Case Of Simple Bone Cyst Research Articles

E-cadherin expression and its clinical significance in 41 cases of spinal plasma cell myeloma

Objective To investigate the expression level of E-cadherin in spinal plasma cell myeloma and its relationship with the clinicopathological indexes of spinal plasma cell myeloma. Methods The expression of E-cadherin was detected in 41 cases of spinal plasma cell myeloma and 14 cases of simple bone cysts by using S-P (streptavidin-perosidase) immunohistochemical staining. The relationship between E-cadherin expression and the clinicopathologica1 features was analyzed. Results In spinal plasma cell myelomas, the positive expression rate of E-cadherin (46.34%) was higher than that in simple bone cyst tissues (all negative) ( P<0.01). And the expression of E-cadherin had no obvious relationship with patients' age, gender, clinical classification or M-component ( P>0.05), but had relationship with the classification of light chain. The expression rate in lambda chain subgroup was lower than that in the others ( P<0.05). We also found the E-cadherin negative patients had a higher overall survival rate than those who had strong E-cadherin expression ( P<0.05). Conclusion E-cadherin expressed higher in spinal plasma cell myelomas than in simple bone cyst tissues and its expression had relationship with the light chain classification in spinal plasma cell myeloma. The patients with no stain of E-cadherin may have a poor prognosis. Detecting the type of light chain associated with expression of E-cadherin might be helpful in evaluating the outcome of spinal PCM patients.

A case of simple bone cyst of the mandible induced infection after tooth extraction

A case of simple bone cyst of the mandible induced infection after tooth extraction

Cisto ósseo simples em pacientes sob tratamento ortodôntico: relato de dois casos

INTRODUÇÃO: o cisto ósseo simples (cisto ósseo traumático, cisto ósseo hemorrágico, cisto ósseo solitário) é uma lesão não-neoplásica que representa aproximadamente 1% de todos os cistos maxilares, acometendo as regiões de corpo e sínfise de mandíbula com maior freqüência. Trata-se de uma cavidade intra-óssea delimitada por fina camada de tecido conjuntivo frouxo, sem revestimento epitelial. É uma lesão assintomática comumente identificada em exames radiográficos de rotina, apresentando imagem radiolúcida unilocular bem definida. Sua etiopatogênese não está bem esclarecida, mas acredita-se que o trauma local seja um fator relacionado ao seu desenvolvimento. OBJETIVO: este trabalho relata dois casos de cisto ósseo simples descobertos em exames radiográficos de rotina de pacientes que estavam sob tratamento ortodôntico. RELATO DOS CASOS E DISCUSSÃO: em ambos os casos a hipótese diagnóstica foi confirmada através de biópsia incisional e exame histopatológico. O tratamento escolhido foi a curetagem óssea, radiografias panorâmicas de controle pós-operatório mostraram reparo ósseo no local. Nestes casos, discute-se se há relação do trauma associado ao tratamento ortodôntico com o surgimento do cisto ósseo simples, ou se representa apenas um achado radiográfico, que é mais freqüente nestes pacientes devido ao maior controle radiográfico a que são submetidos.

A Case of Simple Bone Cyst Located in the Pedicle of Lumbar Spine

A Case of Simple Bone Cyst Located in the Pedicle of Lumbar Spine

増大傾向を観察しえた単純性骨嚢胞の１例

A case of simple bone cyst (SBC) occurring in the mandibular ramus of a 16-year-old girl is reported. A series of panoramic X-ray pictures obtained over the course of 7 years 6 months showed that the cyst grew along mandibular canal. During this period, the lesion expanded 14 times its initial size. Relatively normal trabeculation was seen on panoramic X-ray film 21 months after fenestration.

Simple bone cyst of the mandibular condyle with severe osteoarthritis: report of a case

A rare case of simple bone cyst in the mandibular condyle of a 33-year-old woman is reported. The condition was difficult to diagnose because the cyst was accompanied by severe osteoarthritis. T1-weighted magnetic resonance (MR) images revealed a cystic lesion with intermediate signal intensity within the condylar head and an irregular margin with intermediate signal intensity on the superior surface of the condyle. The patient was treated by high condylectomy, discectomy and reconstruction by sagittal split ramus osteotomy. Histopathological examination showed a simple bone cyst in the condylar head and erosion of the anterior articular surface due to degenerative changes.

