Catalytic Microreactor Research Articles

Universal, Time-Cost-Effective, and Inside-Out Strategy for Synthesis of Plant-Based Flow Catalysis Microreactors.

The utilization of plant-based flow catalytic microreactors has been increasingly gaining traction in the fields of water treatment, energy generation, and biotechnological science due to their inherent channel structures, renewable properties, and environmentally friendly nature. The conventional outside-in strategy for synthesizing plant-based monolithic microreactors typically entails prolonged hydrothermal modification, extensive chemical usage, or energy-intensive equipment. The present study presents a universal inside-out strategy for the rapid synthesis of monolithic catalytic microreactors derived from plant materials. This approach enables the direct formation of catalytic metal nanoparticles within specific plant microchannels through regioselective deposition, resulting in reduced chemical usage and an accelerated process. Moreover, this method effectively minimizes the required catalyst dosage. In this process, the plant monolith's aligned, narrow, and accessible channels provided a higher contact area, shorter diffusion path, and abundant oxygen-containing functional groups for rapid transformation of metal salt precursors into catalytic metal nanoparticles with excellent dispersion. The inside-out strategy can be extended to various plant-based monoliths and diverse metal/metal oxide/MOF materials within the plant monolith, thereby offering a facile, time- and cost-effective universal approach for skillfully designing plant-based flow microreactors for a wide range of applications.

The interplay of shape and catalyst distribution in the yield of compressible flow microreactors.

We develop a semi-analytical model for transport in structured catalytic microreactors, where both reactant and product are compressible fluids. Using lubrication and Fick-Jacobs approximations, we reduce the three-dimensional governing equations to an effective one-dimensional set of equations. Our model captures the effect of compressibility, corrugations in the shape of the reactor, and an inhomogeneous catalytic coating of the reactor walls. We show that in the weakly compressible limit (e.g., liquid-phase reactors), the distribution of catalyst does not influence the reactor yield, which we verify experimentally. Beyond this limit, we show that introducing inhomogeneities in the catalytic coating and corrugations to the reactor walls can improve the yield.

Nest-shaped hollow-encapsulated Pd catalyst enhances the catalytic performance of hydrogen peroxide directly synthesizing from hydrogen and oxygen

A well-defined structural morphology can significantly construct a special catalytic micro-reaction environment to enhance the catalytic performance of Pd catalyst in the direct synthesis of hydrogen peroxide from hydrogen and oxygen (DSHP). In this study, SiO2 was used as a rigid template, PdCl2 as the Pd precursor, and dopamine hydrochloride (DA) as the carbon and nitrogen source to synthesize a nest-shaped hollow-encapsulated Pd catalyst named PdMulti@ONHCS. This catalyst was successfully constructed via high-temperature pyrolysis of poly dimethyl diallyl ammonium chloride (PDDA), which generated a blasting effect crucial for this formation. Characterization analysis, catalytic performance evaluation experiment, and molecular dynamics simulation were conducted to explore the structure-performance relationship of PdMulti@ONHCS catalyst in DSHP. Both experimental and simulation results consistently showed that the nest-shaped hollow structure of PdMulti@ONHCS catalyst created a distinctive catalytic microreactor environment with a spatial mass transfer constraint, which was not only conducive to adsorption and enrichment of H2 and O2 at Pd active sites to produce H2O2. In addition, the generated H2O2 can be desorbed from Pd active sites in time and rapidly diffused into the reaction solution, effectively inhibiting the dissociation of species containing OO bonds on the Pd surface, resulting in severe hydrogenation and decomposition side reactions, and improving H2O2 productivity and selectivity.

Resistive Heating Catalytic Micro-Reactor for Process Intensified Fuel Reforming to Hydrogen

