Internal Jugular Vein Catheterization Research Articles

Application of plan-do-check-act management to improve first-attempt insertion success rates of internal jugular vein catheterization for standardized training residents in an intensive care unit

BackgroundIn the intensive care unit (ICU), internal jugular vein puncture and catheterization are basic rescue operations that physicians need to complete quickly and independently. It is necessary to improve the first-attempt success rate of internal jugular vein catheterization, shorten the catheterization duration and reduce the incidence of complications for standardized training residents (STRs).ObjectiveTo improve first-attempt insertion success rates of internal jugular vein catheterization for STRs.MethodsBased on the PDCA cycle management method and current situation investigation, the PDCA management objectives were set, and the implementation content, monitoring items and continuous improvement plan were formulated. The data of residents who were trained in the ICU of Fangcun Hospital, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, from January 2016 to April 2016 and managed by the PDCA cycle (PDCA group), were compared with the data of residents trained in the same department from August 2015 to November 2015 before the implementation of PDCA (historic control group), the first-attempt success rate of puncture and catheterization, the duration of puncture and catheterization, and the incidence of complications were analysed.ResultsThirty-six cases of internal jugular vein catheterization were performed by the PDCA group, 21 cases (58%) were performed by residents in the third year of standardized training, and 15 cases (42%) were performed by residents in the second year of standardized training. Compared with the historic control group, there was no significant difference in the seniority of residents (X2 = 0.240, P = 0.625) or the ‘majors of the residents (X2 = 1.306, P = 0.835). The first-attempt success rate of puncture in the PDCA group was 94% (34/36), which was significantly higher than that of the historic control group (55% (11/20) (P = 0.001). In the PDCA group, the first-attempt success rate of puncture among third-year standardized training residents was 95% (20/21), and the first-attempt success rate in the second-year was 93% (14/15), which were significantly higher than the corresponding rates of 62% (8/13) and 43% (3/7) respectively, in the historic control group (all P = 0.021). The duration of catheterization was [4 (3,5)] min after PDCA, which was significantly shorter than that in the historic control group [9 (6.25,13.00)] min (Z = − 5.214, P < 0.001). The incidence rate of complications in the PDCA group was 0% (0 /36), which was significantly lower than the rate of 20% (4 / 20) in the historic control group (P < 0.013).ConclusionPDCA cycle management can help improve the first-attempt success rate of internal jugular vein puncture and catheterization, shorten the duration of puncture and catheterization, and reduce the incidence of complications. The idea and method of PDCA cycle management can be applied to other training and management protocols for STRs.

Comparison of Femoral and Internal Jugular Vein Catheterisation Trends in Sick Infants.

To compare two different ways of central venous access in newborns regarding complications and success rates. Descriptive study. Third-level Newborn Intensive Care Units in Kahramanmaras Sutçu Imam University Health Practice and Research Hospital and Megapark Private Hospital, Turkey, between July 2017 and May 2019. The data of 132 and 81 patients who underwent tunnelled femoral vein (FV) and percutaneous internal jugular vein (IJV) access procedures, respectively, for advanced medical management were reviewed. Planned procedures performed in an operating room under general anaesthesia were included in the study. Demographic data of infants, kind and the number of complications, and findings in clinical follow-up were recorded. There were similar success rates between techniques. No complication requiring intervention occurred during the placement of the FV catheters. Four procedures were interrupted due to periprocedural complications requiring intervention in the placement of IJV catheters. The median value of catheter duration was 25.5 (15-36.75) and 14 (9-20) days in FV and IJV group, respectively, and the difference is significant (p<0.001). Lower infectious complications (p=0.008) were detected in the use of FV catheters. Similar success rates were found for both ways of central venous access. IJV stent's intrathoracic complications can be too severe for sick infants to cope with. FV stents can also be used in infants with well-tolerated complications. Further studies should confirm the low infectious complication rate of this study in FV catheters. Femoral vein, Internal jugular vein, Central venous access, Catheter-related infection, Infants.