Oxygen Scavengers in Simple Bone Cysts

Simple bone cyst is a fluid-filled, cystic lesion that occurs in the metaphysis of the long bones of children and adolescents. The chemical characteristics of the cyst fluid of the simple bone cyst are similar to those of serum. The existence of the cyst fluid itself may be an obstacle to cyst healing, and, in part, this may be because the cyst fluid contains bone destructive factors. Oxygen-free radicals, which are cytotoxic and cause connective tissue damage, are known to be generated under ischemic conditions. Blockage to the drainage of interstitial fluid within the metaphysis has been suggested as the possible primary cause of simple bone cyst, thus causing an ischemic state in which free radicals are generated. The precise measurement of free radical levels is difficult to obtain because of their extremely short half-lives. High levels of oxygen-free radicals induce high levels of oxygen scavengers locally to protect cells from the harmful effects of the free radicals. Therefore, the activity of the oxygen scavengers, superoxide dismutase and catalase, was measured in the cyst fluid of 9 cases of simple bone cyst as an indicator of high oxygen-free radical content in the cyst. Serum from the patients with simple bone cyst and joint fluid from patients with osteoarthritis were used for comparison with the intracystic levels of oxygen scavengers. Superoxide dismutase activity was directly measured at room temperature using an electron spin resonance spin-trapping technique with 5,5'-dimethyl-1-pyrroline-N-oxide as a trapping agent.(ABSTRACT TRUNCATED AT 250 WORDS)

Atypical simple bone cyst of the mandible. A case report

An atypical case of simple bone cyst involving the ramus and condyle of the mandible in a 7-year-old boy is presented. The literature is briefly reviewed.

Simple bone cyst: Evaluation of contents with conventional radiography and computed tomography

To evaluate whether gas is present in the cavity of simple bone cysts, the clinical and histologic findings of 53 patients with simple bone cysts were examined and compared with an experimental model. The model consisted of a dry mandible with the medullary bone removed and the resulting cavity injected with water. Although an air-liquid level was observed on all radiographs for the experimental model, none was observed in the clinical cases of simple bone cysts. When the experimental cavity was completely filled with water, the density in the cavity was similar to that of the surrounding water on computed tomography, but when it was filled with air, the density was lower than that of the surrounding water. In contrast, in simple bone cysts said to contain air at surgery, the cavity contents were not consistent with the density for gas on computed tomography. These results indicate that the operative finding of air in the cavity of simple bone cysts may have been in error at least in some cases.

単純性骨嚢腫におけるフォスファターゼ値の検討 骨髄血値との比較において

The concentration of the acid and alkaline phosphatase (Acid P, Al-P) in cyst fluid, in bone marrow and in peripheral blood (serum) were evaluated in 12 cases of simple bone cysts (SBC). The highest concentration of Acid P and Al-P was observed in cyst fluid, and the concentration in bone marrow was higher than serum, except two cases of huge SBC's where the concentration of Al-P were decreased markedly in the cyst fluid. In beagle dogs, variable difference of Acid P or Al-P concentration in any bone marrows was observed in either proximal or distal extremities. The concentration of glucose, electrolytes, transaminase, etc in cyst fluid, bone marrow and serum was almost equivalent in a SBC. The etiology of SBC is reportedly the impaired evacuation of the cyst fluid. However, the cyst fluid presumably circulates with the bone marrow or the peripheral blood. Lower concentration of the phosphatase in serum is probably due to diffusion from higher concentration in bone marrow. However, the high concentration of the phosphatase in cyst fluid is presumably the release of Acid P by osteoclasts, or Al-P by osteoblasts. Therefore, when the activity of osteoclasts around the cyst is overwhelming, SBC may enlarge, or when the activity of osteoblasts around the cyst is overwhelming, SBC may subside.

下顎骨の両側に発現した単純性骨嚢胞の１例 その成因と文献的考察

A review of the literatures shows that simple bone cysts of the jaw can no longer be considered rare.The clinical and radiographic appearances are mostly rather typical, but some cases have a great variation. The great majority of these lesions have been described as occurring singly in the mandible, with its bilateral occurrences being extremely rare.We reported an unusual case of simple bone cyst occurring bilaterally in the mandible of a 15-year-old girl.According to a review of the literatures 16 cases of bilateral or multiple lesions in the jaw have been reported. A discussion of the theories of origin and treatment was included.

