Flow cytometry (FCM) is a widely used technique to simultaneously measure various characteristics of a cell or particle. Most of reliable software for FCM data analysis are commercially available at high costs. A few R packages are available; however... Read More
Cell Biology Research Articles
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BCyto: A shiny app for flow cytometry data analysis.
- Molecular and cellular probes
- VOL. 65
on Oct 1, 2022
BCyto: A shiny app for flow cytometry data analysis
- Molecular and Cellular Probes
- VOL. 65
on Oct 1, 2022
Flow cytometry (FCM) is a widely used technique to simultaneously measure various characteristics of a cell or particle. Most of reliable software for FCM data analysis are commercially available at high costs. A few R packages are available; however... Read More
Recent progress in dissecting ubiquitin signals with chemical biology tools
- Current Opinion in Chemical Biology
- VOL. 70
on Oct 1, 2022
Protein ubiquitination regulates almost all eukaryotic cellular processes, and is of very high complexity due to the diversity of ubiquitin (Ub) modifications including mono-, multiply mono-, homotypic poly-, and even heterotypic poly-ubiquitination.... Read More
Flow cytometry for B-cell subset analysis in immunodeficiencies
- Journal of Immunological Methods
- VOL. 509
on Oct 1, 2022
B cells are one of the fundamental components of the adaptive immune system and are best known for their ability to produce antibodies. Among the various types of inborn errors of immunity, antibody deficiencies represent the largest group in terms o... Read More
Anatomical journals as publication platforms for dental research
- Annals of Anatomy - Anatomischer Anzeiger
- VOL. 244
on Oct 1, 2022
For the benefit of medical and dental patients, there is a great need for international knowledge exchange, intensive cooperation between basic science and clinical experience and the integration of new research results into everyday practice. Equall... Read More
Surface micropatterning for the formation of an in vitro functional endothelial model for cell-based biosensors
- Biosensors and Bioelectronics
- VOL. 214
on Oct 1, 2022
Label-free biosensing, such as with surface plasmon resonance (SPR), is a highly efficient method for monitoring the responses of living cells exposed to pharmacological agents and biochemical stimuli in vitro. Conventional cell culture protocols use... Read More
Automated quantification of dopaminergic immunostained neurons in substantia nigra using freely available software.
- Medical & biological engineering & computing
- VOL. 60
on Oct 1, 2022
Computerized techniques for image analysis are critical for progress in cell biology. The complexity of the data in current methods eliminates the need for manual image analysis and usually requires the application of multiple algorithms sequentially... Read More
Preprint Highlight: Dynamic interplay of protrusive microtubule and contractile actomyosin forces drive tissue extension
- Molecular Biology of the Cell
- VOL. 33
on Oct 1, 2022
Cytoskeletal mechanical forces shape tissues during development. Although the role of the actomyosin machinery is extensively studied, how microtubules actively generate forces to shape tissues remains unknown. Combining in vivo experiments and simu... Read More
Integrated analysis of the tumor microenvironment using a reconfigurable microfluidic cell culture platform.
- FASEB journal : official publication of the Federation of American Societies for Experimental Biology
- VOL. 36
on Oct 1, 2022
The tumor microenvironment (TME) is a complex network of non-malignant cells and stroma that perform a wide array of vital roles in tumor growth, immune evasion, metastasis, and therapeutic resistance. These highly diverse roles have been shown to be... Read More
How many authors does it take to publish a high profile or classic paper?
- Molecular Biology of the Cell
- VOL. 33
on Oct 1, 2022
Although the process of publishing a scientific paper has gotten simpler, it is increasingly difficult to publish a paper in high profile journals. We have analyzed the publishing data in the cell biology field and found several alarming trends deve... Read More
Stem cell therapy for central nervous system disorders: Metabolic interactions between transplanted cells and local microenvironments
- Neurobiology of Disease
- VOL. 173
on Oct 1, 2022
Stem cell therapy is a promising and rapidly advancing treatment strategy for a multitude of neurologic disorders. Yet, while early phase clinical trials are being pursued in many disorders, the mechanism of action often remains unclear. One importan... Read More
Mitochondrial quality control in health and in Parkinson’s disease
- Physiological Reviews
- VOL. 102
on Oct 1, 2022
As a central hub for cellular metabolism and intracellular signaling, the mitochondrion is a pivotal organelle, dysfunction of which has been linked to several human diseases including neurodegenerative disorders and in particular Parkinson’s diseas... Read More
Aryl hydrocarbon receptor (AhR)-mediated signaling as a critical regulator of skeletal cell biology
- Journal of Molecular Endocrinology
- VOL. 69
on Oct 1, 2022
The aryl hydrocarbon receptor (AhR) has been implicated in regulating skeletal progenitor cells and the activity of bone-forming osteoblasts and bone-resorbing osteoclasts, thereby impacting bone mass and the risk of skeletal fractures. The AhR also ... Read More
Spotlight on plant RNA-containing extracellular vesicles
- Current Opinion in Plant Biology
- VOL. 69
on Oct 1, 2022
Extracellular vesicles (EVs) carrying RNA have attracted growing attention in plant cell biology. For a long time, EV release or uptake through the rigid plant cell wall was considered to be impossible and RNA outside cells to be unstable. Identified... Read More
Functional prominence of natural killer cells and natural killer T cells in pregnancy and infertility: A comprehensive review and update
- Pathology - Research and Practice
- VOL. 238
on Oct 1, 2022
During pregnancy, complicated connections are formed between a mother and a fetus. In a successful pregnancy, the maternal-fetal interface is affected by dynamic changes, and the fetus is protected against the mother's immune system. Natural killer (... Read More
CT-167 Using the Sodium Iodide Symporter to Visualize CAR-T Cell Trafficking
- Clinical Lymphoma Myeloma and Leukemia
- VOL. 22
on Oct 1, 2022
Chimeric antigen receptor T (CAR-T) cell therapy revolutionized the treatment of refractory B cell malignancies, but relapses occur through a variety of incompletely understood mechanisms. Currently, tracking CAR-T expansion and persistence in patien... Read More
Amide Proton Transfer–weighted MRI: Insight into Cancer Cell Biology
- Radiology
- VOL. 305
on Oct 1, 2022
Improved Methods for Bulk Cultivation and Fixation of Loxodes Ciliates for Fluorescence Microscopy
- Protist
- VOL. 173
on Oct 1, 2022
Loxodes is one of the best ecologically characterized ciliate genera with numerous intriguing physiological abilities, including gravity-sensing organelles and nitrate respiration. However, these cells have been considered challenging to cultivate in... Read More
Splanchnic vein thrombosis associated with myeloproliferative neoplasms
- Thrombosis Research
- VOL. 218
on Oct 1, 2022
Splanchnic vein thrombosis (SVT) in the setting of myeloproliferative neoplasm (MPN) is a unique clinical entity that requires close interdisciplinary coordination for proper diagnosis and management. The pathobiology of MPN-SVT is not fully understo... Read More
Exogenously Scavenged and Endogenously Synthesized Heme Are Differentially Utilized by Mycobacterium tuberculosis.
- Microbiology spectrum
on Sep 28, 2022
Heme is both an essential cofactor and an abundant source of nutritional iron for the human pathogen Mycobacterium tuberculosis. While heme is required for M. tuberculosis survival and virulence, it is also potentially cytotoxic. Since M. tuberculosi... Read More