Acute change of cardiac autonomic regulations after thermal and non-thermal pulmonary vein ablation

Abstract Funding Acknowledgements Type of funding sources: None. Background Pulmonary vein isolation (PVI) by thermal energy (radiofrequency energy or cryoenergy) results in collateral ganglionic plexi ablation. On the contrary, pulsed electric field (PEF) energy presumably spares neural tissue. Purpose We investigated and compared the effect of PVI on parasympathetic input into the sinus node (SAN) and AV node (AVN) when four different ablation strategies were used. Methods A study enrolled 49 patients who underwent PVI in general anesthesia (age: 57 ± 13 years, 71% males). In 17 patients, point-by-point radiofrequency energy delivery by the irritated-tip catheter was used for ablation while 7 patients were ablated using a second-generation cryoballoon catheter. In 7 patients, PEF energy was delivered using a single-shot Farawave catheter while 18 patients were ablated using Sphere9 lattice-tip catheter (Affera, Inc.); both subgroups with manufacturer-specific PEF settings. Before and after PVI, the responsiveness of the SAN and AVN was assessed by extracardiac vagal nerve stimulation (ECVS) via a diagnostic catheter in the right internal jugular vein. Five-second stimulation trains were delivered with a frequency of 50 Hz, pulse width of 0.05 ms, and output of 1 V/kg (&amp;lt;70V) both in sinus rhythm and during atrial pacing. Substantial reduction of response to ECVS was arbitrarily defined as a maximum induced pause of &amp;lt;1.5 seconds. Results At baseline, physiological response to ECVS (long sinus arrest and/or AV block) was demonstrated. After PVI, a substantial reduction of SAN response was observed in 21/24 (88%) patients after thermal PVI and 7/25 (25%) patients after non-thermal PVI (P = 0.0001). Similarly, a substantial reduction of AVN response was observed in 21/24 (88%) patients after thermal PVI and 9/25 (36%) patients after non-thermal PVI (P = 0.0003). The Figure shows on the continuous scale the post-PVI pauses in sinus rhythm (maximum P-P interval) and atrial pacing (maximum R-R interval) induced by ECVS. Conclusion Vagal responses of SAN and AVN are preserved in most AF patients after non-thermal PVI. This contrasts with the much stronger effect of thermal PVI. Whether this may influence the clinical outcome of AF ablation procedures remains to be investigated in future studies.

Application of ultrasound-guided central venous catheterization at various sites in infants with shock

To study the clinical characteristics of ultrasound-guided central venous catheterization at various sites in infants with shock, and to explore how to quickly select the site for central venous puncture in infants with shock. The medical data of 112 infants who were diagnosed with shock and underwent central venous catheterization in the Pediatric Intensive Care Unit, Dongguan Children's Hospital Affiliated to Guangdong Medical University, from January 2016 to December 2020 were reviewed retrospectively. The patients were divided into an ultrasound group (n=70) and a body surface location group (n=42) according to whether the catheterization was carried out under ultrasound guidance. The application of ultrasound-guided catheterization at various sites in infants was summarized and analyzed, and the success rate of one-time puncture, overall success rate, catheterization time, and complications were compared between these sites. Compared with the body surface location group, the ultrasound group had a significantly higher success rate of one-time puncture, a significantly shorter catheterization time, and a significantly reduced incidence rate of complications in internal jugular vein and femoral vein catheterizations (P<0.05). In the ultrasound group, the proportion of internal jugular vein catheterization was the highest (51%, 36/70), followed by femoral vein catheterization (33%, 23/70), and subclavian vein catheterization (16%, 11/70). For the comparison between different puncture sites under ultrasound guidance, internal jugular vein catheterization showed the shortest time of a successful catheterization [5.5 (5.0, 6.5) minutes] (P<0.05). There was no significant difference in the incidence rate of complications among the different puncture sites groups (P>0.05). In infants with shock, ultrasound-guided internal jugular vein catheterization can be used as the preferred catheterization method for clinicians.

