Case Of Skin Infection Research Articles

Selective Dorsal Rhizotomy for Spastic Cerebral Palsy: Report of 18 Cases Performed in the North of Vietnam

The purpose of this report is to describe a case series of children undergoing selective dorsal rhizotomy (SDR) for the treatment of spastic cerebral palsy in Vietnam. Also described is an international cooperation model to facilitate the development of a new, multidisciplinary team for the evaluation and treatment of these children. Details of international collaboration are described, including in-person travel and virtual interactions. All cases of children younger than 18 years undergoing SDR for treatment of spastic cerebral palsy at a single center in Hanoi, Vietnam are described, including preoperative evaluation of spasticity and gait as well as results at 6 and 12 months. Results are summarized using descriptive statistics. Since the beginning of cooperation in training and transferring SDR techniques by experts from the United States, in the period from June 2016 to December 2022, 18 SDR surgeries were performed in Hanoi. Patients' ages ranged from 2 to 14 years; 13 were male and 5 were female. Overall, approximately 60% of nerve rootlets were cut. Modified Ashworth Scale scores at 6 and 12 months after surgery in the hip, knee, and ankle joints showed improvement from preoperative values. There were 2 recorded complications: intracranial hypotension causing subdural hemorrhage and a case of skin infection at the incision site. The ongoing international cooperation between Vietnamese and American physicians has helped improve the surgical treatment of spasticity in children with cerebral palsy in Hanoi, providing children with a surgical treatment option with successful outcomes.

Sosialisasi Pencegahan dan Penanganan Infeksi Kulit Pada Santriwati Pondok Pesantren Darul Ulum Batang

Dermatitis is a skin disease caused by an inflammatory reaction in the skin due to endogenous, exogenous stimuli and other unknown causes. Endogenous stimuli come from genetic factors, gender, age, race, and history of atopy. Meanwhile, exogenous stimuli come from the type and characteristics of genes, exposure characteristics, and environmental factors. Dermatitis reactions can cause skin infections. Skin infections are a problem that often becomes a major problem in Islamic boarding school environments. The high occupancy rate in Islamic boarding schools, the simultaneous use of facilities, lack of personal and environmental hygiene, as well as the lack of knowledge of the Islamic boarding school students means that cases of skin infections in Islamic boarding schools are still relatively high. For this reason, socialization and education activities are needed for students and female students regarding how to prevent and deal with cases of skin infections with the aim of increasing students' understanding of cases of skin infections and how to prevent them.

Perioperative complications of using freezing nitrogen ethanol composite to treat bone tumors: Clinical experience from a single center.

The cryoablation efficacy of semisolid freezing nitrogen ethanol composite (FNEC) has been demonstrated. We aimed to investigate the feasibility of adjuvant FNEC-assisted cryoablation in different bone cavity types by assessing the perioperative complication rates. The medical charts of patients who received intraoperative adjuvant cryoablation using semisolid FNEC for bone tumors from December 2013 to January 2018 were reviewed. The bone cavities were categorized into three types according to liquid spill potential (type 1, able to hold liquid without limb manipulation; type 2, required extensive limb manipulation to retain liquid; type 3, unable to retain liquid). The overall complication rate and the complication rates stratified by bone cavity type were determined. Among the 76 patients, 30.3%, 57.9%, and 11.8% had type 1, 2, and 3 bone cavities, respectively. The mean follow-up time for perioperative complications was 43.5 ± 24.1 days. Five patients experienced complications, including two cases of skin damage, two cases of skin infection, and one case of fracture, yielding an overall perioperative complication rate of 6.4%. All cases of skin damage and skin infection were superficial and manageable by oral antibiotics. The patient with a pathologic fracture recovered well after being treated with open reduction and plate fixation. No neuropraxia was noted within the first few days postsurgery in any patient. The complication rates in type 1, 2, and 3 bone cavities were 13%, 4.6%, and 0%, respectively. All bone cavity types had a low incidence of perioperative complications after treatment with adjuvant FNEC-assisted cryoablation. Semisolid FNEC-assisted cryoablation is a feasible alternative to overcome the liquid spill potential in bone cavities resulting from tumor resection and intralesional curettage.

