Cavity Of Patients Research Articles

Investigation of the general state of oral hygiene in patients undergoing orthodontic treatment

Relevance. In patients with orthodontic structures, plaque accumulating for a long time around a non-removable device can lead to enamel demineralization, rapidly progressing to a carious cavity and the development of gingival inflammation. An important aspect of the management of such patients is measures to reduce the risk of caries and improve the effectiveness of oral hygiene. The aim of the study was to assess the level of oral hygiene in patients undergoing orthodontic treatment in groups with different methods of enamel preparation before fixing braces. Materials and methods. A randomized, controlled trial was conducted involving 60 patients aged 18–30 years. To assess the level of oral hygiene and the intensity of caries, we determined: the DMF index, the index of oral hygiene of OHI-S. The assessment of the enamel condition after removal of braces was carried out using the Adhesive Remnant Index (ARI). Universal Bond adhesive system (Tokuyama Dental), SHIELD FORCE PLUS varnish (Tokuyama Dental), double-curing adhesive fixing cement ESTECEM PLUS (Tokuyama Dental) were used to fix the braces. The effectiveness of oral hygiene was evaluated before treatment and 12 months after the start of orthodontic treatment. Results. There was a statistically significant decrease in the index of ОНІ-S in patients with ceramic and metal braces, the enamel surface of which was treated with varnish. The index of ОНІ-S before the start of the study in patients with ceramic braces was 1.5 ± 0.12, with metal ones – 1.4 ± 0.47. After 12 months, the index values were 1.6 ± 0.36 and 1.5 ± 0.46, respectively, p = 0.002. In the group of patients whose surface was not treated with varnish, the index values were statistically not significant, p > 0.05. When assessing the resistance of teeth to the development of caries using the DMF index, a statistically significant difference was also found in groups where bracket systems were fixed with pretreatment of the enamel surface with varnish. The value of the DMF index before the start of the study in the group of patients with ceramic braces was 1.7 ± 0.22, in the group with metal braces – 1.4 ± 0.14. After 12 months, the index values were 1.8±0.16 and 1.5 ± 0.23, respectively, p = 0.0012. Conclusion. The use of varnish before fixing braces helps to improve the condition of the oral cavity, which is expressed in improved hygiene, as well as in the absence of pathological changes on the enamel surface in the form of demineralization. In this regard, further studies are needed to assess the degree of influence of varnishes on the condition of the oral cavity in patients undergoing orthodontic treatment.

Compartmentalization of the Inflammatory Response in the Pericardial Cavity in Patients Undergoing Cardiac Surgery.

The systemic inflammatory response after cardiopulmonary bypass has been widely studied. However, there is a paucity of studies that focus on the local inflammatory changes that occur in the pericardial cavity. The purpose of this study is to assess the inflammatory mediators in the pericardial fluid of patients undergoing cardiac surgery. We conducted a prospective cohort study on patients undergoing aortic valve replacement. Pericardial fluid and peripheral venous blood samples were collected after the opening of the pericardium. Additional samples were obtained from peripheral blood and the pericardial fluid shed through mediastinal drains 24 and 48 h after surgery. Levels of interleukin 1α (IL-1α), interleukin 1β (IL-1β), interleukin 2 (IL-2), interleukin 4 (IL-4), interleukin 6 (IL-6), interleukin 8 (IL-8), interleukin 10 (IL-10), tumor necrosis factor-α (TNF-α), interferon-γ (IFN-γ), vascular endothelial growth factor (VEGF), monocyte chemotactic protein-1 (MCP-1), epidermal growth factor (EGF), soluble E-selectin, L-selectin, P-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) were determined in all pericardial fluid and serum samples. A total of 45 patients with a mean age of 74 years were included, of which 66% were males. Serum levels of IL-6, IL-8, and MCP-1 were significantly increased at 24 and 48 h after surgery. No significant changes were observed in the serum levels of the remaining mediators. A significant increase of postoperative pericardial fluid levels of IL-1α, IL-1β, IL-6, IL-8, IL-10, IFN-γ, VEGF, MCP-1, VCAM-1, and P-selectin was observed at 24 and 48 h after surgery. There is a robust systemic and pericardial inflammatory response after cardiac surgery on cardiopulmonary bypass. However, postoperative pericardial inflammatory activity shows a distinct pattern and is more marked than at the systemic level. These findings suggest that there is a compartmentalization of the inflammatory response within the pericardial cavity after cardiac surgery.

