Case Of Lipodystrophy Research Articles

LIPODYSTROPHY IN ADULTS

Morgagni is credited with the first description of a apparently resembling lipodystrophy. The first comprehensive clinical description of the condition in the American literature was recorded, in 1885, by S. Weir Mitchell. 1 It is regrettable that in the literature only occasional mention appears of his excellent description of a case of absence of adipose matter in the upper half of the body. In the past few years cases of lipodystrophy with superimposed clinical features have been reported, and we believe that cases exhibiting many additional interesting phenomena should be placed on record so that an analysis of these protean manifestations may lead one to a true interpretation of the disease. The subject has been adequately reviewed by several writers, so that reiteration is not necessary. However, as we critically perused the cases reported to date, we were impressed with the contrast between the manifestations found in adults and

NEUROPSYCHIATRIC ASPECTS OF LIPODYSTROPHIC DISTURBANCES

Eighty-two reports of cases of lipodystrophy were reviewed. Fifteen patients were markedly self-conscious about changes in their appearance. In 17 cases the family or friends were worried about the patient's health. In eight, nervous or mental symptoms were rather marked. In 43 no abnormality of behavior was noted. There seemed to be no psychiatric symptom-complex common to lipodystrophy, aside from self-consciousness and the tendency to share in the alarm of friends and relatives. Psychiatric symptoms when present seemed on the whole to be psychoneurotic. No constant neurologic symptoms or signs were observed accompanying lipodystrophy. Although weakness is a usual symptom at one stage or another of lipodystrophy, no general symptom-complex or diseases can be considered closely related to it until more cases are available for study. Nervous symptoms in all cases resulting from self-consciousness over personal appearance are not constantly present. No conclusive evidence has been collected to support the ...