Ultrasound-Guided vs. Landmark Method for Subclavian Vein Catheterization in an Academic Emergency Department

BackgroundUltrasound guidance has been shown to decrease complication rates and improve success for internal jugular and femoral vein catheterization in the emergency department (ED). However, the current data on the efficacy and safety of ultrasound-guided subclavian vein catheterization has failed to provide support for similar conclusions. ObjectiveTo determine if ultrasound-guided subclavian vein catheterization is safer and more efficacious than the traditional landmark method in an ED setting. MethodsA prospective randomized trial was conducted from April 2004 through June 2009 in an urban tertiary care academic ED with an annual census of >50,000 patients. Four primary data endpoints were calculated: 1) overall success for both resident and attending physicians; 2) number of attempts by each group of providers; 3) complication rate with each method; and 4) time to which the subclavian line was obtained. ResultsEighty-five patients were enrolled in the study. The ultrasound method was more successful in obtaining subclavian catheter placement when compared with the landmark method. When comparing successful cannulation attempts in both groups, the ultrasound group showed a statistically significant longer time to success when compared with the landmark group. There was no difference in the success or complication rates between residents and attending physicians. There was no significant difference in complications rates between ultrasound-guided and landmark methods. ConclusionUltrasound-guided subclavian vein catheterization was found to be associated with a higher overall success rate compared with the landmark method with no significant difference with respect to complication rate in an ED setting. © 2022 Elsevier Inc.

CA-537-01 ACUTE CHANGE OF CARDIAC AUTONOMIC REGULATIONS AFTER THERMAL AND NON-THERMAL PULMONARY VEIN ABLATION

Pulmonary vein isolation (PVI) by thermal energy (radiofrequency energy or cryoenergy) results in collateral ganglionic plexi ablation. On the contrary, pulsed electric field (PEF) energy presumably spares neural tissue. We investigated and compared the effect of PVI on parasympathetic input into the sinus node (SAN) and AV node (AVN) when four different ablation strategies were used. A study enrolled 49 patients who underwent PVI in general anesthesia (age: 57 ± 13 years, 71% males). In 17 patients, point-by-point radiofrequency energy delivery by the irritated-tip catheter was used for ablation while 7 patients were ablated using a second-generation cryoballoon catheter. In 7 patients, PEF energy was delivered using a single-shot Farawave catheter (Boston Scientific) while 18 patients were ablated using Sphere9 lattice-tip catheter (Affera, Inc.); both subgroups with manufacturer-specific PEF settings. Before and after PVI, the responsiveness of the SAN and AVN was assessed by extracardiac vagal nerve stimulation (ECVS) via a diagnostic catheter in the right internal jugular vein. Five-second stimulation trains were delivered with a frequency of 50 Hz, pulse width of 0.05 ms, and output of 1 V/kg (<70V) both in sinus rhythm and during atrial pacing. Substantial reduction of response to ECVS was arbitrarily defined as a maximum induced pause of <1.5 seconds. At baseline, physiological response to ECVS (long sinus arrest and/or AV block) was demonstrated. After PVI, a substantial reduction of SAN response was observed in 21/24 (88%) patients after thermal PVI and 7/25 (25%) patients after non-thermal PVI (P = 0.0001). Similarly, a substantial reduction of AVN response was observed in 21/24 (88%) patients after thermal PVI and 9/25 (36%) patients after non-thermal PVI (P = 0.0003). The Figure shows on the continuous scale the post-PVI pauses in sinus rhythm (maximum P-P interval) and atrial pacing (maximum R-R interval) induced by ECVS. Vagal responses of SAN and AVN are preserved in most AF patients after non-thermal PVI. This contrasts with the much stronger effect of thermal PVI. Whether this may influence the clinical outcome of AF ablation procedures remains to be investigated in future studies.

Comparison of the ultrasonography guided catheterization with the landmark technique in internal jugular vein catheterization.

