CCR5-deficient Cells Research Articles

Cord blood grafts for patients with HIV?

Since CCR5 is a key co-receptor for HIV entry into cells, replacing an HIV patient's cells with CCR5-deficient cells is thought to protect the new hematopoietic/immune system from infection. In this issue of Cell, Hsuetal. show that transplanting a cord blood graft carrying the CCR5Δ32 mutation led to a durable HIV remission in a patient with HIV and leukemia.

Can Stem-Cell Transplantation with CCR5-Deficient Cells be used to Treat Patients with HIV

Can Stem-Cell Transplantation with CCR5-Deficient Cells be used to Treat Patients with HIV