Clinical applications of skin traction technique with adjustable tension in treatment of large area skin defects

ObjectiveTo explore the clinical applications of the adjustable skin traction technique in the treatment of large area skin defects.Research designA prospective study.BackgroundThe skin is the largest organ of the human body and skin tissue exposed to external environment which makes it vulnerable to damage. There are many reasons for skin defects such as trauma, infection, burns, scars, tumors resection, inflammation, pigmented nevus, etc. Skin traction is the application of pulling force to the trunk or extremities for immobilization, fracture reduction and deformity correction. This technique accurately controls skin expansion which is safe, convenient and accelerates wound healing.MethodsA prospective study was conducted on 80 patients suffered from large area skin defects in the department of orthopedics, the first affiliated hospital of Zhengzhou University from September 2019 to January 2023. There were 40 patients in the experimental group who underwent skin traction. In contrast, 40 people in the control group underwent skin flaps or skin grafts without skin traction. The inclusion criteria include large area skin defects, normal peripheral skin & blood supply, normal vital organs, no severe coagulation dysfunction etc. Male & female with and without skin traction are 22 & 18 and 25 & 15 respectively. The skin traction device used was a hook and single rod type. The skin defect area was approximately 15 cm × 9-43 cm × 10 cm.ResultsPostoperatively, the experimental group with traction showed 2 cases of skin infection, 1 case of skin necrosis and 3 cases of inflammation recurrence. In contrast, the control group without traction showed 8 cases of skin infection, 6 cases of skin necrosis and 10 cases of inflammation recurrence. Skin infection (P = 0.04), skin necrosis (P = 0.02) and inflammatory response (P = 0.03) represented significant differences between two groups. There was also a significant difference in hospitalization costs (P = 0.001).ConclusionSkin traction has huge clinical applications including a shorter hospital stay, faster wound healing, lower hospitalization cost, high satisfaction rate, and a fair skin appearance after surgery. It is an effective method of treating skin and musculoskeletal defects.

Risk Factors of Infection in Nephrotic Syndrome

Objective: To determine the risk factors of infection in patients with nephrotic syndrome. Methods: A retrospective study was conducted on 155 patients with nephrotic syndrome under our department from January 2019 to December 2019. Among them, 43 cases had infection, and the rate of infection was 27.74%. The risk factors of infection were analyzed. Results: Among the 155 patients with nephrotic syndrome, 43 cases developed infection, including 3 cases of upper respiratory tract infection (6.98%), 33 cases of lower respiratory tract infection (76.74%), 3 cases of skin infection (6.97%), 3 cases of urinary tract infection (6.97%), and 1 case of facial nerve infection (2.32%). Compared with the group without infection, the group with infection had lower serum albumin and immunoglobulin G (IgG) levels as well as higher serum creatinine and 24-hour urinary protein levels (P < 0.05). Multivariate logistic regression analysis showed that decreased serum albumin (odds ratio [OR] = 1.14; P < 0.01) and IgG (OR = 1.1; P < 0.144) were independent risk factors for infection. Conclusion: Respiratory infection is the most common infection in nephrotic syndrome, and the decrease in serum albumin and IgG are independent risk factors for infection.

COVID-19 vaccination delivery in long-term-care using the CARD (Comfort Ask Relax Distract) system: Mixed methods study of implementation drivers

ABSTRACT Objectives CARD (comfort, ask, relax, distract) is a vaccine delivery framework that includes interventions to improve the patient’s experience. CARD has not been previously implemented in long-term care (LTC) settings. This study evaluated drivers to implementation for COVID-19 vaccinations in an LTC facility. Methods Postimplementation interpretive evaluation including qualitative interviews and quantitative surveys with eight participants. The Consolidated Framework for Implementation Research (CFIR) was used for analysis. Adverse reactions to vaccinations and CARD interventions, including local reactogenicity and systemic reactions, were abstracted from medical charts of residents. Results Eight CFIR constructs emerged. Staff perceived CARD was complex because it added steps to vaccination delivery. Motivated to meet residents’ needs, a receptive implementation climate of support among staff led to using strategies within CARD, such as administering topical anesthetics and omitting alcohol skin antisepsis prior to injections. Having an effective network like the residents council positively influenced implementation by allowing residents to voice their opinions. Facilitators to implementation included staff knowledge and beliefs and staff’s commitment to their organization, which was focused on person-centered care. Barriers included lack of available resources (inadequate staffing), insufficient communication between management and staff and lack of awareness of CARD, and external policies not aligned with CARD. Chart reviews conducted for 93 vaccinated residents corroborated perceptions of vaccination and CARD intervention safety, revealing a low rate of local and systemic adverse reactions and no cases of skin infection. Discussion We identified positive and negative implementation drivers. Future research is recommended to expand the strategies employed and involve residents more directly.

