Cardiovascular Effects Of Exercise Research Articles

Effects of cardiovascular exercise on eating behaviours: Accounting for effects on stress, depression-, and anger-related emotional eating in women with obesity.

Obesity remains a medical issue of great concern. Behavioural methods attempting to induce weight loss have largely failed because of a minimal understanding of stress- and depression-associated psychosocial correlates. This study extended research into the effects of exercise on weight loss through psychological pathways to improve treatments. Women with obesity (N=108), participating in an original theory-driven cognitive-behavioural treatment within community-based health promotion centres, were evaluated over 24months. Their mean scores on anxiety, depression, and anger at baseline were significantly higher than normative data from a general sample of United States women. Three serial mediation models were specified assessing mediation of the significant exercise→dietary change relationship. These yielded two significant paths: changes in exercise→anxiety→anxiety-associated emotional eating→self-efficacy→diet, and changes in exercise→depression→depression-associated emotional eating→self-efficacy→diet; and one non-significant path: changes in exercise→anger→anger-associated emotional eating→self-efficacy→diet. In a subsequent moderated moderation model, change in eating-related self-regulation moderated the relationship between changes in anxiety and anxiety-associated emotional eating, where exercise-associated self-regulation moderated effects from eating-related self-regulation. Dietary improvement was significantly related to weight loss over 6 (β=-0.40), 12 (β=-0.42), and 24 (β=-0.33) months. Findings indicated an increased treatment focus on the completion of moderate amounts of exercise for weight loss and, following that, attention to improvements in anxiety, depression, anxiety- and depression-associated emotional eating, self-efficacy for controlled eating, and the transfer of exercise-related self-regulation to eating-related self-regulation. Given the scope of the obesity problem, extensions of this research within field settings are warranted to accelerate application opportunities.

Sauna Bathing as an Alternative Adjunct Therapy in the Prevention and Treatment of Chronic Health Conditions Including Cardiovascular Disease, Neurodegenerative Disease, Metabolic Disease, and Mental Health Disorders

Sauna bathing is a time-efficient, cost-effective health modality that has the potential to mimic the heat thermogenesis and cardiovascular effects of exercise. In recent years, researchers have been able to measure the benefits of sauna on human performance, endurance, and cardiovascular health. While many studies have investigated sauna use and its effect on athletic performance, fewer studies have investigated the use of sauna as a medical treatment for chronic health conditions. This review compiles the proven effects of sauna on human physiology and investigates its applications in the treatment of patients with chronic disease. Sauna use appears to be safe in most patient populations and is shown to be both tolerable and effective in patient populations with cardiovascular disease and late stages of congestive heart failure. Multiple cardiovascular benefits were demonstrated in the review including improved perfusion in peripheral arterial disease, decreased ventricular arrhythmias, 51% reduced annual cardiovascular mortality and 47% reduced annual risk of developing hypertension in men using the sauna 4-7 times per week. Finnish cohort studies have additionally exhibited reductions in lifetime annual risk of dementia by 66% in men using the sauna 4-7 times per week. It is suggested that increased heat shock protein expression through heat exposure may be responsible for the neuroprotective benefits of lifetime sauna use. Sauna has also displayed benefits in metabolic disease by reducing hemoglobin A1C and aiding heat acclimation in diabetics through improved thermoregulation. In mental health research, sauna use has shown potential in the treatment of depression by improving objective depression scores. Another study exhibited that sauna use was able to increase appetite in patients with severe depression and coexisting appetite suppression. Additionally, in cohort studies sauna is shown to be correlated to reduced annual risk of developing psychosis across the lifespan. By compiling and reviewing the current research on sauna bathing, education and guidance are provided to medical providers regarding the potential use of sauna as a treatment adjunct for patients with various conditions including cardiovascular disease, neurodegenerative disease, metabolic disease, and mental health disorders.

The Effects of Cardiovascular Exercises on Body Mass Index and Vital Capacity among Students of Sargodha University

This research was designed to evaluate the effect of cardiovascular exercises on body mass index (BMI) and vital capacity (VC) among student aged between 21-27 years (M � SD 22.3� 3.05). The experimental research study was applied to 54 University students of Sargodha. Data were analyzed by using SPSS version 24.0. P-value ? 0.05 was considered significant. The result showed that the average BMI of the control group and experimental groups was 20.73�3.02 vs 21.51�3.21. The effectiveness of cardiovascular exercise on Vital capacity on Pre and post-test of the experimental group was -56.91272 � 22.03192 with a pvalue of 0.000, which was showed there was a highly significant improvement in vital capacity of students and compare with the control group. It was concluded that body masses index and vital capacity is significantly improved in university students of the experimental group as a result of 10 weeks of the cardiovascular exercise training program. Conclude that there is a significant difference between the effects of cardiovascular exercise and daily routine sports activities on BMI.

