A collection of 81 plugs were obtained from the Humilly-2 borehole (France), that reached the Permo-Carboniferous sediments at a depth of 3051 m. Experimental measurements of physical parameters and mineralogical analysis were performed to explore the links between sedimentary facies and seismic characteristics and provide a key tool in the interpretation of seismic field data in terms of geological formations. The plugs, cylinders of 22.5 mm in diameter and sim30 mm in length were collected parallel and perpendicular to the bedding in order to explore their anisotropy. Ultrasound wave propagation was measured at increasing confining pressure conditions up to 260 MPa, a pressure where all micro-fractures are considered closed. The derivatives of velocities with pressure were established, allowing the simulation of lithological transitions at in-situ conditions. At room conditions, measured grain densities (kg/m3) range from 2630 to 2948 and velocities vary from 4339 to 6771 and 2460 to 3975 {text {m/s}} for P- and S-waves propagation modes, respectively. The largest seismic-reflections coefficients were calculated for the interface between the evaporitic facies of the Keuper (Lettenkohle) and the underlying Muschelkalk carbonates (R_{text {c}}= 0.3). The effective porosity has the range of 0.23% to 16.65%, while the maximum fluid permeability left( text {m}^{text {2}}right) is 9.1 times text {10}^{-{text {16}}}. A positive correlation between porosity and ultrasound velocity has been observed for P- and S-waves. The link between velocities and modal content of quartz, dolomite, calcite, and micas has been explored. This paper presents a unique set of seismic parameters potentially useful for the calibration of seismic data in the Geneva Molasse Basin.
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