Cancer Mortality In Brazil Research Articles

Evolution of thyroid cancer mortality in adults in Brazil

To assess the trend of thyroid cancer mortality in Brazil between 1980 and 2010. An ecological study of time series. Mortality rates for thyroid cancer adjusted by age according to gender were calculated between 1980 and 2010. Data were analyzed by three distinct strategies: polynomial regression, joinpoint analysis, and moving averages. Over 70% of deaths occur in the elderly, regardless of sex. Among young adults, the mortality rate is low, with no difference between men and women. Among mature adults and elderly, mortality is increasing, and significantly, for women. There is a trend of decreasing mortality in all female adults and overall population, and in males and 40-59 years and overall population, both excluding the elderly, with statistical significance. Knowledge about trends allows setting priorities and allocating resources toward positive changes in this scenario in the Brazilian population.

Cancer incidence, hospital morbidity, and mortality in young adults in Brazil

There are still relatively few studies in the world on cancer incidence and mortality in young adults. The current study aimed to explore cancer distribution in young adults in Brazil. A descriptive study was conducted on cancer incidence (selected State capitals), hospital morbidity, and mortality (Brazil and selected capitals) in the 20-24-year age strata in 2000-2002, and trends in cancer mortality rates in Brazil in 1980-2008 in the same population. Testicular cancer was the principal anatomical site in young adult males; in young adult women, the main sites were thyroid, uterine cervix, and Hodgkin disease. Brain cancer was the principal cause of death from cancer in both sexes, and time trends in mortality showed an increase in mortality from brain cancer in men and from lymphocytic leukemia in both sexes. As a whole, the results show an epidemiological pattern of cancer in young adults with regional distribution characteristics.

Cervical cancer mortality trends in Brazil: 1980-2009

The objective was to describe time trends in cervical cancer mortality rates in Brazil as a whole and in the country's major geographic regions and States from 1980 to 2009. This was an ecological time series study using data recorded in the Mortality Information System (SIM) and census data collected by the Brazilian Institute of Geography and Statistics (IBGE). Analysis of mortality trends was performed using Poisson regression. Cervical cancer mortality rates in Brazil tended to stabilize. In the geographic regions, a downward trend was observed in the South (-4.1%), Southeast (-3.3%), and Central-West (-1%) and an upward trend in the Northeast (3.5%) and North (2.7%). The largest decreases were observed in the States of São Paulo (5.1%), Rio Grande do Sul, Espírito Santo, and Paraná (-4.0%). The largest increases in mortality trends occurred in Paraíba (12.4%), Maranhão (9.8%), and Tocantins (8.9%). Cervical cancer mortality rates stabilized in the country as a whole, but there was a downward trend in three geographic regions and 10 States, while two geographic regions and another 10 States showed increasing rates.

INCREASE INCOME AND MORTALITY OF COLORRECTAL CANCER IN BRAZIL, 2001-2009

Several international studies have observed a correlation between the improvement of socio-demographic indicators and rates of incidence and mortality from cancer of the colon and rectum. The objective of this study is to estimate the correlation between average per capita income and the rate of colorectal cancer mortality in Brazil between 2001 and 2009. We obtained data on income inequality (Gini index), population with low incomes (½ infer the minimum wage/month), average family income, per capita ICP and mortality from colon cancer and straight between 2001-2009 by DATASUS. A trend analysis was performed using linear regression, and correlation between variables by Pearson's correlation coefficient. There was a declining trend in poverty and income inequality, and growth in ICP per capita and median family income and standardized mortality rate for colorectal cancer in Brazil. There was also strong positive correlation between mortality from this site of cancer and inequality (men r = -0.30, P = 0.06, women r = -0.33, P = 0.05) income low income (men r = -0.80, P<0.001, women r = -0.76, P<0.001), median family income (men r = 0.79, P = 0.06, women r = 0.76, P<0.001) and ICP per capita (men r = 0.73, P<0.001, women r = 0.68, P<0.001) throughout the study period. The increase of income and reducing inequality may partially explain the increased occurrence of colorectal cancer and this is possibly due to differential access to food recognized as a risk factor, such as red meat and high in fat. It is important therefore to assess the priority of public health programs addressing nutrition in countries of intermediate economy, as is the case of Brazil.

