The hybrid nanofluid is the modified class of nanomaterials with impressive thermal impact and preserves significant applications in extrusion systems, thermal management systems, engineering processes, cooling and heating materials and many more. The aim of this research is to communicate the thermal enhancement of water (H2O) and sodium alginate (C6H9NaO7) base fluids with interaction of hybrid nanofluids. The Casson fluid model is used to endorse the properties of such base liquids. The titanium dioxide and silver nanoparticles incorporate the thermal impact of hybrid nanofluid properties. The fractional simulations are performed by using the Caputo–Fabrizio (CF) time-fractional derivatives. The integration of problem is computed via Laplace technique. It is observed that the velocity profile enhanced the Grashof number. The increasing observations for Nusselt number and wall shear force due to fractional parameters are obtained.