Abstract Process intensification of fuel reforming using micro-reactors has become crucial for feed flexibility in H2 production for fuel cells. In the literature on microreactors, energy supply for these endothermic reactions has faced limitations, relying on external heating, or autothermal operation. This paper explores a novel approach using a thin-film catalytic heater to develop micro-reactors. The study focuses on dry methane reforming in a simplified micro-reactor where thermal energy is supplied through electric resistive heating of a thin carbon sheet with a catalyst applied to its surface. The thin catalytic heated layer inside the reactor minimizes energy losses and the reactor footprint. Power input was varied from 90-225 W to understand its impact on the reactor temperature, CH4 conversion, H2 and CO yields. Fast thermal response times were achieved using the carbon paper as thin film for heating. Ni/MgO impregnated onto carbon paper was utilized as the catalytic heating element which resulted in CH4 conversions greater than 60% at temperature above750 K. Influence of operating conditions such as the input molar ratio of CO2/CH4, and gas hourly space velocity (GHSV) were also investigated to understand the scope of the catalyst in this setup. High GHSVs (592,885 and 948,617 mL/(hr.gcatalyst)) were tested to understand the throughput achievable using this setup. This approach demonstrates improved scope and feasibility for further intensification compared to conventionally heated microreactors. The research paves the way for efficient and compact micro-reactors for fuel reforming processes.

ZSM-5 monolithic microreactors with hierarchical porosity: Maximizing selective production of para-xylene

ZSM-5 monoliths with Si/Al ∼40 were achieved by steam assisted conversion of micro-/macroporous silica-alumina monoliths synthesized by an optimized combination of spinodal decomposition and sol-gel process. ZSM-5 monoliths exhibit a homogeneous and interconnected network of macropores of ∼30 μm diameter, with a macropore volume of ∼1 mL g−1 and a micropore volume of 0.16 mL g−1, as waited for pure ZSM-5. The skeleton of ZSM-5 monoliths featured a 3D aggregation of spherical particles of 6 μm in diameter. The latter were composed by a stacking of thin plate-like shaped crystallites. The catalytic properties of the ZSM-5 monoliths were assessed through their use as catalytic microreactor in the continuous flow alkylation of toluene with methanol. An outstanding for para-xylene selectivity of 81 % was achieved possibly ascribable due to the maximization of pore openings of sinusoidal channels as a result of the plate-like morphology of the ZSM-5 crystallites.

Four-channel catalytic micro-reactor based on alumina hollow fiber membrane for efficient catalytic oxidation of CO

The traditional automotive catalytic converter using commercial ceramic honeycomb carriers has many problems such as high back pressure, low engine efficiency, and high usage of precious metals. This study proposes a four-channel catalytic micro-reactor based on alumina hollow fiber membrane, which uses phase inversion method for structural molding and regulation. Due to the advantages of its carrier, it can achieve lower ignition temperature under low noble metal loading. With Pd/CeO2 at a loading rate of 2.3% (mass), the result showed that the reaction ignition temperature is even less than 160 °C, which is more than 90 °C lower than the data of commercial ceramic substrates under similar catalyst loading and airspeed conditions. The technology in turn significantly reduces the energy consumption of the reaction. And stability tests were conducted under constant conditions for 1000 hours, which proved that this catalytic converter has high catalytic efficiency and stability, providing prospects for the design of innovative catalytic converters in the future.

Enhanced light olefin production from CO2 over potassium promoted Fe–Co bimetallic ZrO2 supported catalysts

Over 1300 tons of carbon dioxide (CO2) is emitted into the earth's atmosphere every second, threatening to breach the limiting global temperature increase of 1.5 °C set under the Paris Agreement. It is considered as sustainable feedstock that ensures season-wide availability for producing oxygenates and olefins. Likewise, CO2 hydrogenation to lower olefins was performed using bimetallic Fe-Co catalysts, processed in situ in a fixed-bed catalytic microreactor at 280–380 °C and a pressure of 0.5–3 MPa. A MOF framework (UIO-66) was used to fabricate ZrO2 NPs. In addition, a series of potassium-promoted Fe-Co bimetallic catalysts over the ZrO2 NPs were prepared, characterised and studied for the hydrogenation of carbon dioxide to light olefins. With increasing K content, the selectivity of C2-C4 increased under all operating conditions. The spent catalyst exhibits the bimodal size distribution of Fe3C, Fe2O3 and Fe° after a modified Fischer-Tropsch synthesis (M−FTS) reaction. The XANES data shows that the energy of the Fe K-edge and the Zr K-edge are shifted in a positive direction compared to the respective foil, indicating the presence of oxides in the fresh catalyst. Under the optimised reaction conditions, the H2-pretreated K promoted Fe-Co catalyst (K5Co3Fe10/ZrO2) showed remarkably low methanation with an olefin (C2-C4) selectivity of 38 %. In addition, the catalyst exhibits excellent stability and activity, providing nearly constant CO2 conversion and selectivity of (C2−C4=) lower olefins, CO and paraffin over the 100 h time-on-stream.

