Versatile polyphenolic platforms in regulating cell biology. Abstract Polyphenolic materials are a class of fascinating and versatile bioinspired materials for biointerfacial engineering. In particular, due to the presence of active chemical groups, ... Read More
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Versatile polyphenolic platforms in regulating cell biology.
- Chemical Society reviews
on May 10, 2022
DNA Nanotechnology-Based Supramolecular Assemblies for Targeted Biomedical Applications.
- Chemical record (New York, N.Y.)
on May 9, 2022
DNA Nanotechnology-Based Supramolecular Assemblies for Targeted Biomedical Applications. Abstract DNA is a polyanionic, hydrophilic, and natural biopolymer that offers properties such as biodegradability, biocompatibility, non-toxicity, and non-immun... Read More
The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function.
- Oncogene
on May 9, 2022
The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function. Abstract It is known that Rho GTPases control different aspects of the biology of skin stem cells (SSCs). However, little information is available on t... Read More
Super-Resolution Microscopy for Structural Cell Biology.
- Annual review of biophysics
- VOL. 51
on May 9, 2022
Abstract Super-resolution microscopy techniques, and specifically single-molecule localization microscopy (SMLM), are approaching nanometer resolution inside cells and thus have great potential to complement structural biology techniques such as elec... Read More
CXCR5/CXCL13 pathway, a key driver for migration of regulatory B10 cells, is defective in patients with rheumatoid arthritis.
- Rheumatology (Oxford, England)
- VOL. 61
on May 5, 2022
CXCR5/CXCL13 pathway, a key driver for migration of regulatory B10 cells, is defective in patients with rheumatoid arthritis. Abstract Chemokines (CKs) are key players of immune-cell homing and differentiation. CK receptors (CKRs) can be used to defi... Read More
Commonly Used Alkylating Agents Limit Persulfide Detection by Converting Protein Persulfides into Thioethers.
- Angewandte Chemie (International ed. in English)
on May 4, 2022
Commonly Used Alkylating Agents Limit Persulfide Detection by Converting Protein Persulfides into Thioethers. Abstract Protein persulfides (R-S-SH) have emerged as a common post-translational modification. Detection and quantitation of protein persul... Read More
The primate malaria parasites Plasmodium malariae, Plasmodium brasilianum and Plasmodium ovale spp.: genomic insights into distribution, dispersal and host transitions.
- Malaria journal
- VOL. 21
on May 3, 2022
Abstract During the twentieth century, there was an explosion in understanding of the malaria parasites infecting humans and wild primates. This was built on three main data sources: from detailed descriptive morphology, from observational histories ... Read More
Treating intrauterine adhesion using conditionally reprogrammed physiological endometrial epithelial cells.
- Stem cell research & therapy
- VOL. 13
on May 3, 2022
Treating intrauterine adhesion using conditionally reprogrammed physiological endometrial epithelial cells. Abstract There is unmet need for effective therapies of intrauterine adhesions (IUAs) that are common cause of menstrual disturbance and infer... Read More
Canine mast cell tumours part I: Clinical and survival outcomes.
- Veterinary medicine and science
on May 3, 2022
Canine mast cell tumours part I: Clinical and survival outcomes. Abstract Dogs have a species-specific susceptibility for developing mast cell tumours (MCTs). Mutations in the KIT proto-oncogene (KIT) are known to contribute to the neoplastic biology... Read More
Exploring the Role of Ubiquitin-Proteasome System in Parkinson's Disease.
- Molecular neurobiology
on May 3, 2022
Exploring the Role of Ubiquitin-Proteasome System in Parkinson 's Disease. Abstract Over the last decade, researchers have discovered that a group of apparently unrelated neurodegenerative disorders, such as Parkinson 's disease, have remarkable cell... Read More
Cell membrane fluidity and ROS resistance define DMSO tolerance of cryopreserved synovial MSCs and HUVECs.
- Stem cell research & therapy
- VOL. 13
on May 3, 2022
Abstract Synovial mesenchymal stem cells (MSCs) have high freeze-thaw tolerance, whereas human umbilical vein endothelial cells (HUVECs) have low freezing tolerance. The differences in cell type-specific freeze-thaw tolerance and the mechanisms invol... Read More
Labile iron accumulation augments T follicular helper cell differentiation.
- The Journal of clinical investigation
- VOL. 132
on May 2, 2022
Labile iron accumulation augments T follicular helper cell differentiation. Abstract T follicular helper (Tfh) cells are a subset of CD4 + T cells that are essential in the pathogenesis of systemic lupus erythematosus (SLE). Notably, iron is required... Read More
Bioprosthetic Aortic Valve Degeneration: a Review from a Basic Science Perspective.
- Brazilian journal of cardiovascular surgery
- VOL. 37
on May 2, 2022
Bioprosthetic Aortic Valve Degeneration: a Review from a Basic Science Perspective. Abstract The increase in the prevalence of aortic stenosis due to an aging population has led to an increasing number of surgical aortic valve replacements. Over the ... Read More
The CD3ζ adaptor structure determines functional differences between human and mouse CD16 Fc receptor signaling.
- The Journal of experimental medicine
- VOL. 219
on May 2, 2022
The CD3ζ adaptor structure determines functional differences between human and mouse CD16 Fc receptor signaling. Abstract Natural killer (NK) cells can detect antibody-coated cells through recognition by the CD16 Fc receptor. The importance of CD16 i... Read More
Lipid metabolism in T cell signaling and function.
- Nature chemical biology
- VOL. 18
on May 1, 2022
Lipid metabolism in T cell signaling and function. Abstract T cells orchestrate adaptive immunity against pathogens and other immune challenges, but their dysfunction can also mediate the pathogenesis of cancer and autoimmunity. Metabolic adaptation ... Read More
An update on genetically encoded lipid biosensors
- Molecular biology of the cell
- VOL. 33
on May 1, 2022
Abstract Specific lipid species play central roles in cell biology. Their presence or enrichment in individual membranes can control properties or direct protein localization and/or activity. Therefore, probes to detect and observe these lipids in in... Read More
An update on genetically encoded lipid biosensors
- Molecular Biology of the Cell
- VOL. 33
on May 1, 2022
Abstract Specific lipid species play central roles in cell biology. Their presence or enrichment in individual membranes can control properties or direct protein localization and/or activity. Therefore, probes to detect and observe these lipids in in... Read More
From genes to modules, from cells to ecosystems.
- Molecular systems biology
- VOL. 18
on May 1, 2022
From genes to modules, from cells to ecosystems. Abstract Twenty years ago, molecular biology transitioned from predominantly studying genes as isolated elements to viewing them as part of complex modules, giving rise to the field of systems biology.... Read More
Mechanisms of pulmonary vascular dysfunction in pulmonary hypertension and implications for novel therapies.
- American journal of physiology. Heart and circulatory physiology
- VOL. 322
on May 1, 2022
Mechanisms of pulmonary vascular dysfunction in pulmonary hypertension and implications for novel therapies. Abstract Pulmonary hypertension (PH) is a serious disease characterized by various degrees of pulmonary vasoconstriction and progressive fibr... Read More
Preprint Highlight: FLAgellum Member 8 modulates extravascular trypanosome distribution in the mammalian host
- Molecular biology of the cell
- VOL. 33
on May 1, 2022
Preprint Highlight: FLAgellum Member 8 modulates extravascular trypanosome distribution in the mammalian host Abstract Trypanosomes are extracellular protozoan parasites that cause human and animal disease. Trypanosomes predominantly inhabit the bloo... Read More