Targeted ultrasound examination of the edges of the abdominal cavity in patients with gallstones and concomitant bile duct diseases as a method of preventing intraoperative complications during laparoscopic cholecystectomy

Targeted ultrasound examination of the edges of the abdominal cavity in patients with gallstones and concomitant bile duct diseases as a method of preventing intraoperative complications during laparoscopic cholecystectomy

Support of the luteal phase in programs for transferring thawed embryos into the uterine cavity in patients with overweight and obesity

Introduction. Progesterone levels are a critical factor for embryo implantation in in vitro fertilization (IVF) programs, including thawed embryo transfer programs. Overweight/obese patients often have lower blood progesterone concentrations in the luteal phase during IVF cycles, which requires an individual approach to planning luteal support in this category of patients.Aim. To compare the pregnancy ratе and miscarriage rates up to 12 weeks of pregnancy in overweight/obese patients who underwent a program of transfer of thawed embryos into the uterine cavity, depending on the type and route of administration of gestagens.Materials and methods. The study included 76 overweight or obese patients. All patients were treated for infertility using a program for transferring a thawed embryo into the uterine cavity; luteal phase support was carried out either using micronized progesterone, identical to natural, – the drug Utrogestan in a daily dose of 800 mg intravaginally (40 patients), or combination therapy was prescribed – vaginal gel with progesterone 90 mg in combination with the synthetic progestin dydrogesterone in a daily dose of 30 mg, taken orally (36 patients).Results. The rates of pregnancy and miscarriage in the first trimester were comparable in both groups and did not depend on differences in luteal support.Conclusions. The formation of the luteal phase of the cycle in patients with overweight/obesity is equally effective using various forms of gestagens. The use of micronized progesterone may be preferable in patients with overweight/obesity in terms of the ability to monitor blood progesterone levels, a more favorable metabolic profile when used vaginally, and the possibility of switching to oral administration of the drug in the event of the development of adverse local events.

Association of the Genotype of TNFα with the Efficiency of the Intensive Phase of Chemotherapy and Formation of the Sizes of Destruction Cavities in Patients with Pulmonary Tuberculosis.

The interrelation between the TNFα gene polymorphism and the effectiveness of the intensive phase of chemotherapy in patients with pulmonary tuberculosis, as well as the formation of diameter of the sizes of destruction cavities was studied. It was revealed that the most adverse course of the disease and a high frequency of formation of destruction cavities are associated with the GG genotype of the TNFα gene.

Correlation between elderly patients with COPD and the impact on immunity in tuberculosis patients: A retrospective study.

The prevalence of chronic obstructive pulmonary disease (COPD) and tuberculosis (TB) is increasing globally, yet their comprehensive impact on the immune system remains underexplored. This study aimed to provide a thorough assessment of the immune status of patients with COPD and tuberculosis (TB-COPD), including their pulmonary conditions, immune cell responses, and changes in lymphocyte subpopulations. A total of 151 patients with TB-COPD patients were included, and clinical data were compared between the TB-COPD group and a group of TB patients without COPD (TB-NCOPD). Lung imaging findings and peripheral blood immune cell levels were compared between the 2 groups. Flow cytometry was used to analyze the absolute counts of lymphocyte subpopulations. The incidence of pulmonary lobe lesions and cavitation in the TB-COPD group aged 70 years or older was significantly higher than that in the control group. At the immune cell level, patients with TB-COPD showed a significant reduction in total lymphocytes, CD4+ T lymphocytes and CD4+/CD8+ ratio. Regardless of COPD status, the CD4+ T cell count in the CMV-infected group was significantly lower than that in the uninfected group (P < .05). Additionally, the CD4+/CD8+ ratio in the COPD + TB CMV + group was significantly lower than that in the uninfected group. Analysis of lymphocyte subpopulations revealed a decrease in the counts of CD4+ T lymphocytes in patients with TB-COPD, potentially associated with the chronic inflammatory state induced by COPD. The one-month treatment outcomes showed that the improvement rate in the control group was 70.58%, which was significantly higher than the 38.92% in the COPD + TB group (P < .001). We observed a significant increase in the number of pulmonary cavity patients in the TB-COPD group, suggesting that COPD may be a potential risk factor for the formation of pulmonary cavities in patients with TB. At the immune cell level, TB-COPD patients showed a notable decrease in lymphocytes and CD4+ T lymphocytes, implying that COPD combined with pulmonary TB may significantly affect the immune system, leading to a reduction in the counts of key immune cells.