Efficient Oxidative Decomposition of Jet-Fuel exo-Tetrahydrodicyclopentadiene (JP-10) by Aluminum Nanoparticles in a Catalytic Microreactor: An Online Vacuum Ultraviolet Photoionization Study.

The oxidation of gas-phase exo-tetrahydrodicyclopentadiene (JP-10, C10H16) over aluminum nanoparticles (AlNP) has been explored between a temperature range of 300 and 1250 K with a novel chemical microreactor. The results are compared with those obtained from chemical microreactor studies of helium-seeded JP-10 and of helium-oxygen-seeded JP-10 without AlNP to gauge the effects of molecular oxygen and AlNP, respectively. Vacuum ultraviolet (VUV) photoionization mass spectrometry reveals that oxidative decomposition of JP-10 in the presence of AlNP is lowered by 350 and 200 K with and without AlNP, respectively, in comparison with pyrolysis of the fuel. Overall, 63 nascent gas-phase products are identified through photoionization efficiency (PIE) curves; these can be categorized as oxygenated molecules and their radicals as well as closed-shell hydrocarbons along with hydrocarbon radicals. Quantitative branching ratios of the products reveal diminishing yields of oxidized species and enhanced branching ratios of hydrocarbon species with the increase in temperature. While in the low-temperature regime (300-1000 K), AlNP solely acts as an efficient heat transfer medium, in the higher-temperature regime (1000-1250 K), chemical reactivity is triggered, facilitating the primary decomposition of the parent JP-10 molecule. This enhanced reactivity of AlNP could plausibly be linked to the exposed reactive surface of the aluminum (Al) core generated upon the rupture of the alumina shell material above the melting point of the metal (Al).

Multi-objective structure optimization and performance analysis of catalytic micro-reactor channel designed by an improved topology optimization model

Previous micro-reactor channel studies mainly focus on the limited design space or structure layout, rarely exploits design forms in which the procedural topology structure evolves freely. Therefore, a multi-objective topology optimization model are proposed for the inverse free evolution of micro-reactor channels, which can synergistically balance the effects among three objectives of reaction rate, flow loss and heat transfer to achieve optimal comprehensive performance. The topology optimization problem is formulated based on the material density-based design variable. The fluid dynamics response of design variables at each optimization iteration is updated by solving multi-physics governing equations, objective functions and variable constraints. Adjoint-based sensitivity analysis and GCMMA algorithm are used to obtain the gradient information of objective functions and update design variables, respectively. Additionally, the strict volume constraints and proposed pseudo-design-domain concept are introduced into the multi-objective function. In numerical examples, the influence of different Re conditions and different multi-objective weight-ratios on optimal designs is investigated, and their regular evolution mechanisms and the trade-off between performance optimization and structure evolution are analyzed. Then, the optimization principles for topology structure and performance parameters under the control of multi-objective functions are revealed. Finally, the comprehensive performance of micro-reactors under topology optimization method is compared with that of traditional micro-reactors to demonstrate the effectiveness of the improved method and reveal the physical mechanisms of multi-objective performance enhancement. The comparison results show that topology optimization designs can achieve 86.1% growth in reaction rate and 47.1% reduction in flow loss, and comprehensive performance coefficients have also been significantly optimized.

Laccase-based catalytic microreactor for BPA biotransformation

A laccase-based catalytic reactor was developed into a polydimethylsiloxane (PDMS) microfluidic device, allowing the degradation of different concentrations of the emergent pollutant, Bisphenol-A (BPA), at a rate similar to free enzyme. Among the immobilizing agents used, 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) was capable of immobilizing a more significant amount of the laccase enzyme in comparison to glutaraldehyde (GA), and the passive method (2989, 1537, and 1905 U/mL, respectively). The immobilized enzyme inside the microfluidic device could degrade 55 ppm of BPA at a reaction rate of 0.5309 U/mL*min with a contaminant initial concentration of 100 ppm at room temperature. In conclusion, the design of a microfluidic device and the immobilization of the laccase enzyme successfully allowed a high capacity of BPA degradation.

A MOF nanoparticle@carbon aerogel integrated photothermal catalytic microreactor for CO2 utilization.