Objective: To determine the differences in using the ultrasound guided technique as compared to the landmark technique for the cardiac catheterization procedures. Study Design: Cross-sectional study. Setting: Civil Hospital, Karachi. A Large Tertiary Care Hospital in Karachi, Pakistan. Period: November 2018 to November 2019. Material &amp; Methods: Patients were divided into two groups, those who underwent catheterization through the landmark procedure and those who had the ultrasound guided procedure done. Various clinical and laboratory investigations were performed and recorded for the patients. The inclusion criteria was all the patients whose complete data was available in our archives, between the ages of 18 and 80 years, and belonging to the ASA Classification I to III, an international normalized ratio (INR) of &lt;1.5 and platelet counts of &gt;50,000 mm3. Results: The study population n= 600 patients, the mean age of patients was 65.2 +/- 10.6 years. We did not find any statistically significant differences in the age comparisons of the two groups, having a P-value of 0.3. Similarly, no difference was found in between genders, having a P-value of 0.8. When it comes to the duration of the bypass procedure there was no significant difference, the p value was 0.7. The success rate of the procedure was 89.79% in the landmark group and 98.07% in the ultrasound group, the P-value was significant at 0.04 respectively. Conclusion: The ultrasound-guided central venous catheterization is an effective and safer option when compared to the landmark technique.

Compare the Efficacy and Safety of Modified Combined Short and Long Axis Method versus Oblique Axis Method for Right Internal Jugular Vein Catheterization in Adult Patients (The MCSLOA Trial): Study Protocol of a Randomized Controlled Trial.

BackgroundUltrasound-guided internal jugular vein (IJV) catheterization has become a standard procedure as it yields a higher success rate and fewer mechanical complications compared with an anatomical landmark technique. There are several common methods for ultrasound guidance IJV catheterization, such as short-axis out-of-plane, long-axis in-plane and oblique axis in-plane, but these technologies are still developing. It is important to further study the application of different ultrasound-guided IJV puncture techniques and find an effective and safe ultrasound-guided puncture technique.MethodsA China randomized, open-label, parallel, single center, positive-controlled, non-inferiority clinical trial will evaluate 190 adult patients undergoing elective surgery and need right jugular vein catheterization. Study participants randomized in a 1:1 ratio into control and experimental groups. The control group will take the oblique axis in-plane method for IJV catheterization. The experimental group will take the Modified combined short and long axis method. The primary endpoint of the trial is the rate of one-time successful guidewire insertion without posterior wall puncture (PWP). Secondary endpoints are the number of needle insertion attempts, the total success rate, the procedure time, and mechanical complications.ConclusionThis randomized controlled trial will evaluate the effectiveness and safety of Modified combined short and long axis method and oblique axis in-plane method for right IJV catheterization in adult patients.

Short peripheral intravenous cannula and straight-tip guide wire in ultrasound-guided neonatal central venous catheterization

Inserting a J-tip guide-wire into a vein's lumen is often difficult when using the Seldinger or modified Seldinger technique for central venous catheterization (CVC) in newborns. This study was designed to compare the efficacy and safety of guide-wire insertion using the combination of a short peripheral intravenous cannula with a straight-tip guide-wire vs. a needle with a J-tip guide-wire for ultrasound-guided (USG) cannulation of the internal jugular vein (IJV) in newborns using an in-plane technique. One hundred and thirty newborn patients (weight, 1.4-5.2 kg) scheduled for selective or emergency surgery, were randomly assigned to either the needle group (combined with a J-tip guide-wire) or cannula group (combined with a straight-tip guide-wire). The primary outcome was the rate of successful guide-wire insertion on the first attempt. The puncture attempts, catheter placement attempts, and mechanical complications were also compared between the groups. The rate of successful guide-wire insertion on the first attempt was higher in the cannula group (97%) than in the needle group (76%) (p < 0.05, χ2 = 11.233). Moreover, fewer insertion attempts were needed in the cannula group (1.0 ± 0.2) than in the needle group (1.7 ± 1.1) (p < 0.05, 95% CI [0.449, 1.028]). The time to successful guide-wire insertion was shorter in the cannula group (63 ± 32 s) than in the needle group (92±50 s) (p < 0.05, 95% CI [14.024, 43.063]). No differences were found about other catheterization parameters and complications between the groups. The short peripheral cannula combined with a straight-tip guide-wire was superior to the needle combined with a J-tip guide-wire for USG newborn IJV catheterization in terms of successful guide-wire insertion on the first attempt and overall number of insertion attempts.