Cardiovascular Effects of Exercise in Young Hypertensives

Sedentary habits are largely responsible for the alarming rise in the prevalence of hypertension among young individuals. Regular aerobic exercise has been shown to reduce not only blood pressure (BP) in resting conditions but also BP reactivity to stressors. Much less is known about the long-term effects of physical activity on target organ damage in hypertension. Some studies have documented that exercise is able to decrease rather than increase left ventricular mass and that even competitive athletics have beneficial effects on the heart. In addition, physical activity during leisure has been found to be inversely associated with the progression of subclinical atherosclerosis and to delay aging dependent arterial stiffness. Isolated systolic hypertension in physically active young people is often an innocent clinical condition caused by an elevated pulse pressure amplification and low wave arterial reflection from peripheral sites, due to increased arterial elasticity. The above findings support a strategy of exercise training as an initial approach in the management of young sedentary patients in the early stages of hypertension. Caution should be used in subjects with more severe hypertension and every hypertensive athlete should be thoroughly investigated to exclude target organ damage and coronary artery disease.

Integration of the metabolic and cardiovascular effects of exercise

Most of the essays in this volume have adopted a reductionist approach and have focused on the biochemistry either in skeletal muscle or in the vascular wall. There is however a complex interaction between the biochemistry in the endothelium of the microvascular wall, the vascular smooth muscle and the skeletal muscle fibres involving signalling pathways in the three tissues and an intense exchange of signal molecules between them. In the present essay an integrative overview is given of this complex metabolic interaction and the impairments in it that lead to type 2 diabetes and cardiovascular disease.A reduced nitric oxide production by the (micro)vascular endothelium is identified as the key event and is reversible by regular exercise and a reduced calorie intake. The chapter also contains a description of the complex metabolic network controlled by the inducible transcription factor nuclear factor-kappaB, that is activated in more advanced stages of the chronic diseases, and either leads to repair of the microvascular wall or to irreversible damage and the severe complications of end stage cardiovascular disease and type 2 diabetes.

Differential effects of exercise on aortic mitochondria

Routine exercise is widely recognized as cardioprotective. Exercise induces a variety of effects within the cardiovasculature, including decreased mitochondrial damage and improved aerobic capacity. It has been generally thought that the transient increase in oxidative stress associated with exercise initiates cardioprotective processes. Somewhat paradoxically, increased oxidative stress associated with cardiovascular disease (CVD) risk factors is thought to play an important role in the promotion and development of CVD. Hence, it is possible that CVD risk factors that increase oxidative stress (e.g., hypercholesterolemia) may modulate the cardioprotective effects of exercise. In this regard, the interaction between CVD risk factors and exercise on atherosclerotic lesion development and basal oxidant load is less defined. To determine the influence of preexistent hypercholesterolemia on cardioprotective effects of exercise, atherosclerotic lesion formation, oxidant load, mitochondrial damage, protein nitration (3-nitrotyrosine levels), and mitochondrial enzyme activities were determined in aortic tissues from normocholesterolemic (C57 control) and hypercholesterolemic [apoliprotein E-deficient (apoE(-/-))] mice after 16 wk of regular exercise. In normocholesterolemic mice, regular exercise was associated with decreased mitochondrial damage and oxidant load and increased SOD2 and adenine nucleotide translocator activities. Exercise did not decrease endogenous oxidant load and mitochondrial damage in hypercholesterolemic mice and did not reduce atherosclerotic lesion development. These data are consistent with the notion that CVD risk factors associated with increased oxidative stress can alter the benefits of exercise and that mitochondrial damage appears to be correlated with the cardiovascular effects of exercise.