A practical carbon dioxide (CO2) conversion and utilization system shows great potential for ameliorating the greenhouse effect. Herein, an integrated carbon aerogel-based photothermal catalysis microreactor with photothermal conversion, enhanced mass transfer adsorption and a thermal catalytic reactor is designed. As a solar-powered CO2 utilization module, this microreactor can conveniently convert CO2 into economically valuable products without elaborate equipment and operation processes.

Construction of Marigold-like Poly(vinyl alcohol) Microspheres for Catalytic Microreactors.

It has long been pursued to develop polymer microspheres with various special morphologies and structures for better results in applications such as catalysis, drug delivery, and bioscaffolds. However, it remains a challenge to develop a facile method to produce poly(vinyl alcohol) (PVA) microspheres with special morphologies. Herein, a micron-sized marigold-like poly(vinyl alcohol) (CE-PVATPA) microsphere was engineered and fabricated by a feasible strategy, that is, emulsification-cross-linking, freeze-drying, and secondary acetal reaction steps. The morphological evolution of microspheres was systematically investigated under different conditions, and the procedure of constructing PVA microspheres with stabilizing marigold-like structures was proposed. More importantly, a specially structured PVA microsphere microreactor synergistically loading palladium metal nanoparticles (CE-PVATPA@Pd) for the heterogeneous catalyst 4-nitrophenol (4-NP) could be further demonstrated, which indicated high catalytic activity and excellent recyclability. The resultant stabilized fabricating method is promising to provide valuable guidance for the design and fabrication of a high-performance PVA microsphere microreactor.

Self-assembly immobilization of a universal catalytic microreactor for glycosyltransferases

Hyaluronic acid (HA) and chondroitin sulfate (CS) are polydisperse glycosaminoglycans (GAGs),which have important applications as health care products and drugs in skin beauty and arthritis prevention. Enzymatic synthesis is a significant strategy to obtain oligosaccharides and polysaccharides with uniform chain length and well-defined structure. However, the limitations of glycosyltransferase, such as low expression, poor stability, and difficulty in reuse, greatly restrict its application in large-scale commercial production. In this study, we constructed the expression system for hyaluronic acid synthase PmHAS and chondroitin synthase KfoC to obtain the enzyme with high expression level and good water solubility. Subsequently, we screened and optimized several highly biocompatible metal-organic frameworks (MOFs) to immobilize two glycosyltransferases efficiently. The resulting enzyme@MOF composite can catalyze the synthesis of hyaluronic acid and chondroitin oligosaccharides/polysaccharides in quantitative yield. Meanwhile, the supramolecular interactions between enzyme and hydrophilic MOFs confer satisfactory stability, durability, and reusability on immobilized PmHAS and KfoC.

Kinetic model of CO2 methanation in a microreactor under Power-to-Gas conditions

The kinetics of CO2 methanation using a 12%Ni/γ-Al2O3 catalyst was modeled in a catalytic microreactor, considering the three-dimensional momentum, heat and species continuity balances in stationary state. The microreactor consisted of 80 microchannels with dimensions 0.45 × 0.15 × 50 mm3 in each one with an average 0.04 mm catalytic thickness. Several experimental tests were carried out at various conditions of flow rate (110, 130 and 140 mL/min), temperature (275, 300, 325 and 350 °C) and reactants partial pressure. Kinetic parameters were modeled and fitted using COMSOL Multiphysics 6.0 and Matlab 2021 R. Using the corrected Akaike information criterion (AICc), it was determined that a power kinetic model with a low kinetic exponent, 0.12 ≤ n ≤ 0.18, is adequate to represent a wide range of experimental CO2 conversion and CH4 yield (up to 86%) data. An activation energy around 83–85 kJ/mol was estimated, as well as a correlation between the different parameters of the power rate law. The temperature raise significantly increases the CO2 conversion and methane yield under the operational conditions used, due to the distance from thermodynamic equilibrium. It was numerically verified that under the experimental conditions the microchannels operate isothermally. Using this model, it is possible to evaluate the effect of operational variables (temperature, volumetric flow and H2/CO2 ratio) and reactor design (microchannel surface/volume ratio) on methane production, proving potential application in catalytic efficiency studies for Power-to-Gas applications. It is clear that processes intensification is useful to achieve higher CO2 conversions fostering sustainable development of closed-carbon production cycles.