Ultrasound Guidance for Internal Jugular Vein Catheterization: Don't Forget the Basics.

Ultrasound Guidance for Internal Jugular Vein Catheterization: Don't Forget the Basics.

Evaluation of the ideal length of the Seldinger needle for internal jugular vein catheter placement

Placement of central venous catheters (CVC) into the internal jugular vein represents a routine clinical intervention. The periprocedural complication rate ranges from 5 to 20% and can be reduced by ultrasound guidance, training of residents and other measures. We aimed to proof that the average Seldinger needle is too long, increasing the risk of periprocedural injury, best epitomized in the stellate ganglion injury/irritation. The first part of the study was an online market analysis to investigate the standard needle length currently offered as part of the CVC placement sets. The second part of the study involved 35 hospitalized patients (14 female; median age 74.5 years). In those the distance between the skin and the internal jugular vein as well as the diameter of the internal jugular vein was measured by ultrasound in both, supine position as well as 45° semi-sitting position. In the third part of the study 80 body donors (45 female; median age 83.0 years) preserved by the ethanol/formaldehyde method were studied. In those the distance and angle between the typical landmark for insertion of the Seldinger needle for internal jugular vein catheter placement to the stellate ganglion was measured. The median [interquartile range] Seldinger needle length was 7 [4.0–10.0] cm. In the examined patients the maximum distance between the skin and the internal jugular vein was 1.87 cm. The minimum distance was 0.46 cm and the median distance averaging supine and 45° position was 1.14 [0.94–1.31] cm. Regarding the body donors the median distance from the insertion point of the internal jugular vein to the stellate ganglion was longer in men 5.5 [4.95–6.35] cm than in women 5.2 [4.7–5.9] (p = 0.031 unpaired t-test). With 7 cm average length the Seldinger needle currently sold as part of CVC sets is long enough to physically reach the stellate ganglion, not to mention more proximal structures. A shorter needle length would be sufficient to reach the internal jugular vein even in obese patients and with a small insertion angle while minimizing the possibility to cause severe injury as structures like the pleura and the stellate ganglion could not be reached by shorter needles.

Malposition of Double-Lumen Hemodialysis Catheter via Internal Jugular Vein Catheterization with Complicated Hemomediastinum

Malposition of Double-Lumen Hemodialysis Catheter via Internal Jugular Vein Catheterization with Complicated Hemomediastinum

Inadvertent through-and-through internal jugular vein penetration and intracarotid placement of a central venous catheter: Microsurgical retrieval technique and operative video

Inadvertent carotid cannulation is a rare complication of internal jugular vein (IJV) catheterization, occurring in less than 1% of cases. Given the significant risk of embolic stroke, urgent catheter removal is indicated. In this technical report and operative video, we present our microsurgical technique for the retrieval and removal of an inadvertently placed, transjugular intracarotid central venous catheter (CVC). A 52-year old man presented with sepsis and hemodynamic lability. An attempt to catheterize the left IJV resulted in inadvertent intracarotid CVC placement, following a through-and-through transjugular path. An open microsurgical approach was used to retrieve the CVC and secure local hemostasis, resulting in excellent outcome. Though generally more invasive than percutaneous and endovascular approaches, open surgical retrieval of misplaced intracarotid CVC leads to consistently excellent outcomes, rendering it the preferred approach in the setting of complex catheter trajectories. The technical note and surgical video presented here can serve as a step-by-step guide for performing this procedure, both safely and effectively.

