This research paper aims to analyze the different relationships that exist between the inflation rate and economic growth, in the Congolese context, and to determine their implications in terms of economic policies. The approach is based on a combination of descriptive and econometric analyses, covering the period 1960-2018. This shows, on the one hand, the existence of a negative but insignificant link in the first three phases of the country's economic development and, on the other hand, a statically significant negative relationship with regard to the fourth phase. In addition, the study highlights a unilateral causality going from the rate of economic growth to the rate of inflation in the first and third phases. By way of recommendations, it is suggested to put in place mechanisms aimed at strengthening and consolidating the macroeconomic framework, based on the application of restrictive short-term policies and ambitious structural reforms and incentives favorable to public and private investment. It is only in this way that the increase in the DRC's gross domestic product can accelerate and be sustained, subject to a moderate or controlled variation in the general level of domestic prices.