Fossil-fuels combustion is currently the main driving force of industrialization; however, it has resulted in CO2 emission that challenges sustained socioeconomic growth. One way to reduce CO2 emissions is to sequester it into saline aquifers or depleted hydrocarbon reservoirs. In this study, CO2 absorption in different aqueous salt solutions is elucidated. CO2 absorption in different salines is also simulated using PHREEQC software to predict the concentration of different species formed by saline-CO2 interactions at equilibrium. Investigated parameters include concentration of different salts at low salinity condition, type of cations and anions, temperature, and carbonate rock on the CO2 absorption and storage in aqueous media at high pressures. Results revealed that both initial absorption rate and final absorbed amount of CO2 in aqueous salt solution decay in the order of MgSO4 > Na2SO4 > CaCl2 > MgCl2 > NaCl. For a given anion in the dissolved salt, the presence of divalent cations promotes CO2 absorption more than that of monovalent cations. Also, for equivalence cations the one with a higher charge density promotes CO2 absorption. It is also evident that for a given cation in the dissolved salt the associated anion which has a higher charge density hinders CO2 absorption more than that with a lower charge density. Similar pattern is maintained for CO2 absorption in saturated carbonate rock. PHREEQC simulations revealed that concentrations of precipitated carbonate salts in CO2-saturated Na2SO4 and NaCl brines are higher than those of the other brines. Moreover, increasing temperature increases concentration of precipitated carbonate salts in CO2-saturated MgSO4, CaCl2, and MgCl2 brines while it has an opposite effect on precipitated carbonate salts formed due to CO2 absorption in Na2SO4 and NaCl brines.