PB2278: INVESTIGATION ON THE STATUS OF INFECTION IN PATIENTS WITH MULTIPLE MYELOMA

Background: multiple myeloma; infection; clinical features; predisposing factors Aims: To preliminarily explore the clinical features, distribution of infection sites and susceptibility factors of infection in patients with multiple myeloma. Methods: he clinical data of 505 patients with multiple myeloma who were treated in our hospital from January 2015 to October 2021 were retrospectively analyzed, and they were divided into infection group and control group according to whether infection occurred. The baseline data, clinical characteristics, infection site, and blood biochemical indexes during infection were collected and analyzed. Results: Among the 505 patients, 109 patients had infection, and the infection rate was about 21.6%. Lung was the main infection site in 53 cases, followed by 6 cases of urinary system infection, 3 cases of skin infection, 2 cases of perianal infection, and 45 cases with no clear infection foci. In the distribution of pathogenic bacteria, a total of 13 gram-negative bacteria, 9 gram-positive bacteria, 13 fungi and 1 virus were detected. Males and patients with education below high school were more susceptible to infection (P<0.05). Summary/Conclusion: The incidence of infection in patients with multiple myeloma is about 21.6%. The lung is the main infection site, and gram-negative bacteria are the main infection bacteria. Male and low education are the susceptibility factors for infection.

Efficacy and Safety of Different Dosages of Decitabine in the Treatment of High-Risk Patients with Myelodysplastic Syndrome

To investigate the efficacy of high-risk myelodysplastic syndrome (MDS) patients treated by different doses of decitabine (DAC) and its safety. Thirty patients with high-risk MDS were all treated by demethylation drug DAC. According to the doses of DAC, 30 patients were divided into 10-day regimen [6 mg/(m2·d)×10 d, 15 patients] group and 5-day regimen [15 mg/(m2·d)×5 d, 15 patients] group. The efficacy and adverse events of the patients in the two groups were observed. The patients were followed up to May 2020, in the 10-day regimen group, 10 cases achieved complete remission (CR), 3 cases achieved partial remission (PR), and 2 cases were progressive disease (PD). Four cases died, including 1 case for heart failure, 2 cases for respiratory failure and 1 case for serious infection. In the 5-day regimen group, 11 cases achieved CR, 1 case achieved PR, 3 cases were PD. Five cases died, including 2 cases for heart failure and 3 for serious infection. The CR rate and ORR of the patients in the two groups were 66.67% vs 73.33%, 86.67% vs 80.00%, respectively, which showed no significant differences, and the efficacy also showed no significant difference. After treatment, the levels of WBC, NE, Hb and PLT of the patients in 10-day regimen group were higher than those in 5-day regimen. In the 10-day regimen group, there were 11 cases of pneumonia, 2 cases of bacteremia, 1 case of skin infection and 1 case of urinary tract infection. While in the 5-day regimen group, 13 cases of pneumonia, 5 cases bacteremia, 1 case of skin infection and 3 cases of urinary tract infection. There were 2 cases with mild gastrointestinal response in the 10-day regimen group, and 7 cases with obvious nausea and anorexia in the 5-day regimen group. The symptoms were relieved after the treatment of acid suppression, stomach protection and antiemetic. The liver, kidney and heart function were monitored. One case liver function damage and 2 cases cardiac insufficiency were observed in the 10-day regimen group. Seven cases regimen cardiac insufficiency and 4 cases regimen liver function damage were observed in the 5-day regimen group. 10-day regimen and 5-day regimen are equally effective, but 10-day regimen is less myelosuppressive and more safer, which can be applied in clinical.

