Heavy metals can cause serious environmental and human health problems, and their removal from wastewater is critical to protect our planet and communities. This study investigated the ability of crushed pomegranate peel to remove mercury and cadmium ions from contaminated water as a function of different experimental parameters. The experimental results showed that the pH of the solution influenced the adsorptive removal of heavy metals, with the best performance observed at pH 4.8. Optimization studies and process balance modeling were performed to optimize the process for commercial use. The performance of pomegranate peel was compared with that of other materials, and the highest adsorption capacities for both cadmium (Ca (II)) and mercury (Hg (II)) ions were observed to be 89.59 and 42.125 mg/g, respectively. The results were interpreted using the Langmuir model, which provided the best fit to describe the behavior of the process.