CECT Scan Research Articles

Para aortic ganglioneuroma presenting as Cushing's syndrome

We present a case of an eight-year-old female presenting with four months history of progressive weight gain, short stature, obesity, mild acanthosis, moon facies and buffalo hump. Biochemically, low-dose and high-dose Dexamethasone tests were not suppressible, ACTH was raised and 24h urinary metanephrines were normal. The CECT scan showed a 3cm paraganglioma. Tumor was excised via 11th rib transcostal approach and the mass was found arising from the sympathetic chain. Histopathology was suggestive of ganglioneuroma positive for ACTH immunostaining.

An Unexpected Cause Of Spontaneous Perinephric Urinoma: A Case Report

An Unexpected Cause Of Spontaneous Perinephric Urinoma: A Case Report

A randomized phase II trial of neoadjuvant chemotherapy for patients with resectable pancreatic cancer: Gemcitabine alone vs. gemcitabine combined with cisplatin

4215 Background: Overall 5 year survival for patients with pancreatic cancer is <1%, but with resectable disease ranges from 11%–24%. In units with an aggressive policy of surgical exploration, resection rates are only 50–60%. The greatest impact on survival will be achieved by increasing the resection rate. Preoperative chemotherapy may improve operability and therefore survival. Methods: 50 patients were randomized between 2 regimens of neoadjuvant therapy. 24 patients were randomized to gemcitabine (1000mg/m2) (G) every 7 days for 43 days. 26 patients were randomized to gemcitabine (1000mg/m2) and cisplatin (25mg/m2) (GC) every 7 days: 7 patients received an original schedule omitting day 22; due to neutropenia, the subsequent 19 patients received a revised schedule of GC omitting days 15 and 36. All patients had radiological and clinical evidence of pancreatic cancer considered resectable on CE-CT scan and were suitable for surgical exploration. Results: 22/24 G patients underwent treatment receiving ...

Neuroblastoma with divergent immunophenotype - an FNAB based case report with review of literature

A case of neuroblastoma with divergent vimentin and cytokeratin positivity in an 11 year old boy is presented. The initial radiological impression was of a left renal mass consistent with Wilms' tumor. FNA revealed a tumor with an essentially discrete population of small round cells, and a few rosette-like structures. However, the presence of rare epithelial looking cells and stromal fragments coupled with vimentin and cytokeratin positivity prompted a diagnosis of a malignant round cell tumor consistent with Wilm's tumor. The appearance of skull metastasis a few weeks later prompted a review of the diagnosis. A repeat CECT scan clearly indicated a left adrenal origin of the mass. Material from a repeat FNA was submitted for electron microscopy. The detection of neurites confirmed a neuroblastoma. The earlier vimentin and cytokeratin positivity, confirmed by flowcytometry, was taken as evidence of a divergent immunophenotype. The subject of divergent differentiation in small round-cell tumors with neural features is reviewed.

脳室内出血で発症した脈絡叢血管腫の4手術例

In this paper, the authors reported four cases of choroid plexus angioma which were detected by computerized tomography and were excised surgically. These four cases had the following characteristic CT findings. The initial CT scan showed intraventricular hemorrhage with or without intracerebral hematoma in each case. More than two weeks later, when the intraventricular hemorrhage had disappeared completely on the plain CT scan, a small high density area corresponding to the site of the angioma was demonstrated on the contrast enhancement CT scan. An angiomatous stain was also visualized on the angiogram in two of the four cases. In one case, vertebral angiography showed an arteriovenous malformation in the fourth ventricle supplied by the bilateral posterior inferior cerebellar artery, and in the other, right carotid angiography revealed a faint angiomatous stain in the plexal segment of the anterior choroidal artery. Each patient underwent a successful operation on the angioma located in the fourth ventricle, the left trigone, the right trigone and the right trigone of the lateral venticle respectively. The histological diagnosis of the excised specimens was arteriovenous malformation in all four cases.Twelve reported cases with CT findings of choroid plexus angioma were reviewed, which were verified histologically. Among 16 cases including the four present ones, contrast enhancement CT (CE CT) scan was performed in 11 cases. In eight of the 11 cases (73%), a small highly density area corresponding to the site of the angioma was demonstrated on CE CT scan, while angiography revealed an angiomatous stain in only six of 14 cases (43%).Our conclusion is as follows. In cases of intraventricular hemorrhage with or without intracerebral hematoma, choroid plexus angioma should be considered as one of the causes of bleeding, even though it is supposed to be uncommon. In such cases, CE CT scan should be performed to detect the lesion of the angioma, especially in the late stage, when the hemorrhage have disappeared completely on a plain CT scan. Surgical removal of the angioma is recommended because of the high incidence of recurrent and fatal hemorrhage.