This letter proposes a unified approach to joint iterative parameter estimation and interference cancellation (IC) for uplink CDMA systems in multipath channels. A unified framework is presented in which the IC problem is formulated as an optimization problem of an IC parameter vector for each stage and user. We also propose detectors based on a least-squares (LS) joint optimization method for estimating the linear receiver filter front-end, the IC, and the channel parameters. Simulations for the uplink of a synchronous DS-CDMA system show that the proposed methods significantly outperform the best known IC schemes.
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