The risk of fatal bleeding complications in jugular catheterization in patients with coagulopathy: A retrospective analysis of death cases in closed claims and the Medical Accident Investigating System in Japan.

BackgroundTo prevent recurrence of medical accidents, the Medical Accident Investigating System was implemented in October 2015 by the Japan Medical Safety Research Organization (Medsafe Japan) to target deaths from medical care that were unforeseen by the administrator. Medsafe Japan analyzed the 10 cases of central venous catheterization-related deaths reported in the system and published recommendations in March 2017. However, the particular emphasis for the prevention of central venous catheterization-related deaths is unclear.MethodsThis study aimed to identify the recommendation points that should be emphasized to prevent recurrence of central venous catheterization-related deaths. We assessed central venous catheterization in 8530 closed-claim cases between January 2002 and December 2016 covered by the medical insurer Sompo-Japan. Moreover, we compared central venous catheterization-related death in closed-claim cases with death in reported cases.ResultsThe background, error type, anatomic insertion site, and fatal complication data were evaluated for 37 closed-claim cases, of which 12 (32.4%) were death cases. Of the 12 closed-claim cases and 10 reported cases, 9 (75.0%) closed-claim cases and 9 (90.0%) reported cases were related to vascular access. Among these, 5 closed-claim cases (41.7%) and 7 reported cases (77.8%) were related to internal jugular vein catheterization (p = 0.28). Coagulopathy was observed in 3 (60.0%) of 5 closed-claim cases and 6 (85.7%) of 7 reported cases.ConclusionsThe risk of internal jugular catheterization in patients with coagulopathy must be carefully considered.

Катетеризация внутренней яремной вены у детей. Безопасный сосудистый доступ

The paper discusses the topical issues of prevention of complications during puncture and catheterization of internal jugular veins (IJV) in children. Variants of anatomical organization of major vessels in the region of IJV puncture identified through ultrasound examination both at the time of screening and prior to IJV catheterization, which explain the high risk of complications during this manipulation, are described. The main directions for prevention of possible perforation of the vein posterior wall entailing injuries of anatomical substructures (branches of the carotid artery, vagus nerve) are given. The proprietary methodology of safe step-by-step catheterization of principal veins is provided. Reduction of the risk of complications during internal jugular vein catheterization thanks to usage of all steps described above has been convincingly demonstrated. Key words: intensive care in children, ultrasound examination, venous access, internal jugular vein catheterization

Ulcerating Stasis Dermatitis of the Forearm Associated With Arteriovenous Graft and Central Vein Stenosis

Stasis dermatitis is a pathologic condition of the skin that most commonly occurs in the lower limb, where it is caused by chronic venous insufficiency. Stasis dermatitis of the upper limb is rare. A 45-year-old male, resident in Angola, presented to the emergency department with an ulcer encompassing the entire left forearm. Past medical history comprised arterial hypertension and end stage renal disease treated with hemodialysis. Dialysis access consisted of a left brachial-basilic AV graft obtained 4 years before. The patient also reported that a right internal jugular vein catheter was used previously during the maturation of the left brachial-basilic AV graft. Stenosis of the left brachiocephalic vein was documented at angiography. Angioplasty was performed, with complete resolution of the wound 2 months after admission. The differential diagnosis of extensive ulcer of the forearm must include neoplasms, cellulitis, and/or deep tissue infection with secondary ulceration, but it is also important to maintain suspicion for venous stasis syndrome as a rare but possible cause of these lesions.

Thoracic Duct Injury associated with Ultrasound guided Left Internal Jugular Vein Tunneled Cuffed Catheter Insertion

Thorcic duct injury leading to chylothorax is a rare but important complication following left internal jugular vein catheterization.. In the absence of serious clinical symptoms, conservative treatment with close patient monitoring is the preferred approach. Here we report two such cases of thoracic duct injury following jugular vein catheterisation, which were managed conservatively.

