We constrain the parameters of a representative new physics model with a possible dark matter (DM) signature from a global Cabibbo-Kobayashi-Maskawa (CKM) fit analysis. The model has neutral quark current interactions mediated by a scalar, impacting the semileptonic and purely leptonic meson decays at one loop. We take this opportunity to update the fit results for the Wolfenstein parameters and the CKM elements with and without a contribution from the new model using several other updated inputs. In addition, we analyze and include the $B\ensuremath{\rightarrow}{D}^{*}\ensuremath{\ell}{\ensuremath{\nu}}_{\ensuremath{\ell}}$ decay in the CKM fit. The newly available inputs on the relevant form factors from lattice calculations are included, and the possibility of new physics effects in $B\ensuremath{\rightarrow}{D}^{*}\ensuremath{\ell}{\ensuremath{\nu}}_{\ensuremath{\ell}}$ is considered. We obtain tight constraints on the relevant new physics parameters. We study the possible implications of this constraint on DM phenomenology. Apart from DM, the bounds are also applicable in other relevant phenomenological studies.
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