Objectives: This paper reviews the use of new surgical techniques and biomaterials for enterocoele or rectocoele prolapse surgery in our clinical practice over the past 5 years. A comparative series was carried out using either Pelvicol™ Implant, or posterior Intravaginal Slingplasty (IVS) combined with bridge or posterior repair. Methods: Between October 2000 and October 2001, 104 patients were treated with Pelvicol™ Implant (without additional IVS implants). Pelvicol™ Implant was placed in an anterior ( n=14), posterior ( n=80) or anterior and posterior ( n=10) position. The minimum follow-up period was more than 6 months, with investigations carried out every 6 months during the follow-up period. Results: The local performance of Pelvicol™ Implant was superior to that of conventional treatment. Complications with Pelvicol™ Implant were rare with few observed cases of expulsion, recurrence, shrinkage, induration, dyspareunia, or urgency-frequency syndrome. There were no reports of dyspareunia among any of the sexually active patients getting sufficient (local or systemic) estrogens. In addition, there were no reported infections. Although patients experienced a rise in temperature on the second and third day after surgery with a corresponding increase in serum levels of C-reactive protein, temperatures had normalised by days 4 and 5 post-operation, followed by normalisation of serum C-reactive protein levels. Conclusions: The migration of cells, ingrowth of tissue, vascularisation and collagen formation in and around Pelvicol™ Implant reported by other groups obviously are properties that lead to a very pleasing result after conclusion of the healing process. Long-term results have to follow this preliminary report.