space measurements in an anechoic chamber. The prototype behaviour was found to be commensurate with the simulated performance, thereby achieving a figure of merit of RC ∼-25 dB@10 GHz, accessible bandwidth 4 GHz (in X band) by using the thickness of 0.057 λ0. Details are presented in this study.

Evaluation of a membrane filter and platelet-rich plasma (PRP) product obtained from a prototype PRP kit that works through a new method for separating PRP based on cell dimensions

The harvesting of platelet-rich plasma (PRP) from whole blood based on cell density is a standard procedure that is currently applied to commercially available PRP kits. Leukocytes and erythrocytes, which are closer in density, contaminate a significant amount of PRP products, mostly commercial PRP kits. In this study, we tested membrane filters and PRP products from our prototype PRP kit. We did this by putting a membrane filter with pores of 2 μm in the middle of the tube, which is a new way to separate things based on the cell dimension method (CDM). The evaluations were performed for membrane filter use, hematology analysis, blood smears, viability and cytotoxicity assays, and fibrin structure by scanning electron microscopy (SEM). Compared to the density method (DM), the CDM enables the elimination of a significant number of leukocytes and erythrocytes from the PRPs (CDM-PRP) and a significant increase in the number of platelets compared to the whole blood and DM-PRP. Furthermore, both DM-PRP and CDM-PRP increased the cell viability in L929 cells by adding them at 5% in the culture medium. In addition to CDM-PRP having the lowest cytotoxicity based on the LDH assay, the fibrin structure of CDM-PRP blood clots is characterized by thickness and firmness with a network structure. Thus, we believe that the PRP from the prototype PRP kit meets the requirements as a biomaterial for medical treatments.

Синтез хромового соединения методом CVD и его исследование физическими методами

The article presents the results of research on the synthesis of a chromium-containing compound based on the chromium salt of natural petroleum acids isolated from raw oil by leaching. The synthesis was carried out by the CVD method under conditions of supplying Ar and H2 in a ratio of 2:1, for 4-8 hours, at a temperature of 400-800oC. As a result of CVD (Chemical vapor deposition) operations, a crystalline rhombohedral structure of chromium oxide (Cr(III)Cat) was formed from the five- and hexagonal structure of salts of natural petroleum acids, confirmed by X-ray analysis. As a result of the X-ray analysis of the Cr(III)Cat sample, the cell dimensions were determined to be а = b = 4.958 Å, c = 13.593 Å, α = β = 90°, γ = 120°. The article presents the hypothetical structure of a synthesized Cr(III)Cat sample consisting of chromium oxide (nCr2O3). The work also presents the results of thermal TG/DTG/DTA analysis of the chromic salt of natural petroleum acids, where the decomposition of the sample from a temperature of 189.30C to 264.90C is observed. The distribution of particles of a synthesized Cr(III)Cat sample formed in the range of 800-2000 nm, the hydrodynamic radii of 1482.3 nm, was studied using the dynamic light scattering (DLS) method.

Fe-modified NASICON-type Na3V2(PO4)3 as a cathode material for sodium ion batteries.

The sol-gel method is used to synthesize a new compound called Na3Fe0.8V1.2(PO4)3/C (NFVP/C), which has a crystal structure and belongs to the NASICON-type family. The dimensions of NFVP's unit cell are a = 8.717 (1) Å, c = 21.84 (1) Å, and V = 1437.27 (0) Å3. The Na‖NFVP/C battery provides a discharge potential of 3.43 V compared to Na+/Na, an intriguing rate capability of 76.2 mA h g-1 at 40C, and maintains an impressive capacity of 97.8% after 500 cycles at 5C. The excellent efficiency of Na3Fe0.8V1.2(PO4)3/C can be ascribed to its elevated Na+ conductivity and reduced energy barrier for sodium-ion diffusion. The NASICON-type Na3Fe0.8V1.2(PO4)3/C is a promising material for sodium-ion batteries.

DUAL-BAND BANDSTOP FILTERS BASED ON ULTRA THIN FREQUENCY SELECTIVE SURFACES

In this paper, we present designs for terahertz filters with two independent stopbands based on periodic metallic resonant structures patterned on the dielectric substrate. Two simple and thin structures are proposed to realize required characteristics for single-polarized and dual polarized filter designs. To realize single polarized one, a unit cell of the proposed periodic structure consists of two sets rectangular shape conducting metal patches patterned on the top of the dielectric substrate, and the dual-band response is due the lattice resonances observed in the unit cell. To realize dual polarized filter design, a modified unit cell is considered with additional patches on the bottom of the dielectric substrate. The patches on the bottom layer are the same ones as on the top layer but orthogonally oriented. For this case, polarization-independent frequency response can be obtained after geometric optimization of the unit cell because the top and the bottom layers resonantly interact with only the TE or TM incident plane wave to minimize cross coupling effects between the layers. In order to intensively understand the transmission performance of the proposed filters, a large number of simulations using integral equation method are performed based on the different values for permittivity, period of the unit cell, dielectric thickness, and geometric dimensions. The electric field distributions are analyzed to understand the mechanism of the resonance behavior.

Ba15Zr14Te42: a new complex ternary telluride structure with low thermal conductivity.