Cancer incidence, hospital morbidity, and mortality in young adults in Brazil

There are still relatively few studies in the world on cancer incidence and mortality in young adults. The current study aimed to explore cancer distribution in young adults in Brazil. A descriptive study was conducted on cancer incidence (selected State capitals), hospital morbidity, and mortality (Brazil and selected capitals) in the 20-24-year age strata in 2000-2002, and trends in cancer mortality rates in Brazil in 1980-2008 in the same population. Testicular cancer was the principal anatomical site in young adult males; in young adult women, the main sites were thyroid, uterine cervix, and Hodgkin disease. Brain cancer was the principal cause of death from cancer in both sexes, and time trends in mortality showed an increase in mortality from brain cancer in men and from lymphocytic leukemia in both sexes. As a whole, the results show an epidemiological pattern of cancer in young adults with regional distribution characteristics.

Disparities in female breast cancer mortality rates in Brazil between 1980 and 2009

OBJECTIVE:To describe the temporal trends in female breast cancer mortality rates in Brazil in its macro-regions and states between 1980 and 2009.METHODS:This was an ecological time-series study using data on breast cancer deaths registered in the Mortality Data System (SIM/WHO) and census data on the resident population collected by the Brazilian Institute of Geography and Statistics (IBGE/WHO). Joinpoint regression analyses were used to identify the significant changes in trends and to estimate the annual percentage change (APC) in mortality rates.RESULTS:Female breast cancer mortality rates in Brazil tended to stabilize from 1994 onward (APC = 0.4%). Considering the Brazilian macro-regions, the annual mortality rates decreased in the Southeast, stabilized in the South and increased in the Northeast, North, and Midwest. Only the states of Sao Paulo (APC = -1.9%), Rio Grande do Sul (APC = -0.8%) and Rio de Janeiro (APC = -0.6%) presented a significant decline in mortality rates. The greatest increases were found in Maranhao (APC = 12%), Paraiba (APC = 11.9%), and Piaui (APC = 10.9%).CONCLUSION:Although there has been a trend toward stabilization in female breast cancer mortality rates in Brazil, when the mortality rate of each macro-region and state is analyzed individually, considerable inequalities are found, with rate decline or stabilization in states with higher socioeconomic levels and a substantial increase in those with lower socioeconomic levels.

Trends in lung cancer mortality in Brazil from the 1980s into the early 21st century: age-period-cohort analysis

The aim of this study was to describe the pattern of trends in lung cancer mortality in Brazil and identify the effects of the factors age, period and cohort (APC) on mortality rates. A time series study was conducted using secondary population-based data. Lung cancer mortality rates by sex were calculated for the period 1980 to 2007. APC models were adjusted to identify the influence of age, period and cohort effects on rates. Lung cancer mortality rates are significantly higher among men. Specific rates for men over the age of 64 and for women of all ages are increasing. There was a greater increase of adjusted rates among women. With respect to the age effect, mortality risk increases with age starting with the earliest age groups. With regard to the cohort effect, there is a lesser risk of mortality among men born after 1950 and an increasing risk across all cohorts among women. The results regarding younger generations indicate that present trends are likely to continue. The cohort effect among women suggests an increasing trend in mortality rates, whereas a decrease in rates among men under the age of 65 suggests that this trend will continue. These trends reflect tobacco control measures adopted since 1986.

INCREASE INCOME AND MORTALITY OF COLORRECTAL CANCER IN BRAZIL.

Background and Aims: The objective of this study is to determine the correlation between average per capita income and the rate of colorrectal cancer mortality in Brazil between 2000 and 2007. Materials and methods: We obtained data on median household income and mortality rate for colon, rectum and anus between 2001 2007 by DATASUS. A trend analysis was performed using linear regression, and correlation between variables by Pearson’s correlation coefficient. Results: There was a tendency towards an increase average family income and standardizedmortality rate of colon, rectum and anus in Brazil. There was also strong positive correlation (r = 0.81, p &lt;0.001) between incomeand mortality for this cancer located throughout the study period. Conclusion: Theincrease in income may partially explain the increased occurrence of cancer of thecolon, rectum and anus, and this is possibly due to differential access to food recognized as a risk factor, such as red meat and fat food.É therefore important Assess the priority of public health programs addressing nutrition in countries with intermediate economy, as is the case in Brazil.

P1-401 Temporal trend in and spatial distribution of lung cancer mortality in Brazil between 1979 and 2004: magnitude, regional patterns, and gender-related differences

IntroductionLung cancer is a major public health problem in Brazil. The aim of this study was to describe the temporal trend and the spatial distribution of mortality from tracheal, bronchial,...

P2-288 Trend of lung cancer mortality in Brazil, 1980 to 2007

ObjectivesTo describe the trends in mortality from lung cancer in Brazil and to identify the effects of age, period and birth cohort on these rates by sex.MethodsWe conducted a time...