HUBUNGAN FAKTOR RESIKO HIGIENE DENGAN KEJADIAN TINEA PEDIS

Tineapedis is not a life-threatening disease, its clinical form can last for years without significant complaints, but tineapedis can be a big problem if secondary infection (bacterial infection) has appeared with symptoms ranging from mild (rash - red rash that is sore) to more severe such as pain and fever. The itching that is caused every day because of tineapedis can also interfere with a person's activities or work so that it will reduce the quality of his life. In Indonesia, during 2000-2004, the prevalence increased by 14.4%. In Indonesia, based on data from reports in all hospitals in 2010, there were 122,076 new cases of skin infections in which tineapedis was included. Apart from wearing closed shoes for a long time, increased humidity due to sweating, mechanical rupture of the skin, level of personal hygiene, and exposure to fungi are risk factors that cause tineapedis. The purpose of this study was to analyze the relationship between hygiene risk factors and the incidence of tineapedis. This research is a type of analytic research using a literature review system by using comparisons and equations between several journals that have been selected. From the six journals that have been collected and analyzed, it can be concluded that the hygiene factor is the main risk factor for the occurrence of TineaPedis. For the journal AstritNapitupulu which contradicts other journals which states that hygiene factors do not affect the incidence of tineapedis where the effect is the use of antiseptic soap. Meanwhile, for the journal KaruniaPratama, Rustika, FadlilaMuhtadin, HeruLaksono, SantriadiHadi stated that the hygiene factor is the factor that causes tineapedis which consists of washing feet, changing socks and shoes which are the specific objectives of this thesis. The main cause of tineapedis is Trycophyton Rubrum. There is a relationship between risk factors for hygiene and the incidence of tineapedis.

Elastic stable intramedullary nailing for treatment of pediatric forearm fractures: A 15-year single centre retrospective study of 173 cases

The aim of this study was to analyze the outcomes and complications in children treated with elastic stable intramedullary nailing (ESIN) for forearm fracture. The study included 173 patients (126 men and 47 women; median age: 11 years (range: 3-17 years) treated with ESIN for forearm fracture between May 2002 and May 2018. Immobilization was not performed after the surgery. The median follow-up was 68 months (range: 3-161 months). The etiology, healing time, and complications were recorded. All patients achieved complete radiographic healing at a median of 6.8 weeks (range: 4-11 weeks). The most common injuries were sport related (n=65) and by falling from standing height (n=57), followed by injuries from bicycle riding, motorbike accidents, road traffic accidents, and fights. Fifteen (8.76%) postoperative complications were recorded: eight entry-site skin irritations, two cases of skin infection, two refractures, and one case each of nail migration, injury of ulnar nerve, and pseudoarthrosis. All complications, except cases of refractures and pseudoarthrosis, were treated conservatively, with no long-term consequences for the patients. Patients with refractures and pseudoarthrosis were reoperated, and complete function of the extremities was fully restored. ESIN for treatment of forearm fractures in children shows good functional and cosmetic results. This is a minimally invasive, cast-free, simple, and reproducible technique, with a low complication rate. Owing to these excellent objective and subjective results, surgical stabilization of the forearm fracture using ESIN is recommended in children and adolescents. Level IV, Therapeutic study.

An Epidemiological Study of Scabies by Age Groups, Regions and Gender in Diwaniya Governorate

This study included the investigation of scabies parasites, which is one of the external parasitic. It is becoming more polluted and less clean. The diagnosis from the cases reviewed to the dermatologist at Diwaniyah Teaching Hospital showed that there were many cases of skin infections with fungi and bacteria. However, the study was about scabies. The number of cases during 90 days was 120 cases after examination and diagnosis. The study showed the increase in pollution of the city center as well as the lack of ventilation, and the number of injury 29 and by 24 percent, while the lowest number was in two areas are AL- Shafaia and AL-Sudair 13 and the proportion of 10.8 percent. The number of males was 75 and 62.5%, while females were 45 and 37.5% .As for the age groups, the highest number was 41 cases in the ages of 10 years and less than 20 years and by 34% and in the age of less than 10 years were 28 and 23%. The lowest number of cases in 120 cases were 8 cases in children under 30 and over 20 years, and 6.6% .

Bisifusarium Delphinoides, an Emerging Opportunistic Pathogen in a Burn Patient with Diabetes Mellitus

An 82-year-old man with diabetes was admitted to the emergency department with a third-degree burn on his left leg. The deep swab specimen from his left leg was cultured on Sabouraud dextrose agar without cycloheximide and incubated at 25 °C for 5 days. On the basis of morphological characteristics and multigene phylogenetic analyses of the internal transcribed spacer region of ribosomal DNA and partial fragments of beta-tubulin and translation elongation factor 1-alpha, the causal agent of fungal skin infection was identified as Bisifusarium delphinoides, which was newly introduced by accommodating a Fusarium dimerum species complex. Thus, we describe here the first case of skin infection caused by B. delphinoides on a burn patient with diabetes mellitus based on morphological observation and molecular analysis.

