Faced with the increasing number of flights, efficient and orderly operations have become a critical issue for busy airports. The closely spaced parallel runway paired approach technology has been proven to be an effective solution for increasing runway capacity and operational efficiency. This research focuses on determining the safety separation between paired aircraft, particularly the collision safety limit. This study refines the kinematic modeling process by constructing a three-dimensional kinematic model and advancing the starting point of paired approach, making the simulation process more aligned with reality. Subsequently, the Monte Carlo simulation method is applied, integrating the kinematic model and considering collision risks to simulate the entire paired approach process. Multiple scenarios are created, and simulation experiments are conducted to determine the safety separation between the two paired aircraft. Finally, by adjusting parameter settings and taking the example of the two closely spaced parallel runways at Chongqing Jiangbei International Airport, the correlation between various influencing factors and the safety separation is analyzed. Different scenarios are simulated 100,000 times each, and the results show that the speed difference between the two paired aircraft has the most significant impact on the safety separation, followed by the paired approach mode and runway centerline spacing. The wake turbulence category matching has a minimal effect on the safety separation. The results provide a theoretical basis for airports with closely spaced parallel runways to further reduce the separation between paired aircraft, thereby enhancing airport capacity and runway operational efficiency.