MICROBIOLOGICAL CHARACTERISTICS OF THE ORAL MUCOSAIN PATIENTS WITH LICHEN PLANUS ERYTHEMATOSUS

Lichen planus is a multifactorial disease that involves immune, neuroendocrine, microbiological, and other metabolic processes associated with skin and mucosal damage. The microflora of the oral cavity in CPL SOPR was studied by E. S. Leontieva etal., 2014, the microbiocenosis of various biotopes of the oral cavity in patients with CPL SOPR was studied. The study involved 95 patients with CPL SOPR, who underwent hygienic, periodontal and microbiological research methods. The results of the degree of bacterial contamination indicate a more pronounced colonization of foci of CPL lesion by representatives of the coccoid flora: Streptococcus salivares and Streptococcus mutans, but there is no correlation between them. Isolated Streptococcus Sanguis colonies were observed in 55% of patients. In addition, fungi of the genus Candida albicans were detected in 50%, the average level of adhesion of Candida albicans strains in patients with CPL was 16.78±1.64%. The frequency of detection of fungi of the genus Candida albicans in foci of CPL lesion correlates (r=0.79) with the activity of the disease course. The significance of Candida albicans contamination is determined not so much by the degree of contamination of the lesion foci, but by such pathogenic properties of Candida albicansas the level of adhesion and the activity of germination tubes formation [1,2,3,6,11,2,3,6,11]. Authors Chuikin S. V., Akmalova G. M., Chernysheva N. D., 2014, analyzed the qualitative and quantitative microbiocenosis of the oral cavity in patients with CPL. The study included 145 patients with CPL aged 21 to 76 years, of whom 5% were men and 95% were women. The predominant form of CPL was erosive-ulcerative form (33.1%), the lowest frequency was observed in 2% of patients with bullous form. The results of the study showed that dysbiotic changes were observed with a predominance of candida infection and were found in 57.2% of the examined patients, which are observed more often in erosive-ulcerative and bullous forms of CPL. The results of the study showed that all the examined patients had microbiocenosis disorders of varying severity from dysbiotic shift to IYgrade IY dysbiosis and high sensitivity to bacteriophages was revealed. It should be noted that high sensitivity of pathogenic and opportunistic microorganisms sown in дисбактериозахoral dysbiosis was detected to цефалоспориногоcephalosporin antibiotics (100%), oxacillin (79%), gentamicin (76%), lincomycin (73%). [5,7,9,12]. A number of foreign authors Villa (TG, Sá ncheznchez-Pérez rez Á, Sieiro C., 2021) believe that microbial infection triggers an autoimmune response. Withdysbiosisof the intestinal microbiota , there is a violationof the integrity of the intestinal barrier, followed by an increase in intestinal permeability, and the penetration микроорганизмof microorganisms and their toxinов into the circulatory system. Current knowledge about this disease requires the inclusion of this disease in the list of autoimmune diseases, since the progression of CPL involves colonization of locally affected areas by bacteria, fungi or viruses that occur after damage to the oral mucosa and skin. The process of healing the disease should include eliminating microbial dysbiosis and restoring the normal microbiota of the oral mucosa, skin, and intestines. [4,6,8,10,13,14].