Heavier metal-based tellurides with complex structures are of great interest for thermoelectric (TE) applications. Herein, we report the synthesis of a new telluride Ba15Zr14Te42 using high-temperature reactions of elements. Our single-crystal X-ray diffraction study reveals that it crystallizes in the space group R3̄c of the trigonal crystal system and is isostructural to its Se analogue Ba15Zr14Se42 complex. The unit cell of the structure accommodates 426 atoms with cell dimensions of a = b = 13.2666(10) Å, c = 96.195(9) Å, and V = 14 662(3) Å3. This structure consists of 18 unique crystallographic atoms (3 × Ba, 8 × Zr, and 7 × Te). The bonding of Zr and Te atoms creates chains of ∞1[Zr14Te42]30-, which are separated by the Ba2+ cations. Although all the Zr atoms have a coordination number of 6, they form two types of coordination polyhedra by bonding with six Te atoms: slightly distorted octahedral and trigonal prisms of ZrTe6. We have synthesized polycrystalline Ba15Zr14Q42 (Q = Se/Te) samples, which were characterized by optical absorption studies to reveal direct bandgaps of <0.5 eV for the Te analogue and 1.3(1) eV for the Se analogue. The lattice thermal conductivity (klat) values of the samples are ultralow: ∼0.46 W mK-1 and ∼0.30 W mK-1 at 773 K for the Te and Se analogues, respectively. Temperature-dependent resistivity and thermopower studies were carried out for the Ba15Zr14Te42, which showed the p-type degenerate semiconducting nature of the sample at high temperatures. The theoretical DFT studies predict a bandgap of 0.14 eV for the Ba15Zr14Te42 phase.

The N-terminal domain of Type IV-A1 CRISPR-associated DinG is vulnerable to proteolysis.

CasDinG is an ATP-dependent 5'-3' DNA helicase essential for bacterial Type IV-A1 CRISPR associated immunity. CasDinG contains an essential N-terminal domain predicted to bind DNA. To better understand the role of the N-terminal domain, we attempted to co-crystallize CasDinG with DNA substrates. We successfully crystallized CasDinG in a tightly packed, crystal conformation with previously unobserved unit cell dimensions. However, the structure lacked electron density for a bound DNA substrate and the CasDinG N-terminal domain. Additionally, the tight crystal packing disallowed space for the N-terminal domain, indicating that the N-terminal domain was proteolyzed before crystallization. Follow up experiments revealed that the N-terminal domain of CasDinG is proteolyzed after a few days at room temperature, but is protected from proteolysis at 4°C. These data provide a distinct x-ray crystal structure of CasDinG and indicate the essential N-terminal domain of CasDinG is prone to proteolysis.

Impacts of heavy metal and nutrient accumulation on the vegetative, anatomical and reproductive characteristics and phytoremediation efficiency of Azolla Filiculoides L .

abstract: Aquatic ecosystems are susceptible to contamination from various sources, including agricultural wastewater, urban sewage and industrial activities. This study investigated the phytoremediation potential of the aquatic fern Azolla filiculoides L. in removing heavy metals and nutrients from the Anzali lagoon, in the Caspian Sea. Water and plant samples were collected from diverse areas within the lagoon. The bioconcentration factor for potassium and lead surpassed one, indicating significant root absorption. Conversely, for manganese and zinc, the values were below one, suggesting restricted absorption by the roots. However, the biotranslocation factor exceeded one for all elements, with phosphorus and zinc exhibiting the highest values. This indicates that the plants effectively transferred heavy metals and nutrients to the shoots. A. filiculoides growing in contaminated areas had smaller epidermal cell dimensions, a thicker stem cortex, and thicker tracheid and sieve cells in the roots compared to those in uncontaminated areas. In contaminated areas, mature sporangium capsules opened rapidly, accelerating the maturation and germination of spores, thereby enhancing the survival capacity of A. filiculoides . The study demonstrates Azolla filiculoides 's effectiveness as a phytoremediator in the Anzali lagoon, highlighting its potential for sustainable and eco-friendly bioremediation of heavy metal-contaminated areas through ongoing research and technological progress.

ЭФФЕКТИВНОСТЬ ПРИМЕНЕНИЯ КРИВОШИПНО-ПОЛЗУННОГО ПРИВОДА ДЛЯ ФРЕЗЕРОВАНИЯ ВАФЕЛЬНОГО ФОНА

The paper presents the design of an experimental cutting tool feed drive based on a slider-crank mechanism. A feature of the technology of milling a regular waffle background pattern is the need for regular repetition of cells, usually rectangular shape. This requires the development of a tool feed mechanism that provides а high processing speed and a significant reduction in cutting forces to prevent deformation of the cell shape. The drive design presented in the work provides feed rate up to 43 m/min with cutting speed up to 942 m/min. This eliminates the exit of the mechanism out of the cell dimensions, as well as provides a significant reduction of cutting forces up to 10 N and removes the problem of using coolant (dry machining). This is a feature of the high-speed milling mode, when the feed rate and cutting speed are significantly higher than traditional ones, and the cutting depth does not exceed 1 mm. The productivity of this milling process is much higher than traditional milling modes and, in addition, it causes less heating of the part, as almost all the heat escapes with the chips. The practical significance of the development is the increase of productivity of the equipment for waffle background milling in fuel tanks from aluminium alloys due to the application of the high-speed drive based on the slider-crank mechanism. The authors offered to mount it instead of the standard spindle on large-sized milling gantry-type machines. This makes it possible to use the high-speed milling modes at cutting forces of several newtons for reducing the weight of the power and moving parts of the drive and increasing the feed rate.