On the effects of surface waviness upon catalytic steam reforming of methane in micro-structured reactors - a computational study

The effects of wavy channels upon steam methane reforming in catalytic micro-structured reactors, using Nickle as the catalyst, are investigated numerically. Laminar, three-dimensional models of reacting flows, with heterogeneous chemistry, are developed and applied to micro-structured reactors with different wave patterns on their internal walls. It is observed that introduction of surface waves on the walls of reactor, can significantly alter production and consumption of H2 and CH4. This is shown to be due to large fluctuations in convective mass and heat transfer, induced by the surface waviness. In particular, it is shown that separation and reattachment of concentration and thermal boundary layers and the subsequent modifications in Sherwood and Nusselt number can significantly affect the catalytic processes over the walls of reactor. A major local intensification of catalytic processes is observed where Sherwood and Nusselt number are maximised. Similarly, the catalytic process becomes highly inefficient in places with minimal Sherwood (and Nusselt) number. The analyses further reveal that a strategic discrete coating of wavy walls with the catalyst can substantially improve the performance of microstructure. For example, by coating only 25% of the surface area of wavy walls, CH4 conversion rate and selectivity per coated surface area increase by 459% and 308% compared to those of an equivalent fully coated straight channel. This implies the possibility of developing highly efficient and cost-effective catalytic micro-reactors for production of hydrogen from methane.

Ultrafine Pd Nanoparticles Encapsulated in Mesoporous TiO2 Region Selectively Confined in Bamboo Microchannels: An Ultrastable Continuous‐Flow Catalytic Hydrogenation Microreactor

Plant‐based flow microreactors with natural channel structures, renewable properties, and environmental friendliness have increasingly gained popularity in heterogeneous catalysis. However, firmly immobilizing the catalysts simultaneously with ease and adaptability, maintaining great effectivity and long‐term stability, is still a fundamental challenge. Herein, a highly efficient and ultrastable bamboo‐based catalytic microreactor (CMR) containing mesoporous TiO2 (M‐TiO2)‐encapsulating ultrafine Pd nanoparticles (NPs) is constructed for the continuous‐flow hydrogenation of nitroaromatics. The fabrication of the Pd‐TiO2 catalysts in required bamboo microchannels (Pd‐TiO2/B CMR) mainly involves a two‐step region‐selective synthetic strategy with ultra‐low chemical usage, fast preparation, and low catalyst loading (0.007 wt%). The M‐TiO2 films: 1) provide abundant oxygen vacancies and enough open cavities to facilitate the growth of Pd NPs; 2) improve Pd dispersion and reduce particle size; 3) allow diffusion of reactants, and 4) induce strong metal‐support interactions for enhanced catalytic activity and stability. The optimized Pd‐TiO2/B CMR demonstrates high efficiency (>97%) and excellent stability (1,000 h) for the continuous‐flow hydrogenation of nitroaniline, even under intermittent operation (12 h on/12 h off for five cycles) or in a real aqueous matrix (>200 h), making it a promising candidate for Pd‐catalyzed hydrogenation.

Catalytic Bioswitch of Platinum Nanozymes: Mechanistic Insights of Reactive Oxygen Species Scavenging in the Neurovascular Unit.

Oxidative stress is known to be the cause of several neurovascular diseases, including neurodegenerative disorders, since the increase of reactive oxygen species (ROS) levels can lead to cellular damage, blood-brain barrier leaking, and inflammatory pathways. Herein, we demonstrate the therapeutic potential of 5 nm platinum nanoparticles (PtNPs) to effectively scavenge ROS in different cellular models of the neurovascular unit. We investigated the mechanism underlying the PtNP biological activities, analyzing the influence of the evolving biological environment during particle trafficking and disclosing a key role of the protein corona, which elicited an effective switch-off of the PtNP catalytic properties, promoting their selective in situ activity. Upon cellular internalization, the lysosomal environment switches on and boosts the enzyme-like activity of the PtNPs, acting as an intracellular "catalytic microreactor" exerting strong antioxidant functionalities. Significant ROS scavenging was observed in the neurovascular cellular models, with an interesting protective mechanism of the Pt-nanozymes along lysosomal-mitochondrial axes.