The value of objective methods for assessing nasal breathing function in the diagnostic algorithm for allergic rhinitis

The visual analogue score (VAS) is recommended to assess the severity of symptoms of allergic rhinitis (AR), but despite its advantages, it is a tool for subjective assessment of symptoms and often does not correlate with the true state of nasal patency. Anterior active rhinomanometry (AAR) is the method to objectify obstructive changes in the nasal cavity in patients with AR and is the most accurate method to assess nasal breathing function from a physiological and aerodynamic point of view. In addition, AAR with a decongestant test allows a differential diagnosis of the causes of nasal obstruction. Our study showed that there was no correlation between VAS and AAR scores. In addition, we found the importance of performing AAR with a decongestant test and subsequent assessment of unilateral flow and resistance parameters, which allowed us to suspect the presence of structural changes in the nasal cavity in patients with AR, as recorded as a result of anterior rhinoscopy and/or endoscopic examination. Thus, in addition to the use of VAS, it is necessary to include AAR in the diagnostic algorithm for AR, which allows not only to confirm the presence or absence of nasal breathing impairment, but also to differentiate the causes of its occurrence for the subsequent selection of the optimal management of patients with AR.

Association of polymorphism of the glutathione-s-transferase M1 gene and tumor necrosis factor alpha with the formation and size of decay cavities in patients with pulmonary tuberculosis

The aim. To study the association of polymorphic variants of the GSTM1 (E/D) and TNF-s (308G&gt;A (rs1800629) genes with the formation of decay cavity sizes in patients with pulmonary tuberculosis.Material and methods. The study group is represented by 335 patients suffering from pulmonary tuberculosis (212 people were diagnosed with pulmonary tuberculosis for the first time; 123 people with chronic pulmonary tuberculosis) aged 18 to 65 years; receiving an intensive phase of chemotherapy. To conduct molecular genetic studies; 335 people had whole blood taken from a vein into a test tube with EDTA. Genomic DNA was isolated using Arrow Blood DNA 500 reagent kits from whole blood (at the NorDiag Arrow station). After; the polymerase chain reaction was staged in real time using sets of reagents for genotyping SNPs: GSTM1 (E/D) and TNF-s (–308G&gt;A (rs1800629).Results and discussion. In patients with pulmonary tuberculosis; the genotype DD of the gene GSTM1 (E/D) and the genotype GG of the gene TNF-s –308G&gt;A (rs1800629) is most often associated with the formation of the size of decay cavities.Conclusion. It is advisable to introduce genotyping of the GSTM1 and TNF-s genes into the practice of a phthisiologist in order to predict the probability of the formation of the size of decay cavities in patients with pulmonary tuberculosis.

Development of a scoring system to predict local recurrence in brain metastases following complete resection and observation.

Postoperative stereotactic radiosurgery to the resection cavity in patients with brain metastases is guideline-recommended therapy. However, Japanese Clinical Oncology Group 0504 study showed that postoperative observation could be a therapeutic option in patients with completed resected brain metastases. We hereby investigated the incidence and risk factors for local recurrence after complete resection without immediate radiotherapy and developed a scoring system for its prediction. We included 53 patients with 54 brain metastases, who underwent complete resection between January 2016 and December 2021. We identified risk factors for local recurrence and developed a scoring system to predict it using the extracted risk factors, by assigning one point to each risk factor and calculating the total scores for each patient. We evaluated the correlation between the prognostic score and time to local recurrence. Local recurrence occurred in 37 of 54 tumors (68.5%), with a median follow-up duration of 21.0months. The median time to local recurrence was 5.1months. Univariate and multivariate analyses revealed that non-lung adenocarcinoma, infratentorial tumors, and no postoperative systemic therapy were identified as risk factors for local recurrence (non-lung adenocarcinoma, p = 0.035; infratentorial tumors, p = 0.044; and no postoperative systemic therapy, p = 0.0069). A score ≥ 2 showed a median time to local recurrence of 2.1months, starkly contrasting with 30.8months for a score ≤ 1 (p = 0.0002). Non-lung adenocarcinoma, infratentorial tumors, and no postoperative systemic therapy were risk factors for local recurrence. Our scoring system can predict local recurrence, thus potentially aiding treatment decisions.