SP1-104 Cancer mortality trends in Brazilian capitals and inland counties between 1980 and 2006

ObjectiveTo analyse the trends in mortality for the overall and major types of cancer, by sex, in Brazil and major regions for State Capitals and inland counties between 1980 and...

P2-109 Increase income and mortality of colorectal cancer in Brazil

ObjectiveThe objective of this study is to determine the correlation between average per capita income and the rate of colorectal cancer mortality in Brazil between 2000 and 2007.Materials and MethodsWe...

Trends in cancer mortality in Brazil, 1980–2004

Scanty information, limited to selected areas of the country, is available on cancer mortality in Brazil. Age-standardized (world population) mortality rates between 1980 and 2004, derived from the WHO database, were computed for all cancers and 24 major cancer sites in Brazil. Joinpoint regression analyses were used to identify the significant changes in trends and estimate annual percent change (APC) in rates. Total cancer mortality rates increased over the last decade in men (APC = 0.5) to reach 101.2/100 000, and in women (APC = 0.3) to reach 71.3/100 000. In men, upward trends were observed for cancers of the oral cavity and pharynx with a rate of 5.9/100 000 in 2000-2004, intestines (whose rate, however was low, i.e. 7.6), prostate (12.2), and leukemias (3.4). Male lung cancer increased until 1993 (APC = 1.39) and decreased thereafter (APC = -0.29), with a relatively low rate of 16.2/100 000 in 2000-2004. In women, there were steady upward trends for cancers of the lung (APC = 2.3), reaching 6.2/100 000 in 2000-2004, and leukemias (2.5). Breast cancer mortality leveled off at around 10/100 000 in the last decade, whereas declines were observed for cancers of the uterus, whose rate (8.3) however, remained comparatively high. Declines were observed for stomach cancer in both sexes, with rates of 11.1 in men and 4.6 in women. In conclusion, the key issues of cancer mortality in Brazil are the high rates of head and neck cancers in men and (cervix) uterine cancer in women, that is, in principle cancers that are largely avoidable through prevention, screening, and early diagnosis.

Tendências da mortalidade por câncer nas capitais dos estados do Brasil, 1980-2004

Cancer mortality rates began to decline in developed countries in the 1990s, but their behavior in developing countries is less well-known. An earlier study on cancer mortality in Brazil showed a declining mortality trend for cancer as a whole. however the quality of data results raised some criticism t. The population of state capitals comprises about a quarter of the total Brazilian population and for these cities mortality data available have a better quality than for the entire country, enabling analyses of trends in cancer rates based on more accurate data.Mortality and population data were collected from government databases (SIM/DATASUS and IBGE, respectively). Age-adjusted (world standard) and age-specific mortality rates were calculated for both genders . Linear regression was used to investigate changes in trends.For all cancers as a whole mortality rates declined throughout the study period for both men and women (-4.6% and -10.5%, respectively). For both genders , the cancer that decreased most was stomach cancer. Among men, lung cancer death rates presented a slight reduction, while prostate cancer rates increased. Among women, "uterus, site unspecified' presented a downward trend, while lung cancer rates increased. The trend for breast cancer remained stable, and cervix uterus rates showed a slight increase at the end of the period.As already seen in developed countries, all cancer mortality rates tended to decline in Brazilian state capitals over the period 1980-2004, a tendency largely due to a decline in stomach cancer death rates for both genders.