Protocells and Prebiotic Systems

The de novo synthesis and self-assembly of molecules to establish the framework of living systems is a key target in the field of systems chemistry. The construction of synthetic cellular systems from scratch is one important such route to achieve this goal. This Special Collection on Protocells and Prebiotic Systems, guest edited by Dora Tang and Avinash J. Patil, showcases some of the most exciting work done in this field today. (D.Tang photograph copyright MPI-CBG). The de novo synthesis of molecules and their self-assembly to establish the framework of living systems is a key goal of systems chemistry. One route to achieving this is by building synthetic cellular systems from scratch which provides a gateway to understand and control emergence that arises from an integration of functional molecules and biological nanostructures at various length scales. Progress in this area can have significant impact for unravelling the origins of life, synthetic biology and future biomedical applications whilst providing fundamental insights into the mechanisms of biological systems. This Special Collection on Protocells and Prebiotic Systems brings together new and exciting work that is taking place in this field and demonstrates the extraordinary breadth of contributions required to make progress in this area: From prebiotic chemistry, to a survey of the molecular parts which can be used to design and build programmable cell-like compartments, engineer catalytic microreactors or create higher ordered architectures, to the emergence of adaptable systems where chemical environments can tune the physicochemical properties of soft materials. Furthermore, the capability to assimilate these properties to mimic fundamental biological processes such as chemical signaling; motility; energy transduction or cell growth and division are ever increasing. Whilst these examples are crucial for establishing minimal living systems, there are exciting prospects to exploit synthetic-cell-like compartments in wide-ranging applications including biomimetic materials; novel stimuli-responsive delivery platforms; biocatalysis; environmental remediation; tissue engineering; regenerative medicine; living materials and in adaptive integration to biological cells. The opinions expressed in this publication are the view of the author(s) and do not necessarily reflect the opinions or views of ChemSystemsChem, the Publisher, Chemistry Europe, or the affiliated editors. Dora Tang is currently a research group leader at the MPI-CBG, Dresden (Germany). Her multidisciplinary lab reimagines and translates the physical phenemona which drive out of equilibrium processes in cells to novel, robust and dynamic synthetic cellular systems. The minimal systems address questions in origin of life and modern biology. (Photograph copyright MPI-CBG). Avinash J. Patil is a faculty and group leader at the Centre for Organized Matter Chemistry, School of Chemistry, University of Bristol (UK). His research interests cover the design and construction of artificial cells, smart microreactors, and functional hybrid nanomaterials by combining various aspects of biology, materials chemistry, and micro/nanofabrication techniques.

Facile fabrication of rGO/PPy/nZVI catalytic microreactor for ultrafast removal of p-nitrophenol from water

The application of powdered nanoscale zero-valent iron (nZVI) in conventional reactors for water treatment is limited by insufficient mass-transfer and difficult post-separation of catalysts. Herein, a novel microreactor was constructed by anchoring nZVI on the reduced graphene oxide/polypyrrole nanocomposite (rGO/PPy) substrate within the microchannel of a stainless-steel tube through two-step electrodeposition, which catalyzed the Fenton-like reaction to remove > 99% p-nitrophenol (PNP) within 50 s, outperforming traditional batch reactors. The rGO/PPy composite substrate consolidated the adhesion on steel surface, stabilized the nZVI by forming electron-transfer complex, facilitated the decomposition of H2O2 to free •OH, and promoted the redox cycle of Fe(III)/Fe(II) via the electron donating capacity of rGO/PPy. Besides, the significant convection and highly-effective mass transfer within the microreactor also contributed to the ultrafast PNP removal. With acceptable durability, easy re-generation, and scalability, the rGO/PPy/nZVI microreactor is promising for the ultrafast removal of pollutants from water.

Rapid Screening of Kinetic Models for Methane Total Oxidation using an Automated Gas Phase Catalytic Microreactor Platform

AbstractAn automated flow micropacked bed catalytic reactor platform was developed to conduct pre‐planned experiments for rapid screening of kinetic models. The microreactor was fabricated using photolithography and deep reactive ion etching of a silicon wafer, with a reaction channel width and depth of 2 mm and 420 μm respectively. It was packed with ca. 10 mg of 5 wt. % Pd/Al2O3 catalyst to perform methane combustion, which was the selected reaction to test the developed platform. The experimental system was monitored and controlled by LabVIEW to which Python scripts for online design of experiments and data analysis were integrated. Within each experimental campaign, the platform automatically adjusted the experimental conditions, and the analysis of the product stream was conducted by online gas chromatography. The experimental platform demonstrated the capability of identifying the most probable kinetic models amidst potential models within two days.