As China enters a new stage of building Chinese-style modernization in an all-round way, rural grass-roots cadres, as an important force in rural grass-roots governance, bear the important responsibility of promoting rural economic development, social stability, and improvement of people's livelihood. This paper takes the construction mechanism of rural grass-roots cadres under the leadership of Party building as the core and discusses its significance to rural governance and rural development. Combining with case analysis, this paper proves that the combination mechanism of cadre selection and appointment, cadre training and education, cadre assessment, Party organization guidance and supervision, and cadre incentive and guarantee provides strong support and assurance for the construction of rural grass-roots cadres. It is of great significance to promote the effective implementation of the strategy of rural revitalization.