Background: The comparative outcomes of Liquid and Solid cancer in Sudden cardiac arrest (SCA) population is not well studied in literature. Methods: The National inpatient sample database from the year 2015-2018 was used to compare liquid cancer and Solid cancer patients that underwent sudden cardiac arrest (SCA). Means and medians were calculated for continuous variables, p -value (<0.05), and Pearson chi-square used to calculate weighted outcomes. Results: A total of 7,695.00 SCA patients (solid cancer n= 475.0 ; liquid cancer n=7,220.0) were included in our study analysis. Among participants, male and female percentages in Solid (65.3 % and 34.7%) and liquid cancers (61.9% and 38.1%) respectively. The median age of solid cancer with SCA was 67 years (IQR 51-77) while median age for liquid cancer with SCA was 70 years (IQR 58-79). The median length of stay of solid cancer with SCA is 8 days (IQR 3-20) whereas liquid cancer with SCA is 5 days (IQR 1-13). There was no statistical significant difference among solid or liquid cancer with SCA in terms of in-hospital mortality (76.6% vs 78.1%, p = 0.742), acute kidney injury (55.8% vs 61%, p = 0.319), major bleeding (5.3% vs 10.7%, p = 0.098), transfusion requirement (82.1% vs 81.2%, p = 0.837), and cardiogenic shock (3.2% vs 3.6%, p= 0.824) in sudden cardiac arrest (SCA) patients respectively. There was higher prevalence of cerebrovascular accidents (3% vs 7.4%, p= 0.024) and mechanical circulatory support use including ventricular assist devices (VAD) and Extracorporeal membrane oxygen (ECMO) in liquid cancer patients as compared to solid cancers in SCA (1.1% vs 3.3%, p = 0.001). Conclusion: Liquid cancers with SCA can have higher prevalence of stroke and mechanical circulatory support requirement as compared to solid cancers with SCA