Structural and functional changes in organs of the abdominal cavity in patients with Wilson’s disease

Structural and functional changes in organs of the abdominal cavity in patients with Wilson’s disease

FLUORESCENT DIAGNOSTIC METHOD AS A TOOL FOR COMPREHENSIVE EVALUATION OF THE HYGIENE OF NATURAL TEETH AND FIXED DENTAL PROSTHESIS CONSTRUCTIONS

This study focuses on the critical need for an oral care, especially when using fixed bridge prostheses. The analysis and impact of insufficient care for oral hygiene on the development of dental diseases and the need to develop effective methods for its assessment have been carried out. The research consists of the improvement of fluorescent diagnostics in orthopedic dentistry, as well as, in the development of an index for the assessment of the hygiene of natural teeth and fixed denture structures based on an in vivo experiment. This aims to improve the diagnosis of the condition of the oral cavity in patients with fixed prostheses, contributing to the improvement of the quality of their orthopedic treatment. Materials and methods: The use of fluorescent diagnostics with Rhodamine G dye allows to identify the presence of dental deposits under the influence of ultraviolet light. The technique involves treating teeth and dentures with a solution that enhances the visibility of dental plaque under ultraviolet light. Research results: The obtained research data confirm the high efficiency of the fluorescent technique in the detection of dental deposits, both on natural teeth and on the surfaces of fixed prostheses. Digital analysis allows you to visualize the specific graphic characteristics of the biofilm, which facilitates the adaptation of an individual approach. Conclusions: The conducted study demonstrates that the improved fluorescent method was extremely effective in determining the state of oral hygiene, effective both for the analysis of natural teeth and fixed prostheses. The proposed method allows you to determine the hygienic condition in detail, makes a significant contribution to the prevention of dental diseases and improves the optimization of medical interventions. The technique is easy to use, and the corresponding software is available for dentists. Further expansion of observations for the use of this technique in patients with a different orthopedic spectrum of needs is expected.

Morphological changes in the neuroepithelium of the olfactory zone of the nasal cavity in patients with chronic polypous rhinosinusitis

Morphological changes in the neuroepithelium of the olfactory zone of the nasal cavity in patients with chronic polypous rhinosinusitis

Evaluation of the dynamics of oral pathogenic microbiota in COVID-19 patients by genomic sequencing after application of foam with antimicrobial action

Relevance. The COVID-19 pandemic caused by the SARS-CoV-2 virus has demonstrated the critical importance of understanding the mechanisms of transmission and finding effective methods of prevention. Particular attention has been paid to the role of oral hygiene, as the oral cavity serves as a major route of transmission. Studies show that the composition of the oral microbiota can influence the course and outcome of COVID-19 disease. Therefore, there is a need to study the effects of oral antiseptics on the microbiome, which may offer new opportunities for the prevention and treatment of this disease.Objective. The aim of this study is to evaluate the effectiveness of the oral cleansing foam «Parodontol PROF» in reducing the pathogenic microflora of the oral cavity in patients with COVID-19 and to assess its effect on the risk of secondary infections.Materials and methods. The study was conducted on the basis of the Clinical Medical Centre «Kuskovo» of Russian University of Medicine. It included 450 patients with a confirmed diagnosis of COVID-19. The participants were divided into two groups: the test group used oral cleansing foam, while the control group used no additional oral hygiene. Comparative analyses of the taxonomic composition of the oropharyngeal microbiota and dental plaque before and after the use of the cleansing foam were performed.Results. The study showed that patients who regularly used the cleansing foam «Parodontol PROF» had a significant decrease in the representation of pathogens, including Mycoplasma, and an increase in the number of beneficial commensals such as Lactococcus and Lactobacillus. These changes indicate the potential efficacy of this product to improve oral hygiene and reduce the risk of secondary infections.Conclusion. The study supports the hypothesis that improving oral hygiene with specialised antiseptic agents, such as a cleansing foam, may help to reduce pathogenic microflora in the oral cavity in patients with COVID-19. This, in turn, may reduce the risk of pathogen migration into the lower respiratory tract and the development of secondary infections. The findings emphasise the importance of further research in this area and the development of comprehensive approaches to oral hygiene management in the context of infectious diseases.

Acute pancreatitis associated with pleural effusion: MDCT manifestations and anatomical basis.

