Cascaded H-Bridge (CHB) multi-level inverter has become attractive in medium voltage and grid connection to improve power quality with high efficiency, and low switching losses. Voltage Oriented Control (VOC) regulates the injected power and the connection between the cascaded H-bridge inverter and the utility grid. In the modulation stage for the VOC, there are several techniques such as Space Vector Pulse Width Modulation (SVPWM), Multi-Carrier Pulse Width Modulation (MCPWM), Selective Harmonic Elimination (SHE) used to obtain gating pulses for the IGBTs switches. In this paper, a three-phase 5-level CHB inverter with a grid connection system is present and the technique of MCPWM is used. A comparative study between each method of (MCPWM) using MATLAB/Simulink environment has been done on the Total Harmonic Distortion (THD) for inverter phase voltage and current with different injected reference current values. It is found that phase current THD is less with the Phase Shift PWM (PS-PWM) technique.