This study examined the frequency and distribution of musculoskeletal problems among Kaduna Refining and Petrochemicals Company Limited (KRPC) engineers, desk workers, security. Data for the study were gathered using a modified online version of the Nordic musculoskeletal questionnaire. The prevalence and patterns of musculoskeletal disorder (MSD) were assessed and data from a survey given to KRPC employees was analyzed using SPSS. According to the survey, there were 62.4% of MSD cases among KRPC employees overall over 12 months. The prevalence of MSD was highest for lower back (%), followed by upper back (%) and the wrist (%). Years of experience and MSD were significantly associated (P >0.05). Employees with 16 to 25 years of work experience had a very high prevalence of MSD (84.9%). The power plant and quality control (PPQ and C) departments as well as the maintenance department had the highest rates of MSD. The findings can be used by KRPC management and any other refinery to address MSD problems among its employees and to close a gap in the body of knowledge regarding how MSD affects refinery workers in general.