Aim: The purpose of our current study is to see if there is any connection between skull fracture and extradural hematoma in head injury patients who came to the tertiary care hospital in Pakistan. Methods: From January 2020 to December 2021, this descriptive research was conducted at Chandka Medical College, Shaheed Mohtrama Benazir Bhutto Medical University Larkana. The research comprised those patients who have undergone extradural hematoma surgery during study period. Normal skull X-rays being taken, and the type and position of fractures were documented on the X-rays, CT scan, and during surgery. The frequency of skull fracture linked through extradural hematoma was studied in different ages. SPSS version 24.0 was utilized to investigate our current findings. Results: A sum of 130 individuals were operated on for extradural hematoma. In 70 cases, a linear fracture was seen, and in 18 individuals, a depressed skull fracture was seen. Another ten individuals with no radiologically evident fracture reported discovered to also have a fracture line intra-operatively. As a result, 87 (78 percent) of the participants suffered a skull fracture. Here remained no statistically important variation in occurrence of skull fracture among age ranges. Conclusion: Although there is a significant link between skull fracture and extradural hematoma, a normal X-ray does not rule out extradural hematoma. Keywords: Skull fracture, extradural hematoma, head injury, Tertiary Care Hospital, Larkana, Pakistan.