多房性Ｘ線透過像を呈した単純性骨嚢胞の１例： その成因と発生過程に関する考察

A case of simple bone cyst in a 11 year old girl is presented. Radiographically, there was a well defined multiocular radiolucency, which was extended from TI apical region to the mesial region of 8 1 toothgerm.Really, the lesion had multiocular structure accompanying multiple lesions. Although the etiology of simple bone cyst is unknown, bleeding from the surroundings of A. alveolaris inferior at infancy was suggested as a cause of this disease.

Simple bone cyst of the mandibular condyle

Most cases of simple bone cyst of the jaw are located in the body or symphysis of the mandible. Several cases have been reported in the ramus of the mandible, one of which intruded into the condyle. Only one previous case has been reported of a simple bone cyst confined to the condyle. The following is the second reported case of a simple bone cyst of the mandibular condyle

Three Cases of Simple Bone Cyst in the Mandibular Symphysis Area

Three Cases of Simple Bone Cyst in the Mandibular Symphysis Area

Simple bone cyst of the mandible

Three cases of simple bone cyst occurring in young adults are presented. The lesions were mostly asymptomatic and healed rapidly following simple curettage. The cavities were mostly empty, without a lining membrane.

Cementum-like Bone Production in Solitary Bone Cysts (So-called ???Cementoma??? of Long Bones) Report of Three Cases. Electron Microscopic Observations Supporting a Synovial Origin to the Simple Bone Cyst

Three cases of simple bone cysts (S.B.C) in association with cementum-like bone production are reported. Analysis of our cases and the 2 previously reported in the literature as so-called cementomas has led us to conclude that the "cementoma" of long bone is not a distinct entity, but merely, a form of S.B.C. associated with a peculiar, poorly cellular form of bone which mimics tooth cementum by light microscopy only. Electron microscopic studies of this substance demonstrate collagen fibers and numerous matrix vesicles which form the initial sites of calcification. Matrix vesicles are a product of osteoblastic activity and are never found in the cementum of the tooth or oral cementum producing tumors. We also report the first ultramiscroscopic observations on the wall of the simple bone cyst and its lining. Two cell types constitute the lining, having features identical to those described for type A and type B synovial cells. Because of this new observation, we believe, the most reasonable explanation for the simple bone cyst is that it represents a congenital "rest" of synovial tissue displaced into the thin, cortical metaphyseal region of bones at the synovial-capsularbone reflection. Its benign nature and slow growth would explain its discovery in early childhood and the marked preponderance of its proximal humerofemoral location dependent upon the fact that these 2 bones have the largest area of capsular to metaphyseal bone reflection.

The xeroradiographic appearance of simple bone cyst of the mandible

X eroradiography (derived from the Greek word xeros, meaning “dry”), is an electrostatic system of image recording which was developed by Chester Carlson in 1938 and is the basis of many commercial document copying machines. The first dental application of xeroradiography was reported by Hills and associates,3 in 1955, and during the past 3 or 4 years a number of articles have appeared in the dental literature on the use of this technique, especially in the disciplines of orthodontics and oral surgery.2-’ These reports indicated that xeroradiography can produce images of the head and neck region with an excellent contrast not possible with standard x-ray techniques. Thus, it would seem that xeroradiography will be used more and more frequently in the future, especially in the field of cephalometrics. A review of the literature, however, reveals a shortage of information concerning the xeroradiographic features of pathologic conditions of the jaws. For this reason, we present the comparative results of conventional roentgenographic and xeroradiographic techniques in the detection and diagnosis of a classic case of simple bone cyst of the mandible.

Simple bone cyst: Report of two cases

Two cases of simple bone cyst are presented. The first is unusual because of its radiologic appearance simulating ameloblastoma and its prolonged healing time, requiring surgical intervention on several occasions. The second is presented because of the occurrence of bilateral cysts, of which there are only eight other reported cases. It is postulated that the first case might represent a single large simple bone cyst that had several chambers with tenuous connections or that it might be an example of multiple simple bone cysts in close proximity.

FIBROUS LESIONS OF BONE IN CHILDHOOD.

Twelve cases of non-osteogenic fibroma, 13 cases of simple bone cyst and 19 cases of extracranial localised fibrous dysplasia have been analysed with particular reference to the differential diagnosis of these three conditions. All the cases first presented under the age of 20 and the diagnosis was confirmed on clinical, radiological and histological grounds.