Acute pancreatitis (AP) is a severe condition with complications that can impact multiple organ systems throughout the body. Specifically, the diffusion of peripancreatic effusion to the pleural cavity is a significant phenomenon in AP. However, its pathways and implications for disease severity are not fully understood. This study aims to investigate the anatomical routes of peripancreatic effusion diffusion into the pleural cavity in patients with AP and to analyze the correlation between the severity of pleural effusion (PE) and the computed tomography severity index (CTSI) and acute physiology and chronic health evaluation II (APACHE II) scoring system. 119 patients with AP admitted to our institution were enrolled in this study (mean age 50 years, 74 male and 45 female). Abdominal CT was performed, and the CTSI and APACHE II index were used to evaluate the severity of the AP, Meanwhile, the prevalence and semiquantitative of PE were also mentioned. The anatomical pathways of peripancreatic effusion draining to pleural were analyzed. Finally, the correlation relationship between the severity of AP and the PE was analyzed. In 119 patients with AP, 74.8% of patients had PE on CT. The anatomic pathways of peripancreatic effusion draining to pleural included esophageal hiatus in 33.7% of patients, aortic hiatus in 6.7% of patients and inferior vena cava hiatus in 3.37% of patients. The rating of PE on CT was correlated with CTSI scores (r= 0.449, P= 0.000) and was slightly correlated with the APACHE II scores (r= 0.197, P= 0.016). PE is a common complication of AP, which can be caused by anatomic pathways such as diaphragmatic hiatus. Due to its correlation with the CTSI score, the PE may be a supplementary indicator in determining the severity of AP.

Endometrial microbiota alteration in female patients with endometrial polyps based on 16S rRNA gene sequencing analysis.

The potential role of the endometrial microbiota in the pathogenesis of endometrial polyps (EPs) warrants further investigation, given the current landscape of limited and inconclusive research findings. We aimed to explore the microecological characteristics of the uterine cavity in patients with EPs and investigate the potential of endometrial microbiota species as novel biomarkers for identifying EPs. Endometrial samples were collected from 225 patients who underwent hysteroscopies, of whom 167 had EPs, whereas 58 had non- hyperproliferative endometrium status. The endometrial microbiota was assessed using 16S rRNA gene sequencing. We characterized the endometrial microbiota and identified microbial biomarkers for predicting EPs. The endometrial microbial diversity and composition were significantly different between the EP and control groups. Predictive functional analyses of the endometrial microbiota demonstrated significant alterations in pathways involved in sphingolipid metabolism, steroid hormone biosynthesis, and apoptosis between the two groups. Moreover, a classification model based on endometrial microbial ASV-based biomarkers along with the presence of abnormal uterine bleeding symptoms achieved powerful classification potential in identifying EPs in both the discovery and validation cohorts. Our study indicates a potential association between altered endometrial microbiota and EPs. Endometrial microbiota-based biomarkers may prove valuable for the diagnosis of EPs. Chinese Clinical Trial Registry (ChiCTR2100052746).

INDEX ASSESSMENT OF PERIODONTAL TISSUE AND ORAL HYGIENE OF PATIENTS AT THE PREOPERATIVE STAGE OF TREATMENT OF GENERALIZED PERIODONTITIS II-III DEGREE