Safety of Bedside Placement of Tunneled Hemodialysis Catheters in the Intensive Care Unit: Translating from the COVID-19 Experience.

Background: Critically ill patients with coronavirus disease 2019 (COVID-19) and kidney dysfunction often require tunneled hemodialysis catheter (TDC) placement for kidney replacement therapy, typically under fluoroscopic guidance to minimize catheter-related complications. This entails transportation of patients outside the intensive care unit to a fluoroscopy suite, which may potentially expose many healthcare providers to COVID-19. One potential strategy to mitigate the risk of viral transmission is to insert TDCs at the bedside, using ultrasound and anatomic landmarks only, without fluoroscopic guidance. Methods: We reviewed all COVID-19 patients in the intensive care unit who underwent right internal jugular TDC insertion at the bedside between April and December 2020. Outcomes included catheter placement-related complications such as post-procedural bleeding, air embolism, dysrhythmias, pneumothorax/hemothorax, and catheter tip malposition. TDC insertion was considered successful if the catheter was able to achieve blood flow sufficient to perform either a single intermittent or 24 h of continuous hemodialysis treatment. Results: We report a retrospective, single-center case series of 25 patients with COVID-19 who had right internal jugular TDCs placed at the bedside, 10 of whom underwent simultaneous insertion of small-bore right internal jugular tunneled central venous catheters for infusion. Continuous veno-venous hemodialysis was utilized for kidney replacement therapy in all patients, and a median catheter blood flow rate of 200 mL/min (IQR: 200–200) was achieved without any deviation from the dialysis prescription. No catheter insertion-related complications were observed, and none of the catheter tips were malpositioned. Conclusions: Bedside right internal jugular TDC placement in COVID-19 patients, using ultrasound and anatomic landmarks without fluoroscopic guidance, may potentially reduce the risk of COVID-19 transmission among healthcare workers without compromising patient safety or catheter function. Concomitant insertion of tunneled central venous catheters in the right internal jugular vein for infusion may also be safely accomplished and further help limit personnel exposure to COVID-19.

Central venous catheter-related thrombosis in pediatric surgical patients: A prospective observational study.

Perioperative central venous catheters are required but may be associated with various complications. The purpose of our study was to assess the incidence and perioperative risk factors for catheter-related internal jugular vein thrombosis in pediatric surgical patients. This prospective observational study included children under 6years of age who were scheduled to undergo central venous catheterization of the right internal jugular vein under general anesthesia. A central venous catheter was inserted under real-time ultrasound guidance. An investigator examined for thrombosis using ultrasonography at predetermined time points. The primary aim was the incidence of catheter-related thrombosis from insertion until the 5th day postoperatively or the removal of the central venous catheter. The secondary aim was the determination of the risk factors for thrombosis. Eighty patients completed the study. Internal jugular vein thrombi were found in 31 patients (38.8%, 95% CI 28.0-49.4). On multiple logistic regression analyses, the number of insertion attempts was the only influencing factor for catheter-related thrombosis (p<.001). More than two insertion attempts increased the risk of thrombosis (odds ratio 5.6; 95% CI 1.7 - 18.7, p=.004). Anesthesia time (p=.017; mean difference 166.4min; 95% CI 55.7-277.1), intraoperative red blood cell transfusion (p=.001; median difference 21.1ml kg-1 ; 95% CI 6.6-34.4), and intensive care unit stay (p=.001; median difference 100.0h; 95% CI 48-311) differed between patients with transient thrombosis and those with thrombosis lasting for more than 3days. Internal jugular vein thrombosis was frequently detected by ultrasound following central venous catheterization in pediatric surgical patients. Multiple insertion attempts may be associated with the incidence of thrombosis. The clinical relevance of thrombi detected via ultrasound surveillance has not been determined.

Long Term Follow up of Neonatal Internal Jugular Vein Catheterization: Patency and Thrombosis

Long Term Follow up of Neonatal Internal Jugular Vein Catheterization: Patency and Thrombosis