You have accessJournal of UrologyBenign Prostatic Hyperplasia: Epidemiology and Natural History/Evaluation and Markers1 Apr 20111725 ONCE NOCTURIA, ALWAYS NOCTURIA? NATURAL HISTORY OF NOCTURIA IN A COMMUNITY-BASED POPULATION OF OLDER MEN Boris van Doorn, Marco Blanker, Esther Kok, Paul Westers, and Ruud Bosch Boris van DoornBoris van Doorn Utrecht, Netherlands More articles by this author , Marco BlankerMarco Blanker Groningen, Netherlands More articles by this author , Esther KokEsther Kok Utrecht, Netherlands More articles by this author , Paul WestersPaul Westers Utrecht, Netherlands More articles by this author , and Ruud BoschRuud Bosch Utrecht, Netherlands More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2011.02.1996AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Nocturia is a highly prevalent symptom. However, no data are available on the longitudinal fluctuation of nocturia (i.e. switching from nocturia to a non-nocturia state). We determined the prevalence of nocturia and its fluctuation over time, measured with frequency-volume charts (FVCs). METHODS We conducted a longitudinal, population-based study among 1,688 men aged 50 to 78 years old. Men who had undergone radical prostatectomy, a history of transurethral surgery, or had bladder or prostate cancer were excluded. At baseline (reference date: June 1995), data were obtained using FVCs, from which the nocturnal voiding frequency was determined. Nocturia was defined as 2 or more (N≥2) and 3 or more (N≥3) voids per night. Measurements were repeated during 2 follow up rounds after 2.1 and 4.2 years. We estimated the prevalence of nocturia for both definitions and analyzed the fluctuation between consecutive follow up rounds. RESULTS At baseline 1597 men (95% of the responders) completed a 3-day FVC. However, due to missing data regarding bedtime/time of rising (n=375) and due to meeting the exclusion criteria (n=108), the nocturnal voiding frequency (N) could be analyzed for 1117 men at baseline (70% of the completed charts). A total of 948 and 458 FVCs were available for the follow-up rounds at 2.1 (FU1) and 4.2 years (FU2), respectively. The prevalence of N≥2 had increased 34.6% to 43.7%; the prevalence of N≥3 had increased from 2.3% to 4.7%. The chance of having N2was significantly higher after 4.2 years. However, the chance of having N≥3 was higher after 2.1 years, but not after 4.2 years (McNemar′s test, p<0.05). The fluctuation for N≥2 showed the following pattern: Of the men who did not have N≥2 at baseline (BL), 23.9% got N≥2 at FU1. However, of these latter men, 46.0% no longer had N≥2 at FU2: Also, 36.7% of the men who did have N≥2 at BL did not have N≥2 at FU1. Of this latter group, 48.8% had N≥2 again at FU2. Of the 26.6% of men who had N≥2 at both BL and FU1, 21.6% did not have N≥2 at FU2. The percentages for N≥3 show a different pattern: of the men who did not have N≥3 at BL, 4.3% had N≥3 at FU1. However, of these latter men, 71.4% did not have N≥3 at FU-2. Also, 77.8% of the men who did have N≥3 at BL no longer had N≥3 at FU1. Of this latter group, 37.5% had N≥3 again at FU2. CONCLUSIONS Nocturia is highly prevalent but also highly fluctuant in older men in the open population when measured with FVCs. Nocturia seems to be a inconstant phenomenon which implies that once nocturia does not mean always nocturia. This fluctuation might be due to the multi-factorial aetiology and many possible causes of nocturia. © 2011 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 185Issue 4SApril 2011Page: e693 Advertisement Copyright & Permissions© 2011 by American Urological Association Education and Research, Inc.MetricsAuthor Information Boris van Doorn Utrecht, Netherlands More articles by this author Marco Blanker Groningen, Netherlands More articles by this author Esther Kok Utrecht, Netherlands More articles by this author Paul Westers Utrecht, Netherlands More articles by this author Ruud Bosch Utrecht, Netherlands More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...