Pesticide Sales and Adult Male Cancer Mortality in Brazil: An Ecological Study

Pesticide Sales and Adult Male Cancer Mortality in Brazil: An Ecological Study

Pesticide sales and adult male cancer mortality in Brazil

In Brazil, where the use of pesticide grows rapidly, studies that evaluate the impact of pesticide exposure on cancer incidence and mortality are very scarce. In this study, we evaluated the degree of correlation between pesticide sales in 1985 in eleven Brazilian states and cancer mortality rates during 1996-1998. Information of all cancer deaths occurred in men 30-69 years old from 1996 to 1998 were collected from National Mortality System. Single and multiple linear regression coefficients were obtained to assess the relationship between per capita sales of pesticides in 1985, specific-site cancer mortality rates (prostate, soft tissue, larynx, leukemia, lip, esophagus, lung, pancreas, bladder, liver, testis, stomach, brain, non-Hodgkin's lymphoma, and multiple myeloma) during 1996-1998, and several covariates. In addition, states were stratified into three groups according to tertiles of pesticides sales and cancer mortality rate ratios (MRR) were then calculated using first tertile as reference. Finally, a factor analysis was performed to reveal unapparent relationships between pesticide use and cancer mortality. Pesticide sales showed statistically significant correlation with the mortality rates for the cancers of prostate (r=0.69; p=0.019), soft tissue (r=0.71; p=0.015), leukemia (r=0.68; p=0.021), lip (r=0.73; p=0.010), esophagus (r=0.61; p=0.046), and pancreas (r=0.63; p=0.040). Moderate to weak correlations were observed for the cancers of larynx, lung, testis, bladder, liver, stomach, brain, and NHL and multiple myeloma. In addition, correlation between pesticide sales and specific-site cancer mortality rates was reinforced by multiple regression analysis. For all specific-sites, cancer mortality rates were significantly higher in the states of moderate (2nd tertile) and high (3rd tertile) pesticide sales, with MRR ranging from 1.11 to 5.61. Exploring hidden relationships between pesticide sales and cancer mortality in Brazil, through a factor analysis, revealed that affluence; public policies and lifestyle behaviors may explain almost 70% of the variance of the studied association. The results suggest that population exposure to pesticides in the 1980s in some Brazilian States may have been associated with selected cancer sites observed a decade later.

Impacto e (i)mobilização: um estudo sobre campanhas de prevenção ao câncer

During the past few years, the Brazilian government and society have been engaged in planning actions designed to prevent and control several types of cancer that can be either prevented or treated successfully if diagnosed early. However, recent data on cancer mortality rates in Brazil rebut the effectiveness of these actions. The literature shows that psychosocial factors associated with these campaigns have not received sufficient attention from the authorities and campaign producers. This paper analyzes comments by fifteen women undergraduates on seven cancer prevention campaign slogans, assessing their mobilization power on the basis of their association with the representation of cancer as death. The findings suggest an important difference between the impacts of these campaigns and their effective power to mobilize the population to seek treatment and prevention. This leads to the conclusion that psychosocial elements such as the social representation of cancer, self-esteem, relationships between individuality and collectivity, gender discourse and the ideological nature of the slogans must be taken into account when preparing cancer prevention campaigns.

Tendência temporal e distribuição espacial da mortalidade por câncer de pulmão no Brasil entre 1979 e 2004: magnitude, padrões regionais e diferenças entre sexos

To describe the temporal trend in and spatial distribution of mortality from tracheal, bronchial, and lung cancer in Brazil from 1979 to 2004. Mortality data by gender and geographic region were obtained from the Mortality Database created by the Ministry of Health in 1975. Demographic data were collected from the national censuses, from population counts, and from population estimates made in non-census years. Mortality rates were standardized according to the direct method, and the trends were analyzed by gender and geographic region using the Prais-Winsten method for generalized linear regression. Lung cancer mortality accounted for approximately 12% of the overall neoplasia-related mortality during the period. There was a trend toward an increase for both genders and in all regions, except for the male population in the southeast region, whose rates remained steady between 1979 and 2004. The highest rates were observed in the south and southeast regions. However, the northeast region was the one that presented the greatest increase, followed by the central-west and north regions. In all regions, the increase in mortality rates was higher in women. The increase in lung cancer mortality in Brazil between 1979 and 2004 requires public measures that can minimize exposition to risk factors, mainly tobacco, and allow greater access to health care facilities for diagnosis and treatment.

Correlation Between Pesticide Sales and Specific-Site Cancer Mortality Rates in Brazil

Correlation Between Pesticide Sales and Specific-Site Cancer Mortality Rates in Brazil

Trends in childhood renal cancer mortality in Brazil, 1980–2000

Mortality from childhood cancers has shown substantial declines in developed countries since 1960, with smaller favourable trends in South America. This study describes mortality trends in renal childhood cancer mortality in São Paulo state, Brazil, from 1980 to 2000. The age-standardised mortality rates among the boys decreased from 0.36 per 100,000 inhabitants in 1984 to 0.09 in 1992, whereas the observed corresponding decline among girls was from 0.43 per 100,000 inhabitants in 1981 to 0.07 in 1990. Statistically significant declining trends in mortality rates were observed for boys (adjusted r(2) = 0.51, P < 0.001) and also for girls (adjusted r(2) = 0.40, P = 0.002), achieving in this group a significant reduction in age-standardised mortality rates in the period (annual percentage change = -4.21). Consistent decrease in mortality rates from childhood renal cancer was noted at São Paulo state. In the absence of changes in incidence rates, this decline could be attributed to the improvement in treatment protocols and supportive measures.