A significant concern in modern dentistry is the increasing prevalence of periodontitis among the Ukrainian population. At present, there is a high frequency of diagnosis for initial-І degree and II-degree periodontitis in our country. However, a comprehensive comparative chronological analysis of index evaluation of periodontal tissues before the beginning of surgical treatment of generalized periodontitis of II and III degree of severity and after its completion has not yet been carried out, which determined the relevance of this study. Therefore, this study aims to address this gap in the literature.&#x0D; The aim of the study was to evaluate the state of periodontal tissues of patients at the preoperative stage of generalized periodontitis ІІ-ІІІІ degree treatment using periodontal and hygienic indices.&#x0D; Materials and Methods. Analysis of periodontal indices (PMA, PBI, Rtg-index, HEC, and tooth mobility&#x0D; score) was performed in 39 patients with GP II degree and 21 patients with GP III degree. Assessment of oral cavity hygiene by the OHI-S index was performed in patients with GP II-III degree and compared with data from 30 practically healthy people without dental diseases. The classification of M.F. Danilevsky (1994) with the additions of I.S. Mashchenko (2002) was used to evaluate the condition of periodontal tissues. Statistical processing of the research results was carried out using the software packages for statistical analysis of data from biomedical research “Microsoft Excel” and “Statistica”.&#x0D; Results and Discussion. As a result of the study, it was found that the values of periodontal indices: PMA ranged from 49.90±2.28% in patients with GP II degree to 64.25±3.22% in patients with GP III degree, p&lt;0.01; PBI in patients with GP III degree was 1.2 times lower than in patients with GP II degree (2.39±0.05 points vs. 2.86±0.07 points, p&lt;0.01; tooth mobility in patients with GP II degree was 2.00±0.10 points and was 1.5 times lower than in patients with GP III degree (2. 98±0.13 points), p&lt;0.01; the value of HEC in patients with GP III degree was 1.5 times higher than in patients with GP II degree (3.57±0.10 mm vs. 2.45±0.08 mm, p&lt;0.01); the values of Rtg-index in patients with GP ranged from 2.45±0.08 points in patients with GP II degree to 1.49±0.06 points in patients with GP III degree. According to the OHI-S index, in the control group and in patients with GP II degree, the values of the analyzed parameter were 1.82±0.13 points and 2.26±0.14 points, p&lt;0. 05, while in patients with GP III degree the value of OHI-S index (2.92±0.16 points) corresponded to poor hygiene of oral cavity and exceeded the value in the control group by 1.6 times, p&lt;0.01, and in patients with GP II degree by 1.3 times, p1&lt;0.01.&#x0D; Conclusions. Thus, the need for comprehensive treatment of GP II-III degree was emphasized by high index scores of periodontal indices, which in patients with GP III degree were significantly higher compared with similar data in patients with GP II degree, p&lt;0.01. The assessment of the hygienic state of the oral cavity in patients of both the comparison group and patients with advanced forms of GP degree the need to strengthen and improve individual, professional and motivational measures in this cohort of subjects.

Spectral Analysis of Epidermal Staphylococcus with Hemolytic Activity Isolated with Mucosa Oral Cavity in Patients with Periodontitis

Spectral Analysis of Epidermal Staphylococcus with Hemolytic Activity Isolated with Mucosa Oral Cavity in Patients with Periodontitis

АСПЕКТЫ ПРИМЕНЕНИЯ ИНДЕКСНОЙ ОЦЕНКИ СОСТОЯНИЯ ОРГАНОВ И ТКАНЕЙ ПОЛОСТИ РТА У ПАЦИЕНТОВ С ОРТОПЕДИЧЕСКИМИ КОНСТРУКЦИЯМИ ИЗ КОНСТРУКЦИОННЫХ ТИТАНОВЫХ СПЛАВОВ

The study is aimed at assessing the impact of orthopedic structures made of titanium alloys on the condition of organs and tissues of the oral cavity in patients. This study presents the results of an index assessment of the studied parameters, materials and methods of research, as well as conclusions based on the results obtained. Hygienic indices were assessed in three groups of patients with various orthopedic structures, the groups were divided depending on the structural material of the orthopedic structure, the third group was a control group, before the start of treatment and sanitation of the oral cavity, as well as after sanitation procedures carried out a month and six months later. These procedures were mandatory, as 76% of patients were found to have high plaque content upon admission to the clinic. This plaque ranged from thin to moderately dense and was visible to the naked eye. In some cases, there was a significant accumulation of plaque in the interdental spaces and gingival furrows. In patients of the first and second groups, we also evaluated the hygienic indices a month and six months after orthopedic treatment using titanium alloy structures.

Pneumatosis cystoides intestinalis: a case report and literature review

Pneumatosis cystoides was first described by Du Vernay in 1783. This is a fairly rare disease with nonspecific symptoms and CT data on pneumoperitoneum. The authors present pneumatosis intestinalis in a patient with systemic connective tissue disorder. Free gas in abdominal cavity and dilated intestinal loops were an indication for emergency surgery with subsequent resection of intestine due to signs of ischemic damage. A review of clinical cases allows us to conclude that pneumoperitoneum requires careful differential diagnosis. Free gas in abdominal cavity in patients with cystic pneumatosis is an indication for emergency surgery only in case of complicated course of disease.