There have a survey of the connection between natural resistance and stress resistance among Holstein heifer showing domestic-usable features.
 Arecord-keepingofdisease incidence was conducted.
 There was a study of calves-live-weight and of their spontaneous resistance.
 Serum bactericidal and lysozyme activity were determined.
 For impartial assessment of phagocytosis, activity and intensity of phagocytosis were taken into account.
 There was an analysis of lactation milk production of calved cows, after giving birth of calves under review.
 There was a study of production traits of test animals after termination of first lactation.
 There have been established high criteria of age succession of live-weight-features in all age periods (r = +0.8 – +0.9), which affirms the consistency in calf management.
 Average month live-weight-increase in the test group was 25.3 ± 118 kg.
 There was revealed a positive correlation between an average month live-weight-increase and serum bactericidal activity(r = +0.28 ± 0.13).
 Otherwise an invert correlation between lysozyme activity and average month live-weight-increase was determined.
 At the age of 7 months the invert correlation in these criteria amounts r = -0.585 ± 0.22**, Р < 0.01.
 The efficiency-influence of calved cows on the live-weight of 6-month-calves was probable and amounted ηх2 = 29.6% (Р > 0.001).
 The efficiency-influence of calved cows on the stress resistance of calves turned out statistically significant and amounted ηх2 = 39.5%.
 A statistically significant influence of the age of the first service (ηх2 = 12.3%) and that of incidence of illness (ηх2 = 7%) in early age on the milk production was not identified.
 The animals, showing normal-stress-status, had probably, higher level of milk production in 305 day of the first lactation, (+1843 кг, Р < 0.05), than stress-sensitive animals.
 Apart from this, the stress-resistant calves showed, probably, higher live-weight.
 In summary, the inconstancy between live-weight and the criteria of natural resistance should be considered during cattle-breeding aiming disease-resistance.