Aiming at the selection of modern auto parts design schemes, an evaluation method of automobile parts design scheme for intelligent manufacturing is proposed. Considered the environment-friendly factors and traditional manufacturing factors, the evaluation index system of automobile parts design scheme was established, which taken technology, environment, economy and quality reliability as the first level evaluation index, and 12 second level indexes under the first level index. The game theory method was used to comprehensively consider the proportion of subjective and objective weights to determine the composite weight of each index. Aimed at the certainty and uncertainty of the evaluation index, the set pair analysis relative closeness method was used to calculate the composite weight and established the model. Three sets of automobile panel design schemes of a company were selected, and the mathematical model was used to calculate them. With the help of C language program, the advantages and disadvantages of the three design schemes were evaluated, and the optimal scheme was obtained. The calculation example proves that the method is true and effective, conforms to the background of modern intelligent manufacturing, and the calculation is simple, and has good feasibility and practicability.