Factors related to neonatal skin infection in community

Total 1 452 newborns were home visited within 28 d after birth during January 2016 to December 2016, and 27 cases of skin infections were found. Umbilical inflammation was more common (11 cases), followed by folliculitis (9 cases) and impetigo (7 cases). Samples were collected for bacterial culture and identification from the skin of infected newborns, the hands and nasal cavity of family baby caretakers, and household articles, including faucets, mobile phones, toilet buttons and so on. The pathogens identified were Staphylococcus aureus in 20 cases (including 2 methicillin-resistant strains) and Escherichia coli in 7 cases. The isolation of Staphylococcus aureus in household articles was significantly correlated with newborns infected with Staphylococcus aureus (χ2=678.808, P<0.01); and the isolation of Staphylococcus aureus from family baby caretakers was also significantly associated with neonatal Staphylococcus aureus infection (χ2=820.396, P<0.01). In 7 cases of Escherichia coli infection, the Escherichia coli were detected from samples of baby caretakers or household articles. The study suggests that the awareness of baby caretakers and home hygiene are important to reduce neonatal skin infections. Key words: Newborn; Skin infection; Family environment; Home care workers

A case of skin infection caused by Mycobacterium szulgai

A 7-year-old girl presented with a plaque on the left side of the face for 4 years. Skin examination revealed a well-marginated circular firm plaque measuring 6 cm × 5 cm in size on the left side of the face with purulent crusts on the surface, which was nontender to palpation. Histopathologic study showed ulceration and necrosis in some areas in the epidermis, diffuse dermal infiltration of lymphocytes, histiocytes and epithelioid cells with the presence of many neutrophilic granulocytes in some regions. Both periodic acid-Schiff (PAS) staining and acid-fast staining were negative. After 25 days of tissue culture, scotochromogenic Mycobacterium colonies grew, and colony smears showed positive acid-fast staining. The sequences of 16S rRNA and hsp65 genes of the fungal isolate showed 100% and 99% homology with those of Mycobacterium szulgai, respectively. After the treatment with rifampicin, isoniazid and ethambutol, the patient's condition was improved. Key words: Skin; Nontuberculous mycobacteria; Infection; Mycobacterium szulgai; 16S rRNA; HSP65 heat-shock proteins

Opportunistic fungi in lake water and fungal infections in associated human population in Dal Lake, Kashmir

Natural habitats of opportunistic fungal pathogens are outside of the host; therefore, it is critically important to understand their ecology and routes of transmission. In this study, we investigated the presence of human pathogenic opportunistic fungi in lake water and incidence of fungal infections in associated population in Kashmir, India. Six hundred forty water samples were taken on seasonal basis from a wide network of sampling stations of the lake for an extended period of two years for screening their occurrence. The samples were inoculated onto rose bengal agar, malt extract agar, potato dextrose agar and other specified culture media supplemented with Chloramphenicol and Streptomycin followed by incubation at 37 °C. All the samples were positive for fungi, which were later identified by sequencing the rDNA internal transcribed spacer region aided by classical morphological culture techniques and physiological profiling. The whole process led to the isolation of sixteen species of opportunistic fungal pathogens belonging to genus Aspergillus, Candida, Penicillium, Cryptococcus, Fusarium, Rhizopus and Mucor in decreasing order of prevalence. Furthermore, 20% population (n = 384) of Dal inhabitants was examined for possible fungal infections and it was observed that only 8.07% individuals were positive for fungal infections with 4.68% skin infection cases, 2.34% onychomycosis cases and 1.04% candidiasis cases. Scrapings from onychomycosis and candidiasis patients showed the presence of Aversicolor and Calbicans respectively, resembling exactly the strains isolated from the lake water. However, the skin infection was because of a dermatophyte not isolated for the lake water. Higher prevalence of infection (6.77%) was seen in people using lake water followed by a positive prevalence of 1.30% using tap water. The results of present study suggest that the lake inhabitants are at a greater risk of getting life threatening fungal diseases which may lead to various morbidities.

