Poultice Research Articles

Sub-chronic safety evaluation of aqueous extract of Alangium salvifolium (L.f.) Wangerin leaves in rats.

Conventionally, the juice and extract of Alangium salvifolium leaves have been used for the treatment of diabetes, wound healing, dog bite, and as a poultice in rheumatism. To carry out the sub-chronic toxicity and thereafter safety evaluation of A. salvifolium leaves. The aqueous extract of A. salvifolium leaves was administered orally at the doses of 200, 400, and 800 mg/kg/day for 90 days. All the animals were observed daily for general behavior, changes in body weight, food, and water consumption. At the end of the treatment period, biochemical and hematological parameters were analyzed; and the animals were sacrificed for histopathological examination of heart, lungs, liver, and kidney. The general behavior and water intake were normal in all the rats. The increase in body weight was observed in female rats of all the groups while body weight was decreased in high dose group animals of both sexes. Hematological parameters were not disturbed by the continuous use of extract. A significant decrease in glucose level was observed in intermediate- and high-dose group animals while urea and creatinine level were significantly high in animals of high-dose group. Although histopathological examination of most of the organs exhibited no structural changes, some tubal damage in kidneys was observed in high-dose group animals. The high dose of extract has shown mild signs of toxicity on kidney function test, but no toxic response was observed on hematological and liver biochemical parameters. The extract also exhibited hypoglycemic potential.

Clinical application of Betamethasone-calcium hydroxide paste in one-time root canal treatment

Objective To study the clinical application and efficacy of betamethasone-calcium hydroxide paste in one-time root canal treatment. Methods 160 teeth were randomly divided into the experimental group （betamethasone-calcium hydroxide） and the control group （cortisomol） with 80 cases in each group. Two kinds of cataplasm were sent into the root canals by using screw conveyor in each group after root canal preparation and drying. Then we filled the canals tightly with gutta-percha by lateral condensation. Permanent filling were operated after X-ray determination of canal filling. 3 days later, pain of the tooth was recorded. 6 and 12 months later, the cure rate of each group was observed. Results The pain rates and the cure rates were no significant difference between two groups （P〉0.05）. Conclusion Betamethasone-calcium hydroxide cataplasm and cortisomol have the basical same clinical effect in one-time root canal treatment. Key words: Betamethasone; Calcium hydroxide; Cortisomol; One-time root canal treatment

Unani system of medicine and development of its materia medica

Unani system of medicine and development of its materia medica

Preparation and Quality Evaluation of Xiaochuan cataplasm

Objective To study the influence of the preparation and quality control of Xiaochuan cataplasm on its drug action. Methods Xiaochuan cataplasm was prepared with hydrosoluble polymers matrix. A sequence of tests such as adhesive force test, recontour test, paste-content test, cold-resistance test, heat-resistance test, toxicity and pharmacodynamic action tests were performed on this drug. Results Xiaochuan cataplasm contains a sound volume of medicine, and shows good adhesive property, no sensibilization and stimulation, and notable drug action. Conclusion The results demonstrate that the preparation craft of Xiao-chuan cataplasm is reasonable and practicable., the quality is controllable and the method is a safe and effective transdermal drug delivery system. Key words: Winter disease being cared in summer ; Application therapy of Xiaochuan ointment ; Xiao-chuan cataplasm ; Preparation Craft ; Quality evaluation ; Pharmacodynarnic action ;

Effect of penehyclidine on small intestinal motility in mice and rats

Objective To investigate the effect of penehyclidine on small intestinal propulsion in mice and plasma level of motilin in rats.Methods The experiment was performed in 2 parts. In experiment Ⅰ , twenty-four healthy Kunming mice of both sexes weighing 17-22 g were randomly divided into 3 groups (n = 8 each): group control (C1), group Ⅱ received intraperitoneal (IP) atropine 0.3 mg/kg (A1) and group Ⅲ received IP penehyclidine 0.3 mg/kg (P1). Nutritional semi-solid cataplasm 0.8 ml was given into the stomach at 15 min after IP injection. The mice were killed 20 min later. The abdomen was cut open. The length of the small intestine and the distance between the pylorus and the nutritional semi-solid cataplasm in the small intestine were measured. The rate of intestinal propulsion was calculated. In experiment Ⅱ , twenty-four Wistar rats of both sexes weighing 170-220 g were randomly divided into 3 groups (n=8 each);group Ⅰ control (C2);group Ⅱ received IP atropine 2 mg/kg (A2) and groupⅢ received IP penchyclidine 2 mg/kg (P2). Blood samples were taken at 30 min after IP drug administration for determination of plasma motilin concentration (by radio-immuno-aasay). Results The rate of small intestinal propulsion was significantly lower in group A1 than in group C1. There was no significant difference in the intestinal propulsion between group C1 and P1. The plasma concentration of motilin was significantly lower in group A2 than in group C2 but there was no difference in plasma motilin concentration between group P2 and C2. The plasma concentration of motilin was significantly lower in group A2 than in group P2. Conclusion Penehyclidine has no effect on small intestine motility. Key words: Quinuclidines; Gastrointestinal motility; Intestine, small

Enzymes in Solvent Conditioned Poultices for the Removal of Starch-based Adhesives from Iron Gall Ink Corroded Manuscripts

Des recherches ont ete effectuees concernant deux possibilites differentes visant a retirer les contrecollages difficilement solubles du papier sensible a l'eau qui avaient souffert de la corrosion a l'encre gallique en milieu partiellement aqueux. Les experiences ont ete realisees sur des echantillons de contrecollages modifies, prepares a partir de farine de ble et donc de pâte difficilement soluble d'amidon, en utilisant des gels d'amylase partiellement aqueux contenant du solvant methoxy-ethanole (methyl cellosolve). Sur la base des resultats obtenus en utilisant des gels d'oxyde de polyethylene contenant des additifs d'amylase et de methoxyethanole (methyl cellosolve) pour retirer les contrecollages administres aux echantillons testes, des methodes d'application ont ete developpees et analysees. Une des methodes d'application a ete modifiee pour pouvoir etre utilisee sur des echantillons de plus grandes dimensions. Par ailleurs un systeme a ete mis en place afin d'utiliser le gel d'amylase sans se servir d'additif de solvant (methyl cellosolve) pour le contrecollage. Aucun changement indesirable n'a pu etre observe sur les echantillons utilises. Enfin cette methode a pu etre appliquee sur un objet authentique.

薬剤漏出に対する罨法の効果についての実験的研究

薬剤漏出に対する罨法の効果についての実験的研究

“No mess” poultice offered

“No mess” poultice offered

Flaxseed Poultices

Flaxseed Poultices

Flaxseed Poultices

Flaxseed Poultices

Cataplasm of Kaolin

Cataplasm of Kaolin

Mustard Poultices Applied Extensively to the Surface

Mustard Poultices Applied Extensively to the Surface

21. Poultices in Inflammation of the Great Cavities

21. Poultices in Inflammation of the Great Cavities

32. On the employment of tobacco as a cataplasm

32. On the employment of tobacco as a cataplasm