At present, the intelligent translation of computer is developing rapidly. In this paper, the overall design of interactive intelligent auxiliary translation platform based on multi-strategy is studied. In this paper, the algorithm of similarity of sentences is deeply studied. According to the needs of English–Chinese translation memory system, the similarity between sentences is calculated from the sentence syntax and semantic based on syntactic and semantic English sentence similarity calculation method. Finally, the author uses the English–Chinese translation of Navigator 7.0 manual to examine the effect of the algorithm platform developed in this paper. The experimental results show that the proposed algorithm improves the speed of translation by about 35%.