For the first time, the use of the V&V concept for the diagnosis of economic security of agricultural enterprises was proposed. This study creates regulatory models for enterprises to make the best decisions in the network of values, when the goal is an efficient and structurally reliable cooperation. The models use theoretical game concepts for multilateral decision making, which involves both cooperation and competition. The purpose of the article was to identify the innovative component of the polystructural process of forming and diagnosing economic security of the enterprise. From a conceptual point of view, it is useful to distinguish between the analysis and diagnostics of the system of economic security of an individual enterprise, from the analysis of economic security of a set of enterprises with clear group characteristics or models. Each individual enterprise or set of enterprises has its own peculiarities that arise as a result of changes in resources and circumstances in the context of local institutions and policies. They turn into productive activities, as well as enterprise consumption and decision-making activities. In this analysis, the system of economic security of a set of enterprises is defined as a combination of small and large enterprises, which, like a group, have similar patterns of life and consumption, as well as constraints and opportunities, and for which such development strategies and interventions would be appropriate. Often such systems have similar agroecological and market conditions. Enterprises usually make their decisions to maximize profits. Profit is the result of incoming and outgoing cash flows, which, on the one hand, depend on the success of the market, and, for example, on operating costs and capital costs, on the other. Consequently, future cash flows determine the level of success, as long as the cost of time is recorded. However, an accurate estimate of future cash flows at the time of the decision is usually unrealistic. Uncertainty, for example, the development of the market, the decisions of competitors, as well as future costs, give rise to high uncertainty in future cash flows.