1176 Endurox claims to increase fat metabolism, raise anaerobic threshold, and improve recovery measured by heart rate and lactate. Good scientific research by Cheuvront et al (1999) and Plowman et al (1999) does not support the claims made by Endurox on endurance performance. Both of these studies analyzed a submax endurance task, but did not look at a recovery exercise bout. PURPOSE: To analyze exercise time to fatigue, recovery, and a recovery exercise bout with an Endurox supplement in comparison to a carbohydrate-electrolyte drink (PowerAde) and a Placebo. METHODS: Three trials (Endurox, PowerAde, Placebo) on a cycle ergometer were conducted in double blind random order. 18 recreationally active subjects (9 males, 9 females) between 20–40 years of age participated. The drinks were administered pre, during, and immediately after initial exercise to fatigue. The initial exercise was 45 minutes at 65% intensity, followed by two minute increments until fatigue. This was followed by 15 minutes of rest, and then another incremental ride to fatigue (recovery bout). VO2, HR, RER, lactate, glucose, RPE, sweat loss, Ve, and time to fatigue were measured. RESULTS: The Endurox (50.8 min) trial had significantly less time to fatigue than the PowerAde (51.9 min) trial and the Placebo trial (52.0 min) for the initial exercise bout, and slightly less (non-significant) time to fatigue during the recovery bout. No significant differences in lactate, RPE, VO2, Ve, RER, and glucose were found. Interestingly, sweat loss was significantly less during the Endurox trial (1353 ml), compared to the Placebo (1472 ml) and PowerAde (1540 ml) trials. Heart rate tended to be higher during the latter portion of the initial exercise bout for the Endurox trial compared to the other two trials, and was significantly higher (146.7 bpm) than the Placebo trial (138.5 bpm), but not the PowerAde trial (142.5 bpm) at minute 35 of the initial exercise bout. Lactate and HR during the recovery bout were not significantly different. CONCLUSIONS: Endurox has no performance benefit and may even have a performance decrement during incremental exercise to fatigue compared to a Placebo and PowerAde. The reduced time to fatigue may be related to reduced thermoregulation, since HR was higher and Sweat loss was reduced.