Throughout its history, Artsakh had to guard against the external threats of Neo-Ottomanism. At the present time it is especially relevant. September 27, 2020 marks escalation of the Armenian-Azerbaijani conflict over the disputed enclave of Nagorno-Karabakh – which means Artsakh in Armenian. This led to six weeks of cease fire, humanitarian disaster, which killed many people and destroyed cultural and religious heritage of Artsakh. The mountainous region is surrounded by Azerbaijani land, although populated by Armenians. Due to the political novelty of this issue, the author employed analytical and descriptive method. The acquired results demonstrate that the history repeats itself in Neo-Ottomanism, which has been a threat to Artsakh and Armenia since its emergence until the present day. In recent years, the concept of reunification with Armenia, as well as the independence of Artsakh, outlined the prospects for the future. The third solution to the conflict became the ceasefire agreement of 9 November 2020, nobly negotiated by Russia to save Armenia from military collapse. However, this solution is more painful than the status-quo. The main conclusion consists in the statement that the international community should be more vigilant and prevent the expansion of such threats.