This study evaluated the nutritive potential of detoxified neem kernel cake as source of protein for broiler chickens. Diet-control was 100 percent soybean based. Diets, 1, 2, 3 and 4 had detoxified neem kernel cake included at 25, 50, 75 and 100 percents respectively. These four diets were evaluated in comparison to control, in a seven- week growth and metabolism trial using two hundred day old broiler chicks with an average initial live weight of 39.3 + 0.1g, divided in to five groups of forty chicks per treatment in a Complete Randomized Design. Five broiler chicks were caged individually per treatment. Feed and water were offered ad libitum. Daily feed intake, daily body weight changes and mortality rate were determined. At the end of seven- week feeding trial, three birds were randomly selected from each treatment and were slaughtered for carcass evaluation. The results revealed that the broiler chickens fed 25% detoxified neem kernel cake diet had improved growth performance comparable to chickens fed soybean diet. Thus detoxified neem kernel cake can be incorporated up to 25% in broiler chicken feeding without any adverse effect on performance of the chickens.