Value of procalcitonin measurement in the diagnosis of bacterial infections in patients with fever and flare of chronic gouty arthritis

We assessed serum procalcitonin (PCT) levels to distinguish bacterial infections from non-bacterial infections in patients with fever and flare of chronic gouty arthritis. One hundred febrile patients with chronic tophaceous gout flare-ups were collected consecutively between November 2011 and January 2014 from the Department of Rheumatology and Immunology, Sichuan Provincial People's Hospital. These patients were divided into non-infectious febrile group (68 patients) and bacterial infectious febrile group (32 patients, including 6 cases of pulmonary infection, 3 cases of infectious arthritis and 21 cases of skin infection, 2 patients died from severe infection were excluded), and 30 patients with flare of chronic gouty arthritis without fever and infection. Serum PCT, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), white blood cell (WBC) count and neutrophil ratio were determined. 57.3% (39/68) patients in the non-infectious febrile group had PCT levels ≥ 0.5 × 10³ ng/L and the ratio in the infectious febrile group was 66.7% (20/30) . No statistically significant difference was detected between them (P>0.05). 16.7% (5/30) patients had PCT levels ≥ 0.5 × 10³ ng/L in the afebrile group and both the differences between the afebrile group and the two febrile groups were significant (P<0.05). The differences of ESR, CRP, WBC count and neutrophil ratio between the two febrile groups were not statistically significant (P>0.05). In the chronic gouty arthritis patients with fever, the sensitivity and specificity of high PCT level (≥ 0.5 × 10³ ng/L) for detection of bacterial infections was 33.9% and 74.4%, the positive predictive value was 36.9% and the negative predictive value was 71.9%. The area under the curve (AUC) of PCT, CRP, ESR, WBC count and neutrophil ratio in patients with fever and chronic gouty arthritis was 0.598, 0.636, 0.612, 0.596 and 0.727, respectively. Serum PCT levels may be not a good marker for detection of bacterial infections in the patients with fever and flare of chronic gouty arthritis. Larger studies are needed to evaluate the value of PCT measurement in the patients with fever and flare of chronic gouty arthritis.

Community-acquired cutaneous ulcer in a child caused by Serratia marcescens.

Introduction:Serratia marcescens is a Gram-negative, aerobic, motile bacillus belonging to the family Enterobacteriaceae. S. marcescens has been implicated in different types of infections including urinary tract infection, septicaemia, meningitis and wound infections. Very few cases of skin infections caused by this organism have been reported in the medical literature. S. marcescens is an important nosocomial pathogen but has rarely been implicated as a cause of community-acquired soft-tissue infections.Case presentation:We present a rare case of a community-acquired spontaneous cutaneous ulcer in an immunocompetent child from a sub-Himalayan region. Infections caused by S. marcescens may be difficult to treat because of its ability to produce a β-lactamase, which confers resistance to broad-spectrum, β-lactam antibiotics.Conclusion:In our patient, the treatment was modified to ceftazidime and amikacin after sensitivity testing and the patient’s condition improved. This necessitated isolation by culture and antimicrobial susceptibility testing to ensure appropriate therapy.

What factors contribute to a higher frequency of skin infections among adults in Mauritius?

Introduction: Given the rise in the prevalence of skin infections in many countries and the lack of published data pertaining to the prevalence and awareness of skin infection in Mauritius, this survey is the first of its kind to provide data on this issue. The aim of this study is to describe the association of skin infection with various predisposing factors such as socioeconomic status, personal hygiene and level of awareness and to assess the impact of skin infections on quality of life. Material and Methods: A stratified sample of 500 adults was randomly selected for this study. Subjects were administered a questionnaire to elicit information on sociodemographic factors, awareness, family history and prevalence of skin infections. Quality of life was investigated by a validated questionnaire (DLQI). SPSS Software and Microsoft Excel were used to analyse data. Results: Among 500 participants, 166 (33%) cases of skin infections were obtained. Acne was found to be more prevalent (n=59). It was found that skin infection varies with gender and higher prevalence was observed during summer as compared to winter (p=0.017). It was noted that family history and income level were associated with an increase incidence of skin infection (p=0.000). With respect to quality of life, psychological distress was mostly affected. Conclusion: Acne was found to be more prevalent. Respondents with middle income status were mostly affected with skin infection. Those with a family history were more prone to skin infection. The Quality of Life index was found to be an efficient method in assessing the impact of skin infection on the respondents’ lives.

Infections in Children Treated With Biological Agents

Infections in Children Treated With Biological Agents

Skin infection caused by Scedosporium apiospermum in immunocompromised patients. Report of two cases

Scedosporium apiospermum is a filamentous fungus that can cause cutaneous or extracutaneous disease. A large number of cases have been published over the last decades, mainly in patients immunocompromised as a result of their disease or treatment. These kinds of infections can progress rapidly and become disseminated, leading to very serious or even fatal complications. We report two new cases of skin infection by Scedosporium apiospermum from our hospital.