Cardiovascular responses in humans to experimental chewing of gums of different consistencies

Although the cardiovascular effects of exercise have been extensively investigated in man, little attention has been paid to such responses to jaw muscle activity. The aim here was to investigate the general cardiovascular effects of chewing activity in a single-blind, cross-over design. Ten healthy individuals performed one of the following chewing tasks in four separate sessions: chewing a very hard gum, chewing a moderately hard gum, chewing a soft gum, and “empty chewing” without a bolus. Unilateral chewing of gum or empty chewing was performed for 20 min on the participant’s most convenient chewing side at a constant rate of 80 cycles/min. In each session, heart rate and arterial blood pressure were recorded together with electromyographic activity in the masseter and anterior temporalis muscles on the chewing side. Ratings of perceived masticatory fatigue were recorded with visual analogue scales. The heart rate and blood pressure were significantly increased (ANOVA; p⩽0.01) during the chewing tasks and the increases were, in parallel with the muscle activity, more pronounced the harder the gum. With the very hard gum, heart rate increased by up to 11 beats/min, the systolic blood pressure was 14 mmHg (1.9kPa) higher, and the diastolic blood pressure was 11 mmHg (1.5kPa) higher. The perceived fatigue was proportional to the level of muscle activity. After 10 min of recovery from exercise, heart rate and arterial blood pressures were slightly but still significantly elevated. The results demonstrate that chewing is associated with general circulatory effects proportional to the bolus resistance.

Ventilation and acid-base recovery following exhausting activity in an air-breathing fish

The effects of exhausting activity in normoxic (PO2=20.7 kPa) and hypoxic (PO2<2.7 kPa) water on ventilatory, metabolic and acid-base variables were examined in spotted gar (Lepisosteus oculatus) to determine the role of the air-breathing organ in supporting active metabolism and recovery. The level of aquatic hypoxia used effectively eliminated the gills as a site of O2 uptake, forcing the fish to respire as a unimodal air-breather. Swimming duration (until exhaustion) was not significantly different in normoxic and hypoxic water. Blood gas, acid-base, cardiovascular and ventilatory variables were monitored at intervals from 15 min to 24 h post-exercise. Fish survived exhaustive exercise using a combination of anaerobic metabolism and increased ventilation (aerial and aquatic), despite respiratory and metabolic acidoses. The cardiovascular effects of exercise (heart rate and dorsal aortic blood pressure) were minor. The metabolic effects of exercise were similar to those in unimodal water-breathing fish; however, even hypoxic animals recovered from exhaustive exercise by 24 h. Thus, the results of this study show that air breathing in L. oculatus allows gar to exercise to the same extent in normoxic and hypoxic water and enables them to re-establish blood gas and acid-base balance after exhaustive activity even in hypoxic water. <P>

Cardiovascular Effects of Exercise: Role of Endothelial Shear Stress

Experimental, epidemiologic and clinical studies have provided strong evidence that physical exercise has beneficial effects on multiple physiological variables affecting cardiovascular health (lipoprotein levels, rest blood pressure and heart rate, carbohydrate tolerance, neurohormonal activity). Regular exercise has been shown to slow the progression of cardiovascular disease and to reduce cardiovascular morbidity and mortality. More recently, exercise-induced increases in blood flow and shear stress have been observed to enhance vascular function and structure. By increasing the release of nitric oxide and prostacyclin, shear stress augments endothelium-dependent vasodilation and inhibits multiple processes involved in atherogenesis and restenosis. In this review we discuss the underlying mechanisms by which exercise-induced blood flow and shear stress exert their salutary effects on cardiovascular remodeling.

Cardiovascular effects of exercise in hamsters with experimental thiamine deficiency.

The hemodynamic effects of daily treadmill exercise were evaluated in hamsters with experimental thiamine deficiency to test the hypothesis that increased energy consumption might be a contributory factor in the pathogenesis of beriberi heart disease. Daily exercise enhanced thiamine deficiency and was manifested by earlier development of symptoms of neuropathy compared to non-exercised animals. Hemodynamics of exercised thiamine deficient animals were characterized by significantly lower O2 consumption, lower cardiac output, and lower left ventricular minute work, compared to exercised, pair-fed control animals. Left ventricular end-diastolic pressure was slightly but not significantly higher in thiamine deficient animals. Left ventricular function, therefore, was depressed in this group. There was no evidence of hyperkinetic circulation, cardiomegaly or congestive heart failure. Neuropathy and depressed ventricular function, characteristic of pure thiamine deficiency, were observed in the absence of high cardiac output or high output failure, the pathogenesis of which may require other unknown factors.