Case Of Chromoblastomycosis Research Articles

Chromoblastomycosis simulating rhinosporidiosis in a patient from Ceylon.

A case of chromoblastomycosis confined to the mucous membrane of one side of the nasal septum is reported. The organism was not cultivated, but its characteristics in histological preparations were typical of those of the organisms in sections of cutaneous lesions known to be caused by Phialophora pedrosoi and related fungi. The diagnosis is considered to have been justified in spite of the great rarity of mucosal involvement in chromoblastomycosis and of the complete absence of lesions in the skin. The patient was a Sinhalese student working in London. He had first noticed the lesion before he left Ceylon, but the symptoms of nasal obstruction and bleeding were not sufficient to make him seek medical advice until two years later. If it is correct to assume that he contracted the infection in Ceylon his case is only the second on record in which there has been reason to suggest that Ceylon has been the geographical source of chromoblastomycosis. The lesion was excised and its site cauterized. There has been no sign of recurrence of the infection during the two years that have passed since the operation.

Chromblastomycosis treated with local infiltration of amphotericin B solution. Report of second case.

Chromoblastomycosis is a fungus disease which has been recognized in most of the tropical and semitropical countries of the world. To date 27 cases have been reported in North America, predominantly from the southern portion of the United States.1With the possible exception of those cases where wide surgical excision was curative and not disabling, attempts to find a successful therapy have not been encouraging.2The first successful treatment of a case of chromoblastomycosis by local infiltration of amphotericin B has been reported.3Fourteen months of observation after this local therapy, there was still no clinical or laboratory evidence of a recurrence in the patient. This route of administration of amphotericin B was instituted because the intravenous therapeutic blood level of 40 mcg. per milliliter necessary to inhibit the growth of the causative organism far exceeds the maximum intravenous dose tolerated by human beings.4 Because of

Indentificação de cogumelos patogênicos por meio da coloração ácido periódico -- Schiff

Os autores apresentam 6 casos de blastomicose sul americana, 2 casos de actinomicose, 1 caso de rinosporidiose, 1 de cromoblastomicose e 1 caso de criptococose, estudando os respectivos cogumelos responsáveis, pela coloração empregando o ácido periódico-Schiff. As vantagens dêste método para identificação e estudo morfológico são evidenciadas pelas microfotografias apresentadas.

Report of two cases of chromoblastomycosis in New South Wales.

Report of two cases of chromoblastomycosis in New South Wales.

Chromoblastomycosis: report of nine cases from a single area in Louisiana.

CHROMOBLASTOMYCOSIS is ordinarily regarded as an uncommon type of fungous infection anywhere in the world and as an actually rare infection in the United States. When Carrion 1 published his article on the subject in 1950, he included a critical analysis of all the cases reported up to 1947, of which he accepted 157 as verified. Of these, 43 had occurred in Cuba, 41 in Brazil, 15 in Puerto Rico, 12 in South Africa, and 9 in the United States. The remaining cases occurred in small numbers in various parts of the world with the exception of Asia. The apparent immunity of that continent now no longer exists, a case of the disease having been reported from China in 1951. 2 The first case of chromoblastomycosis in the United States occurred in Massachusetts in 1915 and was described by Medlar 3 and Lane 4 in separate publications. Since

Chromoblastomycosis (dermatitis verrucosa); report of a case.

SUMMARY A case of chromoblastomycosis, a superficial mycotic disease, is reported as having occurred in the east coast area of the North Island of New Zealand. Chromoblastomycosis affects the male more frequently than the female, usually in the age group thirty to fifty years. This case is that of a male aged seventy years, and as is usual, an exposed part of the body–the arm only– was affected. The duration of the lesion was roughly three years. The clinical and histological appearances of the lesion were in conformity with those reported by Barrack in Queensland. The organism isolated on cultures was of the genus Hormodendrum. The disease has never been reported in New Zealand previously to our knowledge. The fact that it occurred in an Oriental market gardener, domiciled for 47 years, makes it highly probable that the infection was contracted in New Zealand. It is our belief that this disease is present in New Zealand, and that it has not as yet been recognized, since the lesions may well resolve spontaneously or be destroyed by diathermy or surgery without histological examination or culture. There has been no evidence to show that the patient was engaged in work associated with heavily timbered country, although native bush is or has been within a radius of ten miles of the areas cultivated for market gardening in this case. The climatic conditions are essentially those of the temperate zones in latitude 35 to 40 degrees south.

Chromoblastomycosis; thirteenth reported case in the United States.

