1. Attention is focused on the ubiquitous prevalence of bronchospasm of non-allergic origin. 2. The main causative factors of this condition are enumerated, with commentary on the role of various lung diseases, heart failure, cough, extraneous environmental factors, psychogenic influences and reflex irritation of the peribronchial smooth muscles from extrapulmonary sources. 3. Adverse sequels of non-allergic bronchospasm are discussed, with particular reference to wheezing, dyspnea, cough, chest pain, tussive insufficiency and pseudohypertrophic emphysema. 4. The cardinal aim of treatment is to restore the normotonic (eutonic) status of the peribronchial and peribronchiolar smooth muscles. Adequate treatment of the underlying provocative condition is emphasized and the author's favorable clinical experience is recorded, with bronchospasmolytic and anticholinergic drugs and with corticosteroids.
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