Renal artery stenosis (RAS) is defined as a narrowing of one or both renal arteries ( by more then 70% to 80% to be functionally significant). It is one of the most frequent causes of secondary hypertension. The purpose of our study is to describe the therapeutic modalities of RAS. It was a descriptive retrospective study about 18 patients with RAS from 1999 to 2019. We included 8 women and 10 men with an average age of 54 years. Ten patients had more than 55 years, 2 patients had a medical family history of hypertension, 7 patients were smokers, 8 dyslipidemic, 3 diabetic and 3 were obese. Nine patients suffered from renal failure. Hypokalemia was noted in 8 cases, hyperuricemia in 3 cases. The RAS was bilateral, unilateral and unilateral with a single functioning kidney in respectively 5,11 and 2 cases. It was due to atherosclerosis in 13 cases and to fibrodysplasia in 4 cases. One patient had a RAS after clamping after a left nephrectomy for a renal tumor. Medical treatment was only prescribed for 8 patientswith angiotensin converting enzyme inhibitors or angiotensin 2 resptor antagonist, platelet agregationinhibotors and a statine. A renal artery revascularization was practiced in 10 cases: with percutaneous angioplasty in 6 cases and with surgical method in 4 cases. Two patients had a non-functional ischemic kidney that needed nephrectomy. In the short run, we had noted an inguinal hematoma which occurred after angioplasty in 1 case, one patient is dead after surgical hemorrhagic complications and another had an ischemic stroke after surgery. In the long run, a restenosis on venous bypass on single functioning kidney was noted in 2 cases. These patients were retreated with angioplasty. The evolution was favorable. The RAS is frequent. Its treatment is still a controversy between medical treatment alone or associated to revascularization.