In 1943 Moore, Cooper, and Weiss reported two cases of chromoblastomycosis and noted that six cases of the disease contracted in the United States had been reported previously. The 9th case was reported by Binford, Hess, and Emmons and the 10th by Mundt and Moore. Lewis and his associates reported on a 67-year-old man with chromoblastomycosis of seven years' duration on the right hand. Chronic infectious granuloma developed after the hand was injured by wood splinters, and microscopic examination revealed chromoblastomycosis. Conway and Berkeley reported the case of a 44-year-old Negro man who sustained an abrasion on the side of the foot that developed into a slightly elevated tumor with purplish-black nodules. The first case report from Canada was by Berger, Beaudry, and Gaumond. The disease has been reported once each in Massachusetts, Pennsylvania, North Carolina, Georgia, Florida, Texas, and Louisiana, twice in New York, and three times in Missouri.

Chromoblastomycosis; report of first case recognized in Michigan, apparently contracted in South Carolina.

THE FIRST case of chromoblastomycosis in the United States was reported by Medlar 1 and by Lane, 2 who discussed it from different points of view. This case was found in Massachusetts. A few additional cases from North America have been added to the literature. Reports include one case by Wilson, Hulsey, and Weidman, 3 from Texas, in 1933; one by Martin, Baker, and Conant, 4 from North Carolina, in 1936; one by Moore and Mapother, 5 from Missouri, in 1940; one by Emmons, Hailey, and Hailey, 6 from Georgia, in 1941; one by Weidman and Rosenthal, 7 from Pennsylvania, in 1941; two by Moore, Cooper, and Weiss, 8 from Missouri in 1943; one by Binford, Hess, and Emmons, 9 from Georgia, in 1944, and one by Mundt and Moore, 10 from Louisiana, in 1947-1948. Weidman and Rosenthal 7 in 1941 summarized 110 cases of chromoblastomycosis from the

CHROMOBLASTOMYCOSIS IN PANAMA

The purpose of this article is to report a new case of chromoblastomycosis, diagnosed in the Hospital Santo Tomas, with what I consider to be a new clinical form of the disease. REPORT OF A CASE E. H., a white man 30 years of age and born in Corozal (Province of Los Santos), Republic of Panama, where he had lived and worked as a farmer (wearing sandals), was hospitalized for a verrucous type of dermatosis on the anteroexternal aspect of the left leg (fig. 1 A ) of two years' duration. The lesion began as a small nodule and gradually increased in size. It bled easily with minor traumatism and was slightly pruritic and not painful. On removal of the crust from the cutaneous surface which had been traumatized, there was a seropurulent exudate which had a typical odor. The verrucous nodule at the time of my examination measured 16 by

MADURA FOOT (MYCETOMA)

SOME TIME ago it was interesting to note the lack of bibliographic data on actinomycosis on the Isthmus of Panama, whereas there were various reports from Puerto Rico,1Cuba2the southern part of the United States3and Mexico,4which, like the isthmus, bound the Caribbean Sea. Also the geographic location of the isthmus, with its warm, humid climate, would appear to make it a favorable region for any type of mycotic infection. The later diagnosis in the first 2 cases of chromoblastomycosis,5when I commenced my investigations, and in the third and fourth cases (as yet unreported), observed in the last fifteen months, leads me to believe that actinomycosis can be encountered on the isthmus in any of its clinical forms, in particular, Madura foot (mycetoma), or that it has been recognized but has not been reported in the past. My study has confirmed my previously

CHROMOBLASTOMYCOSIS

<b>T</b>WO NEW cases of chromoblastomycosis are reported in this paper to make a total of 3 cases already diagnosed in the Isthmus of Panama and a total of 154 cases diagnosed in the whole world¹since the discovery of the disease by Pedroso and Gomez²in Brazil and the first publications by Medlar³and Lane.⁴ I am not able to tell anything about the incidence of the disease here until the medical profession has a better knowledge of its five clinical forms,⁵and of how a diagnosis may be made. Chromoblastomycosis may be diagnosed by the observation of sclerotic cells on microscopic examination of the material obtained by scraping the lesions, by the culture of the scabs in Sabouraud's medium and the subsequent study of the fungi⁶or by the agglutination reaction.⁷However, it was a great surprise to me,

CHROMOBLASTOMYCOSIS

At this time, when there is renewed interest in the study of tropical diseases, it is considered worth while to report another case of chromoblastomycosis occurring in a person who had never been outside the continental United States. It is furthermore considered of value to emphasize the fact that a considerable distance (Atlanta, Ga., to New Orleans) between the physician treating the patient and the laboratory offered no real difficulty in making the diagnosis and culturing the causative fungus. In the mycologic section of this paper we have corrected the name of the causative fungus to conform with present knowledge of the etiologic agents of this mycosis. The generally accepted name of the disease, chromoblastomycosis, however, has been retained. The substitute term, chromomycosis, which has been proposed is somewhat shorter, but in our opinion it is unsuitable for reasons which have been discussed elsewhere. 1 Many