Carbon Dioxide Content Of Blood Research Articles

Pulmonary arterial shunting in man during forward acceleration.

The arterial blood gases were determined during forward acceleration 90∘ to the acceleration vector at 6 g and 8 g breathing room air and at 8 g breathing 100% oxygen. Arterial saturation fell to 84% at 6 gand 75% at 8 g. Prebreathing O2 for 15 min prior to acceleration with continued inhalation during the acceleration plateau only partially corrected the undersaturation to 86% at 8 g. Recovery was not complete in 3 min unless O g therapy was used. Whole blood carbon dioxide content was depressed at 6 g and 8 g on room air, but this was corrected by O g inhalation. However, during the recovery period while breathing oxygen the carbon dioxide content was depressed. pH was reduced and pCO g elevated slightly during each acceleration period. Since cardiac output and alveolar ventilation have been reported to be essentially unaltered during forward acceleration at these magnitudes, the observed effects must represent substantial alterations in the individual ventilation to blood flow ratios throughout the lung, with approximately 50% of the cardiac output shunted through totally nonventilated areas at 8 g. There also must be some inadequately perfused or nonperfused peripheral areas, as evidenced by the fall in CO g content and pH and the accumulation of a substantial O g debt previously reported during acceleration. Note: With the Technical Assistance of Alice M. Caton and Justin L. Taylor, Jr. Submitted on June 12, 1961

The Determination of the Carbon Dioxide Content of Blood and Plasma by Means of Conway Units

The Determination of the Carbon Dioxide Content of Blood and Plasma by Means of Conway Units

The diagnostic importance of the blood carbon dioxide content of patients with central cyanosis

1. 1. The arterial blood carbon dioxide contents were measured in fifty-five patients with central cyanosis. Sixteen had congenital heart disease and two of these had also congestive heart failure; twenty-three had chronic bronchitis and emphysema; and sixteen had congestive heart failure complicating chronic bronchitis and emphysema. 2. 2. The arterial blood carbon dioxide content was below normal in the majority of patients with cyanotic congenital heart disease, normal or raised in the majority of patients cyanosed from chronic bronchitis and emphysema, and invariably raised in patients with congestive heart failure complicating chronic bronchitis and emphysema. 3. 3. The blood carbon dioxide content appears to be of diagnostic importance in patients with central cyanosis.

Effects of vigorous physical exercise on cerebral circulation and metabolism

1. 1. The effects of vigorous muscular exercise in the upright posture were studied in thirteen normal subjects and compared with the changes resulting from motionless standing. 2. 2. Exercise resulted in a decrease in cerebral vascular resistance and an increase in cerebral oxygen consumption. The decrease in mean cerebral blood flow which results from motionless standing did not occur with exercise. There was no change in cerebral respiratory quotient. 3. 3. Although exercise resulted in a striking fall in blood carbon dioxide content and pH, no correlations could be made between these changes and the alterations in cerebral circulatory or metabolic functions. There was a close correlation between changes in cerebral vascular resistance and cerebral oxygen consumption, though the reason for this is not known.

Physiologic studies of the groundhog (Marmota monax).

An investigation of hibernation was carried out with groundhogs in order to study their unusual tolerance to very low body temperatures. The normal carbon dioxide content of the blood of groundhogs, even while they are in the nonhibernating phase, is higher than that of dogs and humans. In groundhogs, the transition from the nonhibernating to the hibernating phase involves a fall in body temperature to as low as 3° C. and appears to be associated with (1) an increase in the oxygen content and the carbon dioxide content of whole blood, (2) an elevation of the serum magnesium and serum potassium, (3) an increase in hematocrit values, and (4) a decrease in the blood sugar level. Direct microscopic examination of the peripheral circulation in vivo showed a free-flowing stream with no intravascular agglutination of red blood cells or vascular stasis in groundhogs, dogs, and rabbits at a body temperature of 20° C. or in groundhogs during hibernation at temperatures as low as 5° C.

Oxygen carrying capacity of the blood of dormant ground squirrels.

ArticleOxygen Carrying Capacity of the Blood of Dormant Ground SquirrelsArthur Svihla, and Howard C. BowmanArthur SvihlaFrom the University of Washington, Seattle, Washington, and Howard C. BowmanFrom the University of Washington, Seattle, WashingtonPublished Online:31 Oct 1952https://doi.org/10.1152/ajplegacy.1952.171.2.479MoreSectionsPDF (391 KB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformation Cited BySquirrels24 January 2020Hibernation and Gas Exchange1 January 2011Quantitative and functional analysis of peripheral blood mononuclear cells in European brown bear (Ursus arctos arctos)Comparative Biochemistry and Physiology Part A: Physiology, Vol. 112, No. 3-4Seasonal patterns in the physiology of the European brown bear (Ursus arctos arctos) in FinlandComparative Biochemistry and Physiology Part A: Physiology, Vol. 109, No. 3Respiration and Acid-Base State in HibernationCirculatory responses of Rana catesbeiana to temperature, season and previous thermal historyComparative Biochemistry and Physiology Part A: Physiology, Vol. 51, No. 1Studies on the red blood cell oxygen affinity and 2,3-diphosphoglyceric acid in the hibernating woodchuck (Marmota monax)Comparative Biochemistry and Physiology Part A: Physiology, Vol. 48, No. 3Several blood and circulatory changes in the hibernation of the 13-lined ground squirrel, Citellus tridecemlineatusComparative Biochemistry and Physiology Part A: Physiology, Vol. 44, No. 2Effects of simulated high altitude on hibernating and non-hibernating rodentsComparative Biochemistry and Physiology, Vol. 34, No. 4Environmental temperature and the body fluid system of the fresh-water teleost—III. Hematology and blood volume of thermally acclimated brook trout, Salvelinus fontinalisComparative Biochemistry and Physiology, Vol. 28, No. 2Oxygen and carbon dioxide content of blood in toad (bufo melanostictus) during hibernation and non-hibernationComparative Biochemistry and Physiology, Vol. 18, No. 3HibernationThe Care and Use of Hibernating MammalsHistochemical localization of some enzymes in the kidney of a hibernatorJournal of Cellular and Comparative Physiology, Vol. 56, No. 2The effect of hibernation on the replacement of blood in the golden hamsterJournal of Experimental Zoology, Vol. 136, No. 3Blood Hepari Level and the Status of Blood Coagulation in Cats During Hypothermia26 September 2008 | Archives Internationales de Physiologie et de Biochimie, Vol. 64, No. 1 More from this issue > Volume 171Issue 2October 1952Pages 479-481 Copyright & PermissionsCopyright © 1952 by American Physiological Societyhttps://doi.org/10.1152/ajplegacy.1952.171.2.479PubMed13007819History Received 28 May 1952 Published online 31 October 1952 Published in print 31 October 1952 Metrics

How Acts the Administration of Oxygen and Carbon Dioxide against Carbon Monoxide Poisoning ?

A review of the studies on the blood alkalinity occourring by the carbon monoxide poisoning and like conditions is given as an introductory, because the findings, in fact the former findings, of the pioneer of the carbon dioxide therapy in respect to the blood alkalinity have very close relation to the recommendation of that therapy. The present writer himself, who conducted inhalation of carbon monoxide on rabbits, is able to find also definitely the beneficial effect of mixing carbon dioxide to oxygen for treatment of carbon monoxide poisoning, clearly superior to the pure oxygen. Carbon monoxide is more rapidly eliminated, the oxygen content of blood is more rapidly restored and the carbon dioxide content of blood more rapidly still. The pH of blood, which shows usually the acidosis, inclines to shift further. And all the tendencies increase according to the increase of the content of carbon dioxide in the inhalational mixture. With these results we do not mean, contrary to critics, that the alkali administration should act detrimentally against the carbon monoxide poisoning and like conditions. Kamei's work demonstrates it beyond doubt. One must take care, there is little need to say, of its dosage. Further it may be said in passing that we will not take the present outcome as unconditionally proving a view of some critic that intensification of acidosis is never harmful to the organism though it is wholly settled that the use of carbon dioxide-oxygen mixture largely accelerates the expulsion of CO from blood, the restoration of the O2, and CO2, content of blood.

The oxygen and carbon dioxide content of blood from the internal jugular and other veins: Lennox, William G., and Leonhardt, Erna: Arch. Int. Med. 46: 630, 1930

The oxygen and carbon dioxide content of blood from the internal jugular and other veins: Lennox, William G., and Leonhardt, Erna: Arch. Int. Med. 46: 630, 1930

Some Metabolic Changes Occurring in Prolonged Diathermy Treatments.

Studies on the respiratory exchange and the sugar, non-protein nitrogen, chlorides and carbon dioxide content of blood, were made on anesthetized (morphine + amytal) dogs. Tracheotomy was done and connection made to a Benedict universal apparatus. Blood analyses were done by standard methods. The high frequency current had the following characteristics: wave length—200 meters, relatively high voltage, currents from 500 to 1000 milliamperes. Electrodes were placed on the left upper arm and right thigh, or on either side of the head. Treatment continued from 1 to 3 hours. Temperature measurements were made with thermocouples and mercury thermometers. The respiratory metabolism invariably increased—in some cases 150%. Body temperatures were elevated 5 to 7°C. When blood sugar was initially relatively high there was a gradual depletion during diathermy; in cases of low initial concentrations a preliminary rise was noted followed by a fall. The end result was a marked hypoglycemia (30 to 50 mg. per 100 cc. blood). Non-protein nitrogen was in some cases increased to 200% of normal. Chlorides failed to exhibit any gross changes. The carbon dioxide content of whole blood and of plasma invariably dropped to a rather low level (about 35 vol. %). Panting was induced in some animals, during which time the respiratory rate exceeded 250 per minute.

Hydrogen ion Concentration and Carbon Dioxide Content of Blood of Parathyroidectomized Dogs.

In recent years research in experimental and clinical tetany has led to the view that tetany occurs when the reaction of the blood shifts to the alkaline side. The fact that acid producing salts su...

The carbon dioxide content of blood and alveolar air in obstructed expiration

The carbon dioxide